Results 111 to 120 of about 51,336 (238)

Payload‐Based Clinical Pharmacology Review of Approved Antibody–Drug Conjugates: Commonalities and Considerations for Streamlined Development

Clinical Pharmacology &Therapeutics, Volume 120, Issue 3, Page 614-638, September 2026.
Antibody–drug conjugates (ADCs) combine the specificity of an antibody with the potency of a cytotoxic drug. Thirteen ADCs, utilizing seven unique cytotoxic payloads and targeting 11 distinct antigens, are currently approved by the US Food and Drug Administration as of June 2025, representing a rapidly growing and highly promising class of anticancer ...
Sijie Lu, Qingqing Xiao, Lixuan Qian, Siyuan Sun, Zhu Zhou, Michael Z. Liao, Chunze Li   +6 more
wiley   +1 more source

Management of HER2+ Breast Cancer with and without Brain Metastases in Saudi Arabia: Literature Insights and an Expert Survey of Current Practices. [PDF]

Breast Cancer (Dove Med Press)
Kullab S, Refae A, Altwairgi A, Abusanad A, Elsamany S, Abdelhafiez NA, Basulaiman B, Zahralliyali A, Alshangiti AA, Al-Mubarak M, Alwbari A, Alharbi A, Osman A, Kiwan H, Alaklabi S.   +14 more
europepmc   +1 more source

Conservation Agriculture Improves Soil Resilience by Integrating Physical, Chemical, and Biological Pathways

Global Change Biology Communications, Volume 1, Issue 3, September 2026.
Conservation agriculture significantly enhances soil resilience in tropical agroecosystems, especially in semiarid areas characterized by high degradation susceptibility, mostly related to the occurrence of shallow soils and increasing climate stress.
Luiz Diego Vidal Santos, Francisco Sandro Rodrigues Holanda, Emersson Guedes da Silva, Renisson Neponuceno de Araújo Filho, Mateus Barbosa Santos da Silva, Eliana Midori Sussuchi, Wandson dos Santos de Almeida, Jémison Mattos dos Santos   +7 more
wiley   +1 more source

The introduction of measurement-based care for patients with schizophrenia may improve psychiatric symptoms and guideline adherence rate. [PDF]

Int J Neuropsychopharmacol
Mori K, Matsumoto J, Ito S, Fukumoto K, Inada K, Kodaka F, Takano H, Kito S, Hashimoto R.   +8 more
europepmc   +1 more source

Simulated elephant foraging alters tree root exudation rates: Species‐specific responses and implications for belowground carbon dynamics in tropical forests

PLANTS, PEOPLE, PLANET, Volume 8, Issue 5, Page 1733-1745, September 2026.
Asian elephants play crucial roles in ecosystem functioning, and their interactions with plants influence above‐ and belowground carbon cycling. We tested whether their mechanically destructive foraging triggers short‐term, stress‐induced shifts in tree root exudation, an underappreciated pathway linking herbivory to belowground carbon processes.
Pratibha Khatri, Bimal Sharma, Lisa Ong, Ahimsa Campos‐Arceiz   +3 more
wiley   +1 more source

Sustained chlorhexidine susceptibility in clinical MRSA isolates despite recent exposure. [PDF]

JAC Antimicrob Resist
Morello N, Andreoni F, Staiger WI, Scheier TC, Weller D, Vostokova E, Brugger SD.   +6 more
europepmc   +1 more source

Biogenic Iron Oxide Nanoparticles Confer Induced Pre‐sowing Drought Tolerance in Glycine max via Enhanced Soil‐Plant Physiological Responses

Journal of Sustainable Agriculture and Environment, Volume 5, Issue 3, September 2026.
ABSTRACT Drought stress severely affects soybean (Glycine max L.) growth and productivity by disrupting physiological and metabolic processes. This study evaluated the potential of biogenic iron oxide nanoparticles green synthesised using Pistacia khinjuk L. leaf extract to improve soybean tolerance to water deficit.
Usman Shafqat, Awais Maqsood, Farasat Haider, Ali Raza Kashif, Basit Ali Khan, Abdullah K. Alanazi, Roberto Rodriguez‐Ramirez, Basit Ali   +7 more
wiley   +1 more source

Characteristics, treatment and survival in de novo and metachronous metastatic breast cancer: a nationwide comparative analysis. [PDF]

Breast Cancer Res Treat
Slotman E, de Munck L, Jager A, Honkoop AH, Siemerink EJM, Heijns JB, van der Wall E, Raijmakers NJH, Fransen HP, Siesling S.   +9 more
europepmc   +1 more source

Patient‐reported outcomes for monitoring substance use treatment: A systematic review of single‐item measures

Addiction, Volume 121, Issue 9, Page 2292-2316, September 2026.
Abstract Background and aims Measurement‐based care (MBC) is a structured approach using standardized, repeated assessments to monitor treatment progress and guide clinical decision‐making. MBC improves outcomes for substance use treatment but can be time consuming due in part to lengthy assessment tools. Single‐item, patient‐reported outcome measures (
Thomas J. Reese, Hilary A. Tindle, Justin Bachmann, Adam Wright, Jessica S. Ancker, Carolyn M. Audet, Mauli V. Shah, Bryan D. Steitz, Michael H. Levin, Kristopher A. Kast, David Marcovitz, Amanda von Horn, A. Taylor Kelley, John F. P. Bridges   +13 more
wiley   +1 more source

Examining Real-World Implementation of Measurement-Based Care and its Influence on Emergency Department Visit Risk Among Outpatients With Mood and Anxiety Disorders. [PDF]

Adm Policy Ment Health
Breitzig MT, Rackoff GN, Barrett TS, Shergill A, Kong L, Newman MG, Saunders EFH, Liu G.   +7 more
europepmc   +1 more source