Results 51 to 60 of about 51,336 (238)

Preparation and preclinical evaluation of 18F-labeled folate-RGD peptide conjugate for PET imaging of triple-negative breast carcinoma

EJNMMI Radiopharmacy and Chemistry
Background Simultaneous targeting of RGD and FA receptors on breast carcinoma could improve the diagnostic outcome of breast cancer patients. In this study, we have designed and synthesized an FA-RGD heteromeric targeting vector, with both RGD and FA ...
Subhani M. Okarvi, Yousef Maliki
doaj   +1 more source

Microbiome‐mediated plant‐soil feedbacks as a tool for resilient agriculture

iMetaOmics, EarlyView.
Translating plant‐soil feedbacks (PSFs) into reliable agricultural management requires shifting from input‐dependent practices toward endogenous, process‐driven crop resilience. To bridge this gap, we propose a predictive framework centered on three strategic interventions: engineering the crop holobiont, diversifying the soil habitat, and deploying ...
Muhammad Asif, Hazrat Bilal, Min Xiao, Lei Dong, Wen‐Jun Li   +4 more
wiley   +1 more source

Europe's contribution to the evaluation of the use of systemic antimicrobials in the treatment of periodontitis

Periodontology 2000, EarlyView., 2023
Abstract This narrative review celebrates Europe's contribution to the current knowledge on systemically administered antimicrobials in periodontal treatment. Periodontitis is the most frequent chronic noncommunicable human disease. It is caused by dysbiotic bacterial biofilms and is commonly treated with subgingival instrumentation.
David Herrera, Arie Jan van Winkelhoff, Paula Matesanz, Katalina Lauwens, Wim Teughels   +4 more
wiley   +1 more source

A synthetic community promotes macadamia growth via root‐microbe interactions and systemic plant responses

iMetaOmics, EarlyView.
We employed an 18‐month pot experiment and an integrated multi‐omics approach to elucidate the potential mechanisms underlying synthetic community (SynCom)‐mediated macadamia growth promotion. SynCom inoculation enhanced soil nitrogen cycling and potential nutrient (e.g., iron) acquisition.
Xiaofang Yao, Qiumei Liu, Wenlin Wang, Qiujin Tan, Chunheng Zhou, Dejun Li   +5 more
wiley   +1 more source

Eugenoplatin (a phyto-chemo drug conjugate) targets cancer stem cells through inhibition of the β-catenin signaling in triple-negative breast cancer cells

Journal of Translational Medicine
Background Breast cancer is the most prevalent and leading cause of cancer-related mortality among women worldwide. The triple-negative subtype, the most aggressive form of the disease, is associated with the poorest prognosis.
Noura N. Alraouji, Basem Al-Otaibi, Mohd Yasir Khan, Falah Al-Mohanna, Amer Al-Mazrou, Taher Al-Tweigeri, Ibrahim Al-Jammaz, Ayodele A. Alaiya, Mohammed Cherkaoui, Abdelilah Aboussekhra   +9 more
doaj   +1 more source

Statistical Downscaling of Daily Temperature and Precipitation From Regional Climate Models in Complex Mountain Terrain

International Journal of Climatology, EarlyView.
The study provides insights for post‐processing climate model output in complex terrain, useful for climate change impact models. We compared different bias adjustment and downscaling techniques from quantile delta mapping to simple lapse rates. We developed a new spatial downscaling method based on principal components analysis, which showed superior ...
Michael Matiu, Anna Napoli, Alberto Bellin, Dino Zardi, Bruno Majone   +4 more
wiley   +1 more source

Antibacterial Effects of 59 Chinese Medicines Against Pathogens from Micropterus salmoides in vitro

Guangdong nongye kexue
【Objective】In order to establish a scientific foundation for the prevention and management of diseases in largemouth bass (Micropterus salmoides) culture, the objective of this study is to examine the in vitro antibacterial effects of 59 Chinese ...
Meizhen SU, Caijuan LI, Xianhua OUYANG, Aiying LEI, Guixiang TONG, Shuiping WEN, Wei LIAO, Fuyan CHEN   +7 more
doaj   +1 more source

The relationship between coronary artery calcification and myocardial perfusion in asymptomatic women

Annals of Saudi Medicine, 2012
BACKGROUND AND OBJECTIVES: No data are available in Saudi Arabia on the relationship between coronary artery calcification (CAC) and myocardial perfusion scintigraphy (MPS) in asymptomatic women, for determining subclinical coronary artery disease (CAD).
Ahmed Fathala, Ali Al Amer, Mohamed Shukri, Mohei M. Abouzied, Abdulaziz Alsugair   +4 more
doaj   +1 more source

Gas chromatography–mass spectrometry analysis and comprehensive evaluation of antibacterial, antioxidant and anti‐inflammatory properties of Thymus capitatus extracts from Libya

JSFA reports, EarlyView.
Abstract Background The emergence of multidrug‐resistant bacteria necessitates the development of alternative therapeutic approaches. Thymus capitatus, a Mediterranean medicinal plant, has been traditionally used to treat various ailments, but its bioactive potential from Libyan origins remains underexplored.
Ahmed Saeed Kabbashi, Taher Issa Shailabi, Ahlam Mohamed Keshar, Amel Mahmoud Abdrabo, Ahmed Ali Mustafa, Bushray Salih Jabullah, Rama Burhan Hasan, Mona Rafea Mosa, Esraa Radwan Ibrahim, Maryam Mohammed Ibrahim   +9 more
wiley   +1 more source

Simulated Root Exudation Gradient Reveals Dosage‐Dependent Carbon Sequestration in Desertification Ecosystems

Land Degradation &Development, EarlyView.
ABSTRACT Root exudates serve as a key driver for the restoration of soil organic carbon (SOC), particularly in aeolian desertification ecosystems where aboveground litter retention is limited. While Salix cupularis is widely planted as an effective pioneer shrub for ecological rehabilitation on the Qinghai‐Tibet Plateau, how the quantity of its root ...
Ran Xue, Xuemei Fang, Dongming Chen, Fei Yan, Aomei Jia, Zhouwen Ma, Yongheng Gao, Jiqiong Zhou, Jian Zhang, Lin Liu   +9 more
wiley   +1 more source