Results 91 to 100 of about 8,396,712 (346)

Implementation Plan for Five Total Maximum Daily Loads for Bacteria in Four Austin Streams [PDF]

open access: yes, 2015
The implementation plan provides an overview of five creeks and precisely details how the Total Maximum Daily Load Team will respond to pollutants in the water.EXECUTIVE SUMMARY: The Texas Commission on Environmental Quality (TCEQ) is required to ...
Improving Austin Streams Coordination Committee
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

A maximum principle for second order parabolic system

open access: yesJournal of Numerical Analysis and Approximation Theory, 1976
Not available.
Anton Mureşan
doaj   +2 more sources

A Reappraisal of the Principle of Maximum Power

open access: yesEcologies
Living organisms continuously capture and transform free energy to survive and grow. The Maximum Power Principle (MPP) states that life evolves to maximize power—the rate of energy acquisition and conversion into useful forms—within prevailing ...
Alberto Gianinetti
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Stochastic maximum principle for SPDEs with delay [PDF]

open access: yes, 2016
In this paper we develop necessary conditions for optimality, in the form of the Pontryagin maximum principle, for the optimal control problem of a class of infinite dimensional evolution equations with delay in the state. In the cost functional we allow
G. Guatteri, F. Masiero, Carlo Orrieri
semanticscholar   +1 more source

Mean-Field Pontryagin Maximum Principle [PDF]

open access: yesJournal of Optimization Theory and Applications, 2015
We derive a maximum principle for optimal control problems with constraints given by the coupling of a system of ordinary differential equations and a partial differential equation of Vlasov type with smooth interaction kernel.
Mattia Bongini   +3 more
semanticscholar   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Optimal Control of Polymer Flooding Based on Maximum Principle

open access: yesJournal of Applied Mathematics, 2012
Polymer flooding is one of the most important technologies for enhanced oil recovery (EOR). In this paper, an optimal control model of distributed parameter systems (DPSs) for polymer injection strategies is established, which involves the performance ...
Yang Lei   +4 more
doaj   +1 more source

A Clustering Method Based on the Maximum Entropy Principle

open access: yesEntropy, 2015
Clustering is an unsupervised process to determine which unlabeled objects in a set share interesting properties. The objects are grouped into k subsets (clusters) whose elements optimize a proximity measure.
Edwin Aldana-Bobadilla   +1 more
doaj   +1 more source

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