Results 131 to 140 of about 1,263,980 (273)
Targeted review of the maximum residue levels (MRLs) for dimethomorph
Abstract In accordance with Article 43 of Regulation (EC) No 396/2005, the European Commission requested EFSA to perform a targeted risk assessment for dimethomorph considering the residue definition and the toxicological reference values (TRVs) derived during the renewal of the approval of dimethomorph and the most recent version of the EFSA ...
openaire +3 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
According to Article 12 of Regulation (EC) No 396/2005, EFSA has reviewed the maximum residue levels (MRLs) currently established at European level for the pesticide active substance glyphosate.
Reasoned Opinion
semanticscholar +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Setting of a temporary maximum residue level for chlorantraniliprole in hops
In accordance with the Article 53 of the Regulation (EC) 1107/2009, the United Kingdom granted a 120‐day emergency authorisation for the use of chlorantraniliprole in hops following an application by the British Hop Association.
European Food Safety Authority (EFSA)
doaj +1 more source
Statistical properties of contact vectors
We study the statistical properties of contact vectors, a construct to characterize a protein's structure. The contact vector of an N-residue protein is a list of N integers n_i, representing the number of residues in contact with residue i.
A. F. Pereira de Araujo +37 more
core +1 more source
According to Article 12 of Regulation (EC) No 396/2005, EFSA has reviewed the maximum residue levels (MRLs) currently established at European level for the pesticide active substance copper compounds. To assess the occurrence of copper compounds residues
Reasoned Opinion
semanticscholar +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Modification of the existing maximum residue level for pendimethalin in lettuce
In accordance with Article 6 of Regulation (EC) No 396/2005, the evaluating Member State, the United Kingdom, received an application from UK Horticultural Development Company to modify the existing maximum residue level (MRL) for the active substance ...
European Food Safety Authority (EFSA)
doaj +1 more source
Eigenvector Centrality Distribution for Characterization of Protein Allosteric Pathways
Determining the principal energy pathways for allosteric communication in biomolecules, that occur as a result of thermal motion, remains challenging due to the intrinsic complexity of the systems involved.
Batista, Victor S. +8 more
core

