Results 71 to 80 of about 436,329 (309)

Optimal Control of Polymer Flooding Based on Maximum Principle

open access: yesJournal of Applied Mathematics, 2012
Polymer flooding is one of the most important technologies for enhanced oil recovery (EOR). In this paper, an optimal control model of distributed parameter systems (DPSs) for polymer injection strategies is established, which involves the performance ...
Yang Lei   +4 more
doaj   +1 more source

A Clustering Method Based on the Maximum Entropy Principle

open access: yesEntropy, 2015
Clustering is an unsupervised process to determine which unlabeled objects in a set share interesting properties. The objects are grouped into k subsets (clusters) whose elements optimize a proximity measure.
Edwin Aldana-Bobadilla   +1 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Maximum principle and the fourth order boundary value problem

open access: yesMathematical Modelling and Analysis, 2011
This paper is devoted to the study the nonlinear boundary value problem . We state a maximum principle related with the operator  and apply it to prove the existence and approximation of solutions to the problem (i), (ii), in presence of properly ordered
Inara Yermachenko
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

The positive maximum principle on symmetric spaces [PDF]

open access: yes, 2020
We investigate the Courrège theorem in the context of linear operators that satisfy the positive maximum principle on a space of continuous functions over a symmetric space. Applications are given to Feller–Markov processes.
Le Ngan, T., Applebaum, D.
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

A class of highly degenerate elliptic operators: maximum principle and unusual phenomena

open access: yes, 2017
We discuss the validity of the maximum principle below the principal eigenvalue for viscosity solutions of the Dirichlet problem in bounded domains $$ {\cal P}^-_{k}(D^2u)+H(x,\nabla u)+\mu u=0\quad\mbox{in}\;\Omega,\quad u=0\quad\mbox{on}\;\partial ...
Galise, Giulio
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Principal eigenvalues for k-Hessian operators by maximum principle methods

open access: yes, 2017
For fully nonlinear k-Hessian operators on bounded strictly (k-1)-convex domains of Euclidian space, a characterization of the principal eigenvalue associated to a k-convex and negative principal eigenfunction will be given as the supremum over values of
Payne, Kevin
core  

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