Results 41 to 50 of about 56,014 (312)

Advanced Design for Weakly Coupled Resonators by Automatic Active Optimization

open access: yesAdvanced Materials Technologies, EarlyView.
An Automatic Active Optimization (AAO) strategy integrates machine learning predictors and genetic algorithms in a closed‐loop workflow. By iteratively expanding its dataset with new discoveries, AAO overcomes the limits of conventional methods. This approach finds superior microstructural designs beyond the initial sample space. We demonstrate this on
Wei Yue   +8 more
wiley   +1 more source

Liquid Metal Sensors for Soft Robots

open access: yesAdvanced Robotics Research, EarlyView.
This review thoroughly reviews liquid metal sensors in soft robots. Their unique material properties like high conductivity and good biocompatibility are analyzed. Working principles are classified, and applications in environmental perception, motion detection, and human—robot interaction are introduced.
Qi Zhang   +7 more
wiley   +1 more source

Barnes Maze Procedure for Spatial Learning and Memory in Mice

open access: yesBio-Protocol, 2018
The Barnes maze is a dry-land based rodent behavioral paradigm for assessing spatial learning and memory that was originally developed by its namesake, Carol Barnes.
Matthew Pitts
doaj   +1 more source

The effect of silver nanoparticles on learning and memory in rodents: "a systematic review"

open access: yesJournal of Occupational Medicine and Toxicology, 2023
Background Silver nanoparticles (AgNPs) are widely used in medicine owing to their antiseptic activity and inducing cell death. Despite AgNPs' importance in nano-engineering and medical benefits, animal studies have shown silver toxicity can damage ...
Farshad Safaei   +6 more
doaj   +1 more source

Dissociating Behavior and Spatial Working Memory Demands Using an H Maze

open access: yesBio-Protocol, 2021
The development of mazes for animal experiments has allowed for the investigation of cognitive maps and place cells, spatial working memory, naturalistic navigation, perseverance, exploration, and choice and motivated behavior.
Hannah Wirtshafter   +2 more
doaj   +1 more source

Disengaging the Engine: Histone Deacetylases 1 and 2‐Mediated Acetylation of Hexokinase‐2 Regulates Energy Metabolism in Microglia Following Intracerebral Hemorrhage

open access: yesAdvanced Science, EarlyView.
This study demonstrates that HDAC1/2 knockout in microglia alleviates neurological deficits, preserves white matter, and accelerates hematoma clearance after ICH. HDAC1/2 inhibition reduces HK2 acetylation, shifts metabolism from glycolysis to fatty acid oxidation, reduces inflammation, and enhances phagocytosis.
Zhiwen Jiang   +9 more
wiley   +1 more source

Delta Opioid Receptors within the Cortico‐Thalamic Circuitry Underlie Hyperactivity Induced by High‐Dose Morphine

open access: yesAdvanced Science, EarlyView.
Morphine activates the excitatory cingulate cortex–intermediate rostrocaudal division of zona incerta (Cg‐ZIm) pathway to drive hyperlocomotion in mice. Inhibiting the Cg‐ZIm pathway attenuates both acute and chronic morphine‐induced hyperlocomotion, while its activation mimics morphine's motor effects.
Chun‐Yue Li   +13 more
wiley   +1 more source

Midbrain PAG Astrocytes Modulate Mouse Defensive and Panic‐Like Behaviors

open access: yesAdvanced Science, EarlyView.
Astrocytes in the midbrain periaqueductal gray (PAG) dynamically encode threat intensity and shape defensive action selection in mice. Real‐time Ca2+ imaging reveals robust astrocytic activation during predator odor and CO2 exposure. Aberrant astrocytic Ca2+ overactivation disrupts goal‐directed escape, biases behavior toward freezing, and induces ...
Ellane Barcelon   +10 more
wiley   +1 more source

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