Results 91 to 100 of about 108,579 (365)

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

Detección Fenotípica de Carbapenemasas en Pseudomonas aeruginosa en Pacientes que acudieron al Hospital de Clínicas San Lorenzo de febrero a julio 2013

Memorias del Instituto de Investigaciones en Ciencias de la Salud, 2016
Pseudomonas aeruginosa es uno de los patógenos oportunistas más importantes, causante de infecciones, con alto índice de morbi-mortalidad. Los carbapenemes son antibióticos que poseen un amplio espectro de actividad y son altamente potentes, que los ...
Clotilde Ophelie Marie Molin Queste
doaj  

Prevalence of Extended-spectrum Beta-lactamase (ESBL), Metallo Beta-lactamase (MBL) and Carbapenemase Producing Acinetobacter Species Isolated from Various Clinical Samples in Tertiary Care Hospital

Journal of Pure and Applied Microbiology
Acinetobacter is an important nosocomial pathogen causing health care associated infections. It is highly antibiotic resistant gram-negative bacilli. The study was done to determine the prevalence of Acinetobacter species isolated from various clinical ...
Manasi Vikas Yadav, Geeta S. Karande, S.N. Karande, S.R. Patil, Shanu Sharma   +4 more
doaj   +1 more source

Antimicrobial peptide LL-37 and recombinant human mannose-binding lectin express distinct age- and pathogen-specific antimicrobial activity in human newborn cord blood in vitro [PDF]

, 2018
Background: There is a need to prevent and treat infection in newborns. One approach is administration of antimicrobial proteins and peptides (APPs) such as LL-37, a membrane-active cathelicidin antimicrobial peptide, and mannose-binding lectin (MBL), a ...
Borriello, Francesco, Jeffers, Carleen, Joshi, Sweta, Levy, Ofer, Li, Ning, Ozonoff, Al, Pettengill, Matthew, Scheid, Annette   +7 more
core   +1 more source

Quantum Mutual Information as a Probe for Many-Body Localization

, 2016
We demonstrate that the quantum mutual information (QMI) is a useful probe to study many-body localization (MBL). First, we focus on the detection of a metal--insulator transition for two different models, the noninteracting Aubry-Andr\'e-Harper model ...
Bardarson, Jens H., Bera, Soumya, De Tomasi, Giuseppe, Pollmann, Frank   +3 more
core   +1 more source

Antiemesis Corticosteroids Potentiate Checkpoint Blockade Efficacy by Normalizing the Immune Microenvironment in Metastatic Murine Breast Cancer

Advanced Science, EarlyView.
Corticosteroids improve the efficacy of immune checkpoint blockade therapy in metastatic murine breast cancer. By normalizing the tumor immune microenvironment, corticosteroids reduce immunosuppressive signals, restore T‐cell function, and promote antitumor immune responses, resulting in enhanced tumor control.
John D. Martin, Koji Nagaoka, Myrofora Panagi, Akihiro Hosoi, Fotios Mpkeris, Pengwen Chen, Thahomina T. Khan, Margaret R. Martin, Changbo Sun, Chrysovalantis Voutouri, Maria Louca, Panagiotis Papageorgis, Akira Sumiyoshi, Nobuhiro Nitta, Kazuyoshi Takeda, Ichio Aoki, Kazunori Kataoka, Triantafyllos Stylianopoulos, Kazuhiro Kakimi, Horacio Cabral   +19 more
wiley   +1 more source

Many-body localization phase transition: A simplified strong-randomness approximate renormalization group

, 2016
We present a simplified strong-randomness renormalization group (RG) that captures some aspects of the many-body localization (MBL) phase transition in generic disordered one-dimensional systems.
Devakul, Trithep, Huse, David A., Zhang, Liangsheng, Zhao, Bo   +3 more
core   +1 more source

The salivary scavenger and agglutinin binds MBL and regulates the lectin pathway of complement in solution and on surfaces

Front. Immun., 2012
The salivary scavenger and agglutinin (SALSA), also known as gp340, salivary agglutinin and deleted in malignant brain tumor 1, is a 340-kDa glycoprotein expressed on mucosal surfaces and secreted into several body fluids.
M. Reichhardt, V. Loimaranta, S. Thiel, J. Finne, S. Meri, H. Jarva   +5 more
semanticscholar   +1 more source

Evaluation of inhibitor-combination mCIM for detecting MBL-producing Enterobacterales using three MBL inhibitors

Journal of Medical Microbiology, 2019
The increase in carbapenemase-producing Enterobacterales (CPE), including metallo-β-lactamase (MBL) producers, is a severe global health concern. Thus, highly sensitive and specific methods for detecting MBL producers are needed. In this study, we tested the detectability of MBL-producing Enterobacterales against three types of MBL inhibitors (sodium ...
Kageto Yamada, Masakazu Sasaki, Waka Imai, Hinako Murakami, Toshisuke Morita, Kotaro Aoki, Yoshikazu Ishii, Kazuhiro Tateda   +7 more
openaire   +2 more sources

Relationship between gene polymorphisms of mannose‐binding lectin (MBL) and two molecular forms of MBL [PDF]

European Journal of Immunology, 2003
Abstract Mannose‐binding lectin (MBL) activates complement through MBL‐associated serine proteases (MASP). A deficiency in MBL due to mutations at exon 1 of the human MBL gene is reported to cause vulnerability to infection. We examined sera of known MBL genotype by gel filtration and assessed their elution patterns using an ELISA for
Itaru, Terai, Kunihiko, Kobayashi, Masanao, Matsushita, Hiroshi, Miyakawa, Naoki, Mafune, Hideaki, Kikuta   +5 more
openaire   +2 more sources