Results 41 to 50 of about 3,605,812 (301)

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The Latent Maximum Entropy Principle [PDF]

open access: yes, 2012
We present an extension to Jaynes’ maximum entropy principle that incorporates latent variables. The principle of latent maximum entropy we propose is different from both Jaynes’ maximum entropy principle and maximum likelihood estimation, but can yield ...
Wang, Shaojun   +2 more
core   +1 more source

Combining experiments and simulations using the maximum entropy principle. [PDF]

open access: yesPLoS Computational Biology, 2014
A key component of computational biology is to compare the results of computer modelling with experimental measurements. Despite substantial progress in the models and algorithms used in many areas of computational biology, such comparisons sometimes ...
Wouter Boomsma   +2 more
doaj   +1 more source

Pontryagin Maximum Principle for Incommensurate Fractional-Orders Optimal Control Problems

open access: yesMathematics, 2023
We introduce a new optimal control problem where the controlled dynamical system depends on multi-order (incommensurate) fractional differential equations.
Faïçal Ndaïrou, Delfim F. M. Torres
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

A maximum principle [PDF]

open access: yesJournal of the Australian Mathematical Society, 1979
AbstractLet K be a nonempty compact set in a Hausdorff locally convex space, and F a nonempty family of upper semicontinuous convex-like functions from K into [–∞, ∞). K is partially ordered by F in a natural manner. It is shown among other things that each isotone, upper semicontinuous and convex-like function g: K → [ – ∞, ∞) attains its K-maximum at
openaire   +2 more sources

A class of highly degenerate elliptic operators: maximum principle and unusual phenomena

open access: yes, 2017
We discuss the validity of the maximum principle below the principal eigenvalue for viscosity solutions of the Dirichlet problem in bounded domains $$ {\cal P}^-_{k}(D^2u)+H(x,\nabla u)+\mu u=0\quad\mbox{in}\;\Omega,\quad u=0\quad\mbox{on}\;\partial ...
Galise, Giulio
core   +1 more source

An Algebraic Flux Correction Scheme Satisfying the Discrete Maximum Principle and Linearity Preservation on General Meshes

open access: yes, 2017
This work is devoted to the proposal of a new flux limiter that makes the algebraic flux correction finite element scheme linearity and positivity preserving on general simplicial meshes. Minimal assumptions on the limiter are given in order to guarantee
Knobloch, Petr   +2 more
core   +1 more source

Bauer's Maximum Principle for Quasiconvex Functions [PDF]

open access: yes, 2023
This note shows that in Bauer's maximum principle, the assumed convexity of the objective function can be relaxed to ...
Ball, Ian
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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