Efficacy and Toxicity of CDK4/6 Inhibitors in Early and Metastatic HR+/HER2- Breast Cancer: An Updated Meta-Analysis of Phase III Trials. [PDF]
Dhanoa RK +3 more
europepmc +1 more source
Rosa damascena flowers, buds, leaves, branches, and hydrodistillation by‐products were investigated using FTIR‐ATR, LC–MS/MS, and a series of biological assays. The integrated approach highlighted the chemical diversity and bioactive potential of both plant materials and industrial processing residues, supporting their sustainable valorization ...
Burak Bayrak +11 more
wiley +1 more source
Characteristics, treatment and survival of older patients with metastatic triple negative breast cancer from the ESME mBC real-world national cohort: a comparison with younger women. [PDF]
Mairé M +18 more
europepmc +1 more source
PKMYT1 in Cancer: Beyond Cell Cycle Checkpoints to Context‐Dependent Therapeutic Vulnerability
ABSTRACT PKMYT1 has emerged as a promising therapeutic target distinguished by its tumor‐selective expression and essential role in replication stress management. Unlike WEE1, PKMYT1 is dispensable in normal cell cycles but critical for cancer cells coping with DNA damage, establishing a broad therapeutic window.
Lingxi Li +5 more
wiley +1 more source
A Patient-Led Survey of Antibody Drug Conjugate Usage and Dosing for People Living With Metastatic Breast Cancer. [PDF]
Beumer A +15 more
europepmc +1 more source
ABSTRACT Background Cutaneous adnexal carcinomas are a very rare group of cancers arising from appendageal structures of the skin. More than half occur in the head and neck region. No standard treatments exist for metastatic disease. Methods A 48‐year‐old postmenopausal female presented with an enlarging scalp lesion.
Nilesh Kapoor +3 more
wiley +1 more source
Mun-Hwan No, Sun-Hwa Han
openaire +1 more source
Characteristics and outcomes of patients with HER2-negative metastatic breast cancers with low expression of estrogen and progesterone receptors in the multicenter ESME cohort. [PDF]
Alexandre M +19 more
europepmc +1 more source
Multiple myeloma: A tale of deregulated transcription factors
Abstract A comprehensive understanding of the molecular mechanisms underlying multiple myeloma (MM) pathogenesis is essential for developing therapeutic strategies that overcome disease heterogeneity and treatment relapse. In this review, we focus on transcription factors (TFs), key regulators of gene expression that play critical roles in normal ...
Nahia Gómez‐Echarte +5 more
wiley +1 more source
Bipolar disorder measurement-based care: Two-phase trial in primary care. [PDF]
Cerimele JM +5 more
europepmc +1 more source

