Results 51 to 60 of about 56,014 (312)
F1000Research, 2014 Learning and memory as well as long-term potentiation (LTP) depend on Ca2+ influx through the NMDA-type glutamate receptor (NMDAR) and the resulting activation of the Ca2+ and calmodulin-dependent protein kinase (CaMKII).
Ivar S. Stein +2 more
doaj +1 more source
Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages
Advanced Science, EarlyView.Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu +14 more
wiley +1 more source
Perinatal Exposure to Low-Dose Bisphenol A Impairs Spatial Learning and Memory in Male Rats
Journal of Pharmacological Sciences, 2013 Bisphenol A (BPA) is an estrogenic endocrine disruptor used for producing polycarbonate plastics and epoxy resins. This study investigated the effects of perinatal BPA exposure on learning and memory, general activity, and emotionality in male Sprague ...
Rika Kuwahara +4 more
doaj +1 more source
Evaluation of the neuroprotective potential of Trans-cinnamaldehyde in female Wistar rat model of insulin resistance [PDF]
Journal of Krishna Institute of Medical Sciences University, 2023 Background: Chronic hyperglycemia in type 2 diabetes is associated with altered cognitive function. Trans-cinnamaldehyde (TCA) is one of the active components in cinnamon.
Samson E Olorunnado +2 more
doaj
On a Unique Solution of a T-Maze Model Arising in the Psychology and Theory of Learning
Journal of Function Spaces, 2022 In the form of a T, a T-maze is an experimental design in which each trial consists of decisions between two or more options. It contains choices with particular kinds of symmetries that have gained considerable attention in psychology and learning ...
Ali Turab, Wajahat Ali, Juan J. Nieto
doaj +1 more source
Animal Behaviour, 2017 Rats, mice and other rodents are well-known for their ability to solve complex spatial tasks, such as learning to negotiate complicated mazes. This ability might be an adaptation for the fossorial habit that characterizes most rodents, but the scarcity of data from other taxa prevents us from confirming this hypothesis.
LUCON XICCATO, TYRONE, BISAZZA, ANGELO
openaire +3 more sources
Advanced Science, EarlyView.This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang +9 more
wiley +1 more source
Effects of Boswellia Papyrifera Gum Extract on Learning and Memory in [PDF]
Iranian Journal of Basic Medical Sciences, 2010 Objective(s)Learning is defined as the acquisition of information and skills, while subsequent retention of that information is called memory. The objective of the present study was to investigate the effect of aqueous extract of Boswellia papyrifera on ...
Amir Farshchi +3 more
doaj
Nurr1 Orchestrates Claustrum Development and Functionality
Advanced Science, EarlyView.Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan +12 more
wiley +1 more source
Generation of Educational 3D Maze Games for Carpet Handicraft in Bulgaria
Digital Presentation and Preservation of Cultural and Scientific Heritage, 2017 Serious video games applied for learning purposes play a significant and important role for the modern technology enhanced education. The paper presents an educational 3D maze video game dedicated to the development of carpet fabrication in Bulgaria ...
Boyan Bontchev, Radina Panayotova
doaj +1 more source