Results 91 to 100 of about 7,463,510 (319)
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Remarks on the strong maximum principle for nonlocal operators
Electronic Journal of Differential Equations, 2008 In this note, we study the existence of a strong maximum principle for the nonlocal operator $$ mathcal{M}[u](x) :=int_{G}J(g)u(x*g^{-1})dmu(g) - u(x), $$ where $G$ is a topological group acting continuously on a Hausdorff space $X$ and $u in C(X)
Jerome Coville
doaj
A maximum principle for infinite horizon delay equations [PDF]
, 2012 We prove a maximum principle of optimal control of stochastic delay equations on infinite horizon. We establish first and second sufficient stochastic maximum principles as well as necessary conditions for that problem.
Agram, N. +3 more
core +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Maximum principles, sliding techniques and applications to nonlocal equations
Electronic Journal of Differential Equations, 2007 This paper is devoted to the study of maximum principles holding for some nonlocal diffusion operators defined in (half-) bounded domains and its applications to obtain qualitative behaviors of solutions of some nonlinear problems.
Jerome Coville
doaj
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
Maximum Principles for Dynamic Equations on Time Scales and Their Applications
Journal of Applied Mathematics, 2014 We consider the second dynamic operators of elliptic type on time scales. We establish basic generalized maximum principles and apply them to obtain weak comparison principle for second dynamic elliptic operators and to obtain the uniqueness of Dirichlet
Shuqing Zhou, Hui Li
doaj +1 more source
Maximum principles for Laplacian and fractional Laplacian with critical integrability
, 2019 In this paper, we study maximum principles for Laplacian and fractional Laplacian with critical integrability. We first consider $-\Delta u(x)+c(x)u(x)\geq 0$ in $B_1$ where $c(x)\in L^{p}(B_1)$, $B_1\subset \mathbf{R}^n$. As is known that $p=\frac{n}{2}$
Lü, Yingshu
core
FEBS Open Bio, EarlyView.This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc +8 more
wiley +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source