Results 241 to 250 of about 1,263,980 (273)

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman, Asako Takanohashi, Joshua Y. Joung, Geraldine W. Liu, Kaley Arnold, Amy Pizzino, Walter Faig, Sarah Woidill, Sona Narula, Adeline L. Vanderver   +9 more
wiley   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer, Simon Faissner, Ralf Gold, Aiden Haghikia   +3 more
wiley   +1 more source

Association of CDKN2A/B Homozygous Deletion and Extent of Resection With Survival of Patients With WHO CNS5 Grade 4 Astrocytoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives WHO grade 4 astrocytomas are associated with poor prognosis, and their prognostic factors remain controversial. This study aimed to identify the prognostic factors and develop a management algorithm for these patients. Methods This study retrospectively included 151 CNS5 adult grade 4 astrocytomas from two medical centers.
Jiawei Cai, Guanglin Zhu, Qiu He, Chen Luo, Lingyun Zhuo, Xingfu Wang, Yiming Chen, Xiaoyong Chen, Wendong You, Jiaheng Xu, Yuanxiang Lin, Dezhi Kang, Shuai Wu, Zanyi Wu   +13 more
wiley   +1 more source

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Maximum Residue Levels: Fact or Fiction?

Human and Ecological Risk Assessment: An International Journal, 2003
Maximum residue levels (MRLs) are trading standards that represent the maximum residue that could be found if a crop protection product (CPP) is applied according to critical good agricultural practice (cGAP). Foodstuffs are monitored for MRL compliance and exceedence can have economic, social and political consequences.
Hyder, Kieran, Travis, Kim Z., Welsh, Zoe K., Pate, Ian   +3 more
openaire   +4 more sources

Residue extrapolation and group maximum residue level recommendation for four pesticides in the four kinds of vegetable crop groups

International Journal of Environmental Analytical Chemistry, 2021
The residue behaviours of difenoconazole, bifenthrin, thiamethoxam and its metabolite clothianidin on representative crops such as cucumber, bitter gourd, loofah, zucchini, tomato, cherry tomato, eggplant, cowpea, kidney bean, celery, and fennel were ...
Yanli Bian, Gang Guo, Fengmao Liu, Xiaohan Li   +3 more
semanticscholar   +1 more source

Declining harmonization in maximum residue levels for pesticides

British Food Journal, 2018
Purpose Maximum residual limits (MRLs) for pesticides are based on science. This is true both for MRLs devised by national governments and multilaterally through the Codex. Science-based Codex MRLs are internationally harmonized to facilitate trade. Since the 1990s, an increasing number of countries have devised national MRLs and eschewed those of the
May Yeung, William A. Kerr, Blair Coomber, Matthew Lantz, Alyse McConnell   +4 more
openaire   +1 more source

Establishment of Maximum Residue Levels for minor uses

EPPO Bulletin, 2007
The availability of plant protection products that are authorized for minor uses in the European Community is becoming restricted due to the stringent EU review process. An associated problem is the lack of sufficient residues data for minor uses necessary for the establishment of MRLs (Maximum Residue Levels). The policy for MRL setting is focussed on
openaire   +1 more source

Chemical-specific maximum allowable levels for pesticide residues in dietary supplements

Food and Chemical Toxicology, 2019
Dietary supplements are regulated by the U.S. FDA as a subset of foods. Most botanical dietary ingredients do not have pesticide tolerances, resulting in the enforcement of zero tolerance or general maximum residue limits (GMRL), rather than utilizing science-informed tolerances.
Rebecca E, Adams, Julie A, Brickel, Virunya S, Bhat   +2 more
openaire   +2 more sources

Pesticides Maximum Residues Levels (MRLs) in Halal Food

2023
Moawya Ibrahim Yousif Abdalla, Abdel Moneim Elhadi Sulieman, Marwa Mohamed Eisa Eltohami, Isam M. Abu Zeid   +3 more
openaire   +1 more source