Results 91 to 100 of about 50,215 (225)

Preparation and preclinical evaluation of 18F-labeled folate-RGD peptide conjugate for PET imaging of triple-negative breast carcinoma

open access: yesEJNMMI Radiopharmacy and Chemistry
Background Simultaneous targeting of RGD and FA receptors on breast carcinoma could improve the diagnostic outcome of breast cancer patients. In this study, we have designed and synthesized an FA-RGD heteromeric targeting vector, with both RGD and FA ...
Subhani M. Okarvi, Yousef Maliki
doaj   +1 more source

Neoplastic Risk in Patients With Klinefelter Syndrome

open access: yesAndrology, EarlyView.
ABSTRACT Background Besides gonadal involvement (hypogonadism, male factor infertility, and testicular hypotrophy), patients with Klinefelter syndrome (KS) may suffer from several extra‐gonadic complications, including neoplastic events. Objective The aim of this review is to summarize all major clinical evidence dealing with the association between KS
Andrea Graziani   +4 more
wiley   +1 more source

Novel N-(Substituted) Thioacetamide Quinazolinone Benzenesulfonamides as Antimicrobial Agents

open access: yesInternational Journal of Nanomedicine, 2020
Mostafa M Ghorab,1 Ali S Alqahtani,2,3 Aiten M Soliman,1 Ahmed A Askar4 1Department of Drug Radiation Research, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority (EAEA), Cairo 11765, Egypt; 2Medicinal ...
Ghorab MM   +3 more
doaj  

Midwifery Students' Definitions of Normal Labor and Birth: A Study From Five Countries

open access: yesBirth, EarlyView.
The image brings together the seven aspects considered most important in defining ‘normal/physiological birth’ according to research carried out among 664 student midwives across five countries. ABSTRACT Introduction Internationally, many women and birthing people are receiving maternity care interventions as a routine with no medical indication for ...
International Network Exploring Midwifery Students' Confidence in Physiological Birth   +12 more
wiley   +1 more source

Surveillance patterns in non‐muscle‐invasive bladder cancer across risk groups: a real‐world analysis

open access: yesBJU International, EarlyView.
Objective To provide insight into real‐world surveillance practices for patients with low‐risk (LR), intermediate‐risk (IR), and (very) high‐risk (HR) non‐muscle invasive bladder cancer (NMIBC). Patients and Methods Cystoscopy surveillance patterns were analysed using real‐world data from two population‐based cohort studies in the Netherlands ...
Lisa M. C. van Hoogstraten   +6 more
wiley   +1 more source

The effect of seawater hardness on cotton fabric dyeing using reactive blue dye

open access: yesColoration Technology, EarlyView.
Abstract Oceans are an abundant source of water; their economic potential has not yet been fully exploited. In this context, the current study aims to apply seawater in the dyeing of cotton fabrics, evaluating the influence that total hardness has on the process results.
Iêda Letícia de Souza Ferreira   +5 more
wiley   +1 more source

Phenotypes and clinical outcomes in children with moderate‐to‐severe atopic dermatitis across diverse ancestries: a Spanish multicenter observational study and cluster analysis (AD‐SKINS Project)

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives Atopic dermatitis (AD) has a highly variable clinical phenotype and ancestry can contribute to this heterogeneity. This study aims to identify clinical phenotypes of AD in children from diverse ancestry groups, evaluate clinical outcomes and response to treatment, and define phenotypic clusters with potential relevance.
Eugeni Prat‐Colilles   +21 more
wiley   +1 more source

Hamman's crunch—A pathognomonic sign of pneumomediastinum

open access: yesEquine Veterinary Education, EarlyView.
Summary Pneumomediastinum, particularly spontaneous pneumomediastinum, is uncommon and presents a diagnostic challenge. In human medicine, auscultation of Hamman's crunch, a crepitant, crunching noise, audible over the cardiac region in synchrony with the heartbeat, is considered pathognomonic for pneumomediastinum.
S. McCullagh   +4 more
wiley   +1 more source

Role of human RNase 7 in neuronal and glial cell models: moving towards an unexpected new functional link

open access: yesThe FEBS Journal, EarlyView.
Human RNase 7 is known to exert antimicrobial activity in epithelial tissues. Here, using SH‐SY5Y and U‐87 MG, neuroblastoma and glioblastoma cell lines, respectively, we found that RNase 7 enhances immune responses to LPS stimulation by reducing the expression of pro‐inflammatory cytokines, nitric oxide, and ROS.
Rosanna Culurciello   +9 more
wiley   +1 more source

Mechanistic insights into HapC: A key enzyme in prodiginine biosynthesis in Hahella chejuensis

open access: yesThe FEBS Journal, EarlyView.
HapC catalyzes prodiginine biosynthesis through coordinated movements of its ATP‐binding, substrate‐binding, and catalytic‐swivel domains. The enzyme shows tolerance toward short‐chain MAP analogs, and docking analyses reveal key residues and structural features underlying its substrate flexibility.
Yueh‐Te Chan   +10 more
wiley   +1 more source

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