Results 41 to 50 of about 308,567 (190)

Vector Copy Distribution at a Single-Cell Level Enhances Analytical Characterization of Gene-Modified Cell Therapies

open access: yesMolecular Therapy: Methods & Clinical Development, 2020
The ability to deliver transgenes into the human genome using viral vectors is a major enabler of the gene-modified cell therapy field. However, the control of viral transduction is difficult and can lead to product heterogeneity, impacting efficacy and ...
Ilaria Santeramo   +6 more
doaj   +1 more source

Phase boundary anisotropy and its effects on the maze-to-lamellar transition in a directionally solidified Al-Al2Cu eutectic

open access: yes, 2019
Solid-solid phase boundary anisotropy is a key factor controlling the selection and evolution of non-faceted eutectic patterns during directional solidification. This is most remarkably observed during the so-called maze-to-lamellar transition.
Akamatsu, Silvère   +3 more
core   +1 more source

Une traduction oulipienne des oulipiens ?

open access: yesCatalonia, 2018
When considering the translation of Oulipian literature, it is not sufficient to raise the question of translation procedures or methods. Instead, the question must be approached from a tactical perspective, addressing the tactical manoeuvres necessary ...
Ramon Lladó
doaj   +1 more source

Mazes to Study the Effects of Spatial Complexity, Predation and Population Density on Mate Finding

open access: yesInsects, 2020
The difficulty to locate mates and overcome predation can hamper species establishment and population maintenance. The effects of sparseness between individuals or the effect of predators on the probability of population growth can be difficult to ...
Lloyd D. Stringer   +7 more
doaj   +1 more source

Considerations in the Design of Non-Clinical Development Programmes to Support Non-Viral Genetically Modified Mesenchymal Stromal Cell Therapies

open access: yesPharmaceutics, 2021
Due to their immune suppressive pharmacology, regenerative capacity, and immune privileged status, mesenchymal stromal cells (MSCs) are an attractive cell type to treat a variety of diseases.
Valeria Iansante   +2 more
doaj   +1 more source

A Review of the Historical Evolutionary Process of Dry and Water Maze Tests in Rodents

open access: yesBasic and Clinical Neuroscience, 2020
This research provides an overview of the historical advances of the maze tests that are widely used to assess the cognitive impairments in rodents. Particularly, this study focuses on the issue of learning and memory behavioral tests, including dry and ...
Fahimeh Mohseni   +2 more
doaj  

Omega-3 Fatty Acids Prevent Post-Traumatic Stress Disorder-Induced Memory Impairment

open access: yesBiomolecules, 2019
Post-traumatic stress disorder (PTSD) is a psychiatric disorder that can happen after exposure to a traumatic event. Post-traumatic stress disorder is common among mental health disorders that include mood and anxiety disorders. Omega-3 fatty acids (OMGs)
Laiali Alquraan   +4 more
doaj   +1 more source

Effects of environmental enrichment on behavioral responses to novelty, learning, and memory, and the circadian rhythm in cortisol in growing pigs [PDF]

open access: yes, 2000
Previously we showed that pigs reared in an enriched environment had higher baseline salivary cortisol concentrations during the light period than pigs reared under barren conditions.
Blokhuis, Harry J.,   +6 more
core   +1 more source

Pierwiastki męskie i kobiece w filmie "Aleksandra" w reżyserii Aleksandra Sokurowa

open access: yesAdeptus, 2019
The masculine and feminine elements in Aleksandr Sokurov’s film Alexandra The aim of this article is to present the fundamentals of the Great Mother archetype in Aleksandr Sokurov’s film Alexandra using the anthropological-morphological method of ...
Agnieszka Magdalena Korycka
doaj   +1 more source

Inter/Intra‐Atrial Dissociation in Patients With Maze Procedure and Its Clinical Implications: Pseudo‐Block and Pseudo‐Ventricular Tachycardia

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Severe conduction delay and inter/intra‐atrial dissociation may occur in patients who undergo an extensive catheter ablation or a maze procedure for atrial tachyarrhythmia.
Ungjeong Do   +6 more
doaj   +1 more source

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