Results 41 to 50 of about 50,215 (225)

In‐line Raman spectroscopy real‐time glucose prediction method for commercial pneumococcal vaccine drug substance fermentation manufacturing process control

Biotechnology Progress, EarlyView.
Abstract Traditional off‐line analysis methods to quantify residual metabolite concentrations in a drug substance fermentation process consume valuable time, require costly resources, and demand potentially hazardous manual operations when working with pathogenic biological organisms.
Griffin P. Thomas, Brian C. Marks, Barbara B. Alvarado‐Hernandez, Matthew Woodling, James O'Connor, Roberto Ortiz, John Higgins, Jon Shanter   +7 more
wiley   +1 more source

MBC stimulation

, 2017
memory B cells (MBC) was stimulated by influenza viruses and produce specific antibodies.
openaire   +1 more source

Antibacterial and antifungal activities of Moroccan wild edible plants selected based on ethnobotanical evidence

Roczniki Panstwowego Zakladu Higieny
Background Despite the extensive literature focusing on identifying novel antimicrobials of plant origin, little work has been undertaken to examine the antimicrobial activity of wild edible plants.
Abdelghani Aboukhalaf, Youssef Lahlou, Adil Kalili, Sara Moujabbir, Jamila Elbiyad, Belkassem El Amraoui, Rekia Belahsen   +6 more
doaj   +1 more source

Engineering Biochar‐Derived Functional Materials for High‐Performance Supercapacitors: Design Principles, Mechanisms, and Scalable Strategies

Carbon Energy, EarlyView.
ABSTRACT Biochar has emerged as a useful and adaptable source of carbon for supercapacitor electrodes. Its value comes from the way biomass chemistry, thermal conversion, and activation conditions shape the resulting pore network, surface groups, and degree of carbon ordering.
Soumen Mandal, Avinash C. Mendhe, Mayna Roy, Neha S. Barse, Taejoon Park, Han‐Seung Lee, Haigun Lee   +6 more
wiley   +1 more source

Association of an Early Resistance Genomic State With Early Progression Following CDK4/6 Inhibitor Therapy in HR+/HER2− Metastatic Breast Cancer

Cancer Nexus, EarlyView.
ABSTRACT CDK4/6 inhibitors combined with endocrine therapy are the standard first‐line treatment for hormone receptor‐positive (HR+) HER2‐negative metastatic breast cancer. However, a substantial proportion of patients experience early disease progression in routine practice. Clinicians currently lack practical tools at treatment initiation to identify
Mobina Shrestha, Salina Dahal, Vishal Mandal, Amir Babu   +3 more
wiley   +1 more source

Payload‐Based Clinical Pharmacology Review of Approved Antibody–Drug Conjugates: Commonalities and Considerations for Streamlined Development

Clinical Pharmacology &Therapeutics, EarlyView.
Antibody–drug conjugates (ADCs) combine the specificity of an antibody with the potency of a cytotoxic drug. Thirteen ADCs, utilizing seven unique cytotoxic payloads and targeting 11 distinct antigens, are currently approved by the US Food and Drug Administration as of June 2025, representing a rapidly growing and highly promising class of anticancer ...
Sijie Lu, Qingqing Xiao, Lixuan Qian, Siyuan Sun, Zhu Zhou, Michael Z. Liao, Chunze Li   +6 more
wiley   +1 more source

CSR Disclosure and Operating Performance in the Agri‐Food Manufacturing Industry: Evidence From Southern Europe

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study explores the relationship between corporate social responsibility (CSR) disclosure and operating profitability in the agri‐food manufacturing industry of Southern Europe, focusing on Extremadura (Spain). From an initial pool of 284 firms, the final sample comprised 185 companies after excluding inactive or non‐reporting cases.
Ángel Sabino Mirón Sanguino, Maria Pache Durán, Triana Arias Abelaira, María Beatriz Corchuelo Mártinez Azua   +3 more
wiley   +1 more source

Natural history of SPTBN4-related neurodevelopmental disorder with hypotonia, neuropathy, and deafness

Orphanet Journal of Rare Diseases
Background Pathogenic variants in SPTBN4 have been linked to autosomal recessive “neurodevelopmental disorder with hypotonia, neuropathy, and deafness” (MIM# 617519) known as NEDHND.
Hanan AlQudairy, Mohammad A. AlMuhaizea, Mohamed Tohary, Maissa Alfuraih, Aisha Alnafisah, Aljouhra AlHargan, Anoud Albader, Hadeel Jaber, Rawan Almass, Albandary Albakheet, Terfa Alsheddi, Eman AlObeid, Maha M. Alrasheed, Ali Al-Odaib, Hamad AlZaidan, Moeenaldeen D. AlSayed, Namik Kaya   +16 more
doaj   +1 more source

Secretopathies emerge as a new class of neurocristopathies

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira, Cassandra Millet‐Boureima, Joshua A. Moore, Loydie A. Jerome‐Majewska   +3 more
wiley   +1 more source

Antibacterial Effects of 59 Chinese Medicines Against Pathogens from Micropterus salmoides in vitro

Guangdong nongye kexue
【Objective】In order to establish a scientific foundation for the prevention and management of diseases in largemouth bass (Micropterus salmoides) culture, the objective of this study is to examine the in vitro antibacterial effects of 59 Chinese ...
Meizhen SU, Caijuan LI, Xianhua OUYANG, Aiying LEI, Guixiang TONG, Shuiping WEN, Wei LIAO, Fuyan CHEN   +7 more
doaj   +1 more source