Results 71 to 80 of about 56,014 (312)

Astrocytic PCBP1 Suppresses Ferroptosis to Restore Glutamatergic Homeostasis and Mitigate Stress‐Induced Depression in Male Mice

Advanced Science, EarlyView.
This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang, Binbin Zhao, Min Jia, Yan Zhao, Ye Lu, Wenyu Xi, Ziyu Zhu, Xiaojuan Gong, Qingyan Ma, Yuan Gao, Yijie Guo, Pan Li, Feng Zhu, Shuguang Wei, Xiancang Ma, Yunpeng Wang   +15 more
wiley   +1 more source

Identifying Dyslexia: Link between Maze Learning and Dyslexia Susceptibility Gene, DCDC2, in Young Children. [PDF]

Dev Neurosci, 2021
Gabel LA, Voss K, Johnson E, Lindström ER, Truong DT, Murray EM, Cariño K, Nielsen CM, Paniagua S, Gruen JR.   +9 more
europepmc   +1 more source

Harnessing Time‐Dependent Magnetic Texture Dynamics via Spin‐Orbit Torque for Physics‐Enhanced Neuromorphic Computing

Advanced Science, EarlyView.
A neuromorphic computing platform using spin‐orbit torque‐controlled magnetic textures is reported. The device implements bio‐inspired synaptic functions and achieves high performance in both pattern recognition (>93%) and combinatorial optimization (>95%), enabling unified processing of cognitive and optimization tasks.
Yifan Zhang, Yu Li, Huai Lin, Xinying Wang, Long Liu, Guoliang Xing, Di Wang, Zhihao Zhao, Zhipeng Guo, Junbo Yang, Jiebin Niu, Yan Sun, Tom Wu, Guozhong Xing   +13 more
wiley   +1 more source

Neural network classification of Barnes maze search strategy utilization

Brain Research Bulletin
The Barnes maze is a commonly used test of allocentric spatial reference memory, consisting of an elevated circular table with holes around the perimeter.
Scott Ferguson, Coral Hahn-Townsend, Benoit Mouzon, Salina Yathiraj, Giovanni Brunetti, Nicole Saltiel, Cillian E. Lynch, Michael Mullan, Fiona Crawford   +8 more
doaj   +1 more source

A novel, rapidly acquired and persistent spatial memory task that induces immediate early gene expression

Behavioral and Brain Functions, 2010
Background The Morris water maze task is a hippocampus-dependent learning and memory test that typically takes between 3 days to 2 weeks of training. This task is used to assess spatial learning and induces the expression of genes known to be crucial to ...
Nalbantoglu Josephine, Shapiro Matthew L, Feldman Lisa A   +2 more
doaj   +1 more source

OPTRACE: Optical Imaging–Guided Transplantation and Tracking of Cells in the Mouse Brain

Advanced Science, EarlyView.
OPTRACE establishes an optical, two‐step platform for intracerebral cell therapy. Transparent glass pipettes enable real‐time, image‐guided delivery, while multiplex genetic labeling with two‐photon and bioluminescence readouts supports longitudinal single‐cell tracking and host–graft dynamics.
Jinghui Wang, Honglin Tan, Colleen Russell, Mikolaj Walczak, Dawei Gao, Guanda Qiao, Xiaoxuan Fan, Chengyan Chu, Miroslaw Janowski, Piotr Walczak, Yajie Liang   +10 more
wiley   +1 more source

Effect of zerumbone on scopolamine‐induced memory impairment and anxiety‐like behaviours in rats

Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2019
Introduction We investigated the effects of zerumbone (1 and 10 mg/kg) against hyperactivity, anxiety and memory impairment in scopolamine‐induced dementia in Sprague‐Dawley rats.
Sahba Jafarian, King‐Hwa Ling, Zurina Hassan, Lua Perimal‐Lewis, Mohd Roslan Sulaiman, Enoch Kumar Perimal   +5 more
doaj   +1 more source

Behavioural phenotyping, learning and memory in young and aged growth hormone-releasing hormone-knockout mice

Endocrine Connections, 2018
Background: Growth hormone-releasing hormone (GHRH) plays an important role in brain functions. The aim of this study was to examine cognitive functions and emotional behaviour in a mouse model of isolated GH deficiency due to bi-allelic ablation of the ...
Sheila Leone, Lucia Recinella, Annalisa Chiavaroli, Claudio Ferrante, Giustino Orlando, Michele Vacca, Roberto Salvatori, Luigi Brunetti   +7 more
doaj   +1 more source

Stretchable Curvature Sensors for Motion Capture with Bending‐Stretching Coupling Deformation

Advanced Science, EarlyView.
Stretchable curvature sensors based on a wavy symmetric stacked‐layer structure (WSSLS) enable decoupled bending‐stretching detection with high linearity, repeatability, and durability. Integrated into smart gloves, the sensors achieved precise motion capture and human‐robot interaction, with slip‐simulation tests demonstrating a remarkable 93.6 ...
Tairan Wang, Xinkai Xu, Shuang Li, Yuqun Lan, Kai Chen, Wei Li, Guangyuan Wang, Kuai Yu, Lijuan Sun, Yewang Su   +9 more
wiley   +1 more source

Droplet Digital CRISPR for Nucleic Acid Detection

Advanced Science, EarlyView.
This review outlines recent advances in droplet digital CRISPR technology for nucleic acid detection, combining CRISPR specificity with droplet digital‐based absolute quantification. It summarizes core principles, amplification‐assisted and amplification‐free strategies, and representative DNA and RNA biomarker applications.
Yang Zhang, Roy S. K. Walker, Anwar Sunna, Tracie J. Barber, Ming Li   +4 more
wiley   +1 more source