Results 31 to 40 of about 904,396 (254)

Evaluation of a PCR-based universal heteroduplex generator assay as a tool for rapid detection of multidrug-resistant Mycobacterium tuberculosis in Peru.

, 2003
Multidrug-resistant tuberculosis is an increasing health problem worldwide, especially in developing countries. The PCR-UHG-Rif assay, which detects mutations within the rpoB gene associated with rifampin resistance, was evaluated for its ability and ...
Sonia H. Montenegro, Teresa Valencia, Luz Caviedes, Evans, Carlton A, Holger Mayta, Valencia, Teresa, Fanny Arenas, Arenas, Fanny, Montenegro, Sonia H, Ortiz, Jaime, Jaime Ortiz, Gilman, Robert H, Carlton A. Evans, Ticona, Eduardo, Robert H. Gilman, Chumpitaz, Rosa, Williams, Diana L, Tuberculosis Working Group in Perú, Eduardo Ticona, Rosa Chumpitaz, Mayta, Holger, Caviedes, Luz, Diana L. Williams   +22 more
core   +1 more source

Molecular characterization of multidrug-resistant ESKAPEE pathogens from clinical samples in Chonburi, Thailand (2017–2018)

BMC Infectious Diseases, 2022
Background ESKAPEE pathogens Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Enterobacter spp.
Sirigade Ruekit, Apichai Srijan, Oralak Serichantalergs, Katie R. Margulieux, Patrick Mc Gann, Emma G. Mills, William C. Stribling, Theerasak Pimsawat, Rosarin Kormanee, Suthisak Nakornchai, Chaiwat Sakdinava, Prawet Sukhchat, Mariusz Wojnarski, Samandra T. Demons, John M. Crawford, Paphavee Lertsethtakarn, Brett E. Swierczewski   +16 more
doaj   +1 more source

TnCentral: a Prokaryotic Transposable Element Database and Web Portal for Transposon Analysis

mBio, 2021
The ability of bacteria to undergo rapid evolution and adapt to changing environmental circumstances drives the public health crisis of multiple antibiotic resistance, as well as outbreaks of disease in economically important agricultural crops and ...
Karen Ross, Alessandro M. Varani, Erik Snesrud, Hongzhan Huang, Danillo Oliveira Alvarenga, Jian Zhang, Cathy Wu, Patrick McGann, Mick Chandler   +8 more
doaj   +1 more source

Does antibiotic prophylaxis for dental treatment prevent periprosthetic infections?

GMS Infectious Diseases
Background: The German Society for Arthroplasty (AE) recommends a single dose of 2,000 mg amoxicillin as an antibiotic prophylaxis to prevent periprosthetic joint infections (PJI) in patients with total hip or knee arthroplasty (THA, TKA) who undergo ...
Ursel Heudorf, Rolf Tessmann, Klaus-Peter Hunfeld   +2 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Detecting, mapping, and suppressing the spread of a decade-long Pseudomonas aeruginosa nosocomial outbreak with genomics

eLife
Whole-genome sequencing is revolutionizing bacterial outbreak investigation, but its application to the clinic remains limited. In 2020, prospective and retrospective surveillance detected a Pseudomonas aeruginosa outbreak with 253 isolates collected ...
William Stribling, Lindsey R Hall, Aubrey Powell, Casey Harless, Melissa J Martin, Brendan W Corey, Erik Snesrud, Ana Ong, Rosslyn Maybank, Jason Stam, Katelyn V Bartlett, Brendan T Jones, Lan N Preston, Katherine F Lane, Bernadette Thompson, Lynn M Young, Yoon I Kwak, Alice E Barsoumian, Ana Elizabeth Markelz, John L Kiley, Robert J Cybulski, Jason W Bennett, Patrick T Mc Gann, Francois Lebreton   +23 more
doaj   +1 more source

The prevalences of Salmonella Genomic Island 1 variants in human and animal Salmonella Typhimurium DT104 are distinguishable using a Bayesian approach [PDF]

, 2011
Throughout the 1990s, there was an epidemic of multidrug resistant Salmonella Typhimurium DT104 in both animals and humans in Scotland. The use of antimicrobials in agriculture is often cited as a major source of antimicrobial resistance in pathogenic ...
Matthew J Denwood, Reid, S W J, Derek J Brown, Daniel T Haydon, Mellor Dominic J., Mellor, D J, Louise Matthews, Alison E. Mather, Matthews, L., Reid Stuart W. J., Mather, A E, Haydon, D T, Derek J. Brown, Alison E Mather, John E Coia, Coia John E., Matthews, L, Mather, A.E., Stuart W J Reid, Daniel T. Haydon, Brown, D J, Denwood Matthew J., Haydon, D.T., Coia, J E, Dominic J. Mellor, Brown Derek J., John E. Coia, Coia, J.E., Reid, S.W.J., Matthew J. Denwood, Matthews Louise, Stuart W. J. Reid, Denwood, M.J., Denwood, M J, Mather Alison E., Mellor, D.J., Dominic J Mellor, Haydon Daniel T., Brown, D.J.   +38 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

High genetic relatedness between multidrug resistant bacteria before and after the 2022 invasion of Ukraine

Genome Medicine
Background The Russian invasion of Ukraine in 2022 has placed extraordinary pressure on hospitals there. One consequence of this has been the alarming increase in infections caused by multi-drug resistant organisms (MDROs), both within Ukraine and among ...
Francois Lebreton, Viacheslav Kondratiuk, Valentyn Kovalchuk, Niels Pfennigwerth, Ting L. Luo, Brendan T. Jones, Nadiia Fomina, Frieder Fuchs, Jörg B. Hans, Jessica Eisfeld, Ana Ong, Sören Gatermann, Jason W. Bennett, Patrick Mc Gann   +13 more
doaj   +1 more source

IS26-Mediated Transfer of blaNDM–1 as the Main Route of Resistance Transmission During a Polyclonal, Multispecies Outbreak in a German Hospital

Frontiers in Microbiology, 2019
One of the most demanding challenges in infection control is the worldwide dissemination of multidrug-resistant (MDR) bacteria in clinical settings. Especially the increasing prevalence of carbapenemase producing Gram-negative pathogens poses an urgent ...
Robert E. Weber, Michael Pietsch, Andre Frühauf, Yvonne Pfeifer, Maria Martin, Dirk Luft, Sören Gatermann, Niels Pfennigwerth, Martin Kaase, Guido Werner, Stephan Fuchs   +10 more
doaj   +1 more source