Results 141 to 150 of about 2,496 (195)

Mazindol in the Control of Micturition

British Journal of Urology, 1983
Summary— The appetite suppressant mazindol has been compared with a placebo in the control of incontinence in a double‐blind cross‐over trial. Twenty‐five patients were entered; 4 were withdrawn for protocol violations.
C R, Woodhouse, R C, Tiptaft
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Solvolysis of a Substituted Imidazoline, Mazindol

Journal of Pharmaceutical Sciences, 1975
Hydrolysis of mazindol to form 2-(2-aminoethyl)-3-(p-chlorophenyl)-3-hydroxyphthalimidine was followed spectro-photometrically in aqueous solutions at temperatures between 37 and 70degree, pH values up to 7.6, and an ionic strength of 0.2. The effects of acetate, formate, and phosphate buffers as well as ionic strength on the observed rate constants ...
H V, Maulding, P, Turi, D, Grossman, J P, Nazareno   +3 more
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Structure Determination of the Anorexic Agent Mazindol

Journal of Pharmaceutical Sciences, 1975
The anorexic agent mazindol was shown to exist as the carbinolamine tautomer 5-p-chlorophenyl-2,3-dihydro-5H-imidazol[2,1-a]isoindol-5-ol in solution and in the solid state. The latter was established by diffuse UV reflectance spectroscopy.
S, Barcza, W J, Houlihan
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The anorectic action of mazindol

Irish Journal of Medical Science, 1978
Mazindol is an example of a nonphenylethylamine compound which nevertheless exhibits a biochemical and behavioural profile similar to that of damphetamine. Pharmacological analysis has implicated a possible role for dopaminergic mediation in the reduction of food-intake produced by mazindol. However, side-effects, including changes in general locomotor
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Interaction of mazindol with alcohol in mice

Addiction Biology, 1996
AbstractCombined anorectic‐alcohol misuse is a prevalent problem in Brazil. In order to understand better the interactive effects of ethanol (EtOH) and mazindol (MZ), we examined the effects of EtOH (1.2 g/kg) and MZ (5.0 mg/kg) given alone or in combination, on mouse behaviour.
M S, Gevaerd, R N, Takahashi
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Synthesis of tritium labeled mazindol

Journal of Labelled Compounds and Radiopharmaceuticals, 1976
AbstractMazindol was labeled with tritium in the 6,9 positions in low yield starting with dimethyl phthalate‐3,6‐3H which was prepared by reduction of dimethyl 3‐chlorophthalate with tritium gas using 10% palladium on charcoal as a catalyst. The labeled dimethyl phathalate was hydrolisized with extensive loss of the label by exchange and after ...
Harry A. Dugger, Kenrick C. Tabot
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MAZINDOL

Medical Journal of Australia, 1980
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Extra-anorectic actions of mazindol.

Israel journal of medical sciences, 1989
In the search for mechanisms supporting the weight-reducing effect of mazindol, we examined the influence of the drug on metabolism and gastric evacuation in two groups of 10 women each. In the first group the effect of mazindol on thermogenesis was assessed by indirect calorimetry, and blood glycerol concentration was taken as an index of lipolysis ...
K, Jonderko, C, Kucio
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Mazindol (teronac) - another anorectic drug

Drug and Therapeutics Bulletin, 1974
Obesity, its management, and anorectic drugs, have been discussed previously.1 In general our conclusion was and still is that anorectic drugs are better avoided where possible. The success of any weight-reducing regimen depends on reduction of calorie intake: anorectics can help the patient to accept the diet.
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Mazindol

2021
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