Results 181 to 190 of about 55,808 (260)

The Maintenance of Dysmyelinated Small‐Diameter Axons by 14‐3‐3s in the Central Nervous System

open access: yesGlia, Volume 74, Issue 11, November 2026.
Dysmyelinated small‐diameter axons are maintained in teneurin‐4 deficient mice at the age of 1 year, while axonal damage is observed. 14‐3‐3s are highly expressed and suppress the progression of the damage in these axons. ABSTRACT In the central nervous system, myelin formed around nerve axons by oligodendrocyte enables efficient conduction of action ...
Nanako Yamada   +15 more
wiley   +1 more source

Clinical Characterization of Enzyme and Transporter Precipitants to Evaluate Drug–Drug Interactions for Orforglipron, a Small Molecule Glucagon‐Like Peptide‐1 Receptor Agonist

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 979-990, October 2026.
Orforglipron is an orally administered, small‐molecule glucagon‐like peptide‐1 receptor agonist in clinical development for the treatment of type 2 diabetes and obesity. Orforglipron is a substrate of CYP3A4, organic anion transporting polypeptides (OATPs) 1B/1B3, and P‐glycoprotein (P‐gp); however, precipitants commonly used to define these mechanisms
Bridget L. Morse   +7 more
wiley   +1 more source

Effect of Vaping on Treatment Outcomes in Patients With Gingivitis, Periodontitis, and/or Peri‐Implant Disease: A Systematic Review

open access: yesClinical and Experimental Dental Research, Volume 12, Issue 5, October 2026.
ABSTRACT Objective This systematic review aimed to evaluate the effect of vaping on periodontal treatment outcomes for patients with gingivitis, periodontitis, and/or peri‐implant disease. Material and Methods An electronic database search was conducted using Ovid MEDLINE, PubMed, Scopus, and Web of Science, with no date restrictions.
Stacey May Gould   +6 more
wiley   +1 more source

Malassezia May Contribute to Basal Cell Carcinoma Development via Inflammatory and Oxidative Stress Pathways

open access: yesMicrobiologyOpen, Volume 15, Issue 5, October 2026.
Malassezia (predominantly M. globosa) colonizes BCC tissues. In vitro fungal stimulation accelerates epithelial proliferation and modulates inflammatory/oxidative stress cascades potentially relevant to BCC biology. ABSTRACT Basal cell carcinoma (BCC) is the most common malignant skin tumor.
Xiaolei Zhu   +5 more
wiley   +1 more source

Glycoproteomic Signatures of IgG Subclass N‐Glycosylation Reveal Molecular Endotypes in Idiopathic Inflammatory Myopathies

open access: yesMedComm, Volume 7, Issue 10, October 2026.
• EThcD‐sceHCD‐MS/MS and updated PANDA software decode IgG N‐glycosylation in IIMs. • Unsupervised clustering reveals three novel glyco‐endotypes matching clinical phenotypes. • A seven‐glycopeptide model enables robust endotype prediction beyond conventional subtypes.
Tong Wu   +9 more
wiley   +1 more source

Prevalence of Peri-Implantitis Around Zirconia Implants: A Systematic Review and Meta-Analysis of Current Evidence. [PDF]

open access: yesClin Implant Dent Relat Res
Moraschini V   +7 more
europepmc   +1 more source

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