Results 1 to 10 of about 181,836 (261)

Multidrug resistant Acinetobacter

Journal of Global Infectious Diseases, 2010
Emergence and spread of Acinetobacter species, resistant to most of the available antimicrobial agents, is an area of great concern. It is now being frequently associated with healthcare associated infections.
Vikas Manchanda, Sinha Sanchaita, N P Singh   +2 more
doaj   +3 more sources

Identification of an Outbreak Cluster of Extensively Antibiotic-Resistant GC1 Acinetobacter baumannii Isolates in U.S. Military Treatment Facilities

Microbiology Spectrum, 2023
An outbreak involving an extensively antibiotic-resistant Acinetobacter baumannii strain in three military treatment facilities was identified. Fifty-nine isolates recovered from 30 patients over a 4-year period were found among a large collection of ...
Ting L. Luo, Christopher J. Harmer, Francois Lebreton, Jason Stam, Jason W. Bennett, Ruth M. Hall, Patrick T. Mc Gann   +6 more
doaj   +1 more source

A one-year genomic investigation of Escherichia coli epidemiology and nosocomial spread at a large US healthcare network

Genome Medicine, 2022
Background Extra-intestinal pathogenic Escherichia coli (ExPEC) are a leading cause of bloodstream and urinary tract infections worldwide. Over the last two decades, increased rates of antibiotic resistance in E.
Emma G. Mills, Melissa J. Martin, Ting L. Luo, Ana C. Ong, Rosslyn Maybank, Brendan W. Corey, Casey Harless, Lan N. Preston, Joshua A. Rosado-Mendez, Scott B. Preston, Yoon I. Kwak, Michael G. Backlund, Jason W. Bennett, Patrick T. Mc Gann, Francois Lebreton   +14 more
doaj   +1 more source

Detection of OXA-181-producing Pseudomonas aeruginosa in Germany

International Journal of Medical Microbiology, 2022
Objectives: To report the detection of the class D carbapenemase OXA-181 in an MDR clinical Pseudomonas aeruginosa isolate in Germany. Methods: Carbapenemase detection was performed by using several phenotypic tests such as the modified Hodge test, a ...
Jennifer Schauer, Sören G. Gatermann, Jessica Eisfeld, Jörg Hans, Niels Pfennigwerth   +4 more
doaj   +1 more source

Multidrug Resistance

Annals of Medicine, 1991
Resistance of malignant cells to cytotoxic agents is often a limiting factor to successful chemotherapy. The classical multidrug resistance is characterised by overexpression of a membrane protein, P-glycoprotein, which acts like a drug extruding pump reducing accumulation of cytotoxic agents inside malignant cells, thereby preventing their function ...
M I, Tiirikainen, T, Krusius
openaire   +4 more sources

Multidrug-resistant tuberculosis [PDF]

The Lancet, 2019
The ideal number of drugs needed and treatment duration are crucial issues in the management of multidrug-resistant tuberculosis (MDR-TB). Thus, we read with interest the Article by the Collaborative Group for the Meta-Analysis of Individual Patient Data in MDR-TB treatment–2017,1 the results of which support our proposal,2 from 2015, to classify anti ...
Bern-Thomas, Nyang'wa, Catherine, Berry, Katherine, Fielding, Andrew J, Nunn   +3 more
  +11 more sources

Multidrug resistance associated proteins in multidrug resistance [PDF]

Chinese Journal of Cancer, 2012
Multidrug resistance proteins (MRPs) are members of the C family of a group of proteins named ATP-binding cassette (ABC) transporters. These ABC transporters together form the largest branch of proteins within the human body. The MRP family comprises of 13 members, of which MRP1 to MRP9 are the major transporters indicated to cause multidrug resistance
Sodani, Kamlesh, Patel, Atish, Kathawala, Rishil J., Chen, Zhe-Sheng   +3 more
openaire   +2 more sources

Mechanisms of IS26-Mediated Amplification of the aphA1 Gene Leading to Tobramycin Resistance in an Acinetobacter baumannii Isolate

Microbiology Spectrum, 2022
Enhanced levels of resistance to antibiotics arising from amplification of an antibiotic resistance gene that impact therapeutic options are increasingly observed. Amplification can also disclose novel phenotypes leading to treatment failure.
Christopher J. Harmer, Francois Lebreton, Jason Stam, Patrick T. McGann, Ruth M. Hall   +4 more
doaj   +1 more source

An Assessment of Siderophore Production, Mucoviscosity, and Mouse Infection Models for Defining the Virulence Spectrum of Hypervirulent Klebsiella pneumoniae

mSphere, 2021
The pathogenic potential of hvKp strains is primarily mediated by a large virulence plasmid. The minimal set of genes required for the full expression of the hypervirulent phenotype is undefined.
Thomas A. Russo, Ulrike MacDonald, Sidra Hassan, Ellie Camanzo, Francois LeBreton, Brendan Corey, Patrick McGann   +6 more
doaj   +1 more source

Pseudomonas Endocarditis with an unstable phenotype: the challenges of isolate characterization and Carbapenem stewardship with a partial review of the literature

Antimicrobial Resistance and Infection Control, 2017
Background Pseudomonas endocarditis is exceedingly rare, especially in patients without predisposing risks. We present such a case that included unexpected switches in antibacterial resistance profiles in two Pseudomonas aeruginosa (PA) strains with the ...
Emil Lesho, Erik Snesrud, Yoon Kwak, Ana Ong, Rosslyn Maybank, Maryrose Laguio-Vila, Ann R. Falsey, Mary Hinkle   +7 more
doaj   +1 more source