Results 81 to 90 of about 2,214,339 (284)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Two symmetry problems in potential theory

Electronic Journal of Differential Equations, 2001
We consider two overdetermined boundary value problems as variants on J. Serrin's 1971 classical results and prove in both cases that the domains must be Euclidean balls.
Tewodros Amdeberhan
doaj  

Necessary conditions for continuous parameter stochastic optimization problems [PDF]

variational theory application to continuous parameter stochastic optimization problems to derive maximum principles in linear ...
Kushner, H. J.
core   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Maximum principles for hypersurfaces with vanishing curvature functions in an arbitrary Riemannian manifold

Anais da Academia Brasileira de Ciências, 2002
In this paper we generalize and extend to any Riemannian manifold maximum principles for Euclidean hypersurfaces with vanishing curvature functions obtained by Hounie-Leite.Neste trabalho nós generalizamos e estendemos para uma variedade Riemanniana ...
FRANCISCO X. FONTENELE, SÉRGIO L. SILVA
doaj   +1 more source

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu, Yuxi Gong, Weilin Xu, Xingjian Sun, Gefei Jiang, Lei Qiu, Kexin Shi, Mengxing Wu, Yinjiao Fei, Jinling Yuan, Jinyan Luo, Yurong Li, Yuandong Cao, Minhong Pan, Shu Zhou   +14 more
wiley   +1 more source

Comprehensive Studies on Operational Principles for Maximum Power Point Tracking in Photovoltaic Systems

IEEE Access, 2019
Maximum power point tracking (MPPT) is essential in Photovoltaic (PV) systems, which has drawn significant research effort in the past. The operation is to adjust the power interfaces so that the operating characteristics of the consumption and the PV ...
Xingshuo Li, Qi Wang, Huiqing Wen, Weidong Xiao   +3 more
doaj   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Two maximum principles for a nonlinear fourth order equation from thin plate theory

Electronic Journal of Qualitative Theory of Differential Equations, 2014
We develop two maximum principles for a nonlinear equation of fourth order that arises in thin plate theory. As a consequence, we obtain uniqueness results for the corresponding fourth order boundary value problem under Navier boundary conditions as ...
Cristian-Paul Danet
doaj   +1 more source