Results 31 to 40 of about 306,632 (271)

Molecular characterization of multidrug-resistant ESKAPEE pathogens from clinical samples in Chonburi, Thailand (2017–2018)

BMC Infectious Diseases, 2022
Background ESKAPEE pathogens Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Enterobacter spp.
Sirigade Ruekit, Apichai Srijan, Oralak Serichantalergs, Katie R. Margulieux, Patrick Mc Gann, Emma G. Mills, William C. Stribling, Theerasak Pimsawat, Rosarin Kormanee, Suthisak Nakornchai, Chaiwat Sakdinava, Prawet Sukhchat, Mariusz Wojnarski, Samandra T. Demons, John M. Crawford, Paphavee Lertsethtakarn, Brett E. Swierczewski   +16 more
doaj   +1 more source

TnCentral: a Prokaryotic Transposable Element Database and Web Portal for Transposon Analysis

mBio, 2021
The ability of bacteria to undergo rapid evolution and adapt to changing environmental circumstances drives the public health crisis of multiple antibiotic resistance, as well as outbreaks of disease in economically important agricultural crops and ...
Karen Ross, Alessandro M. Varani, Erik Snesrud, Hongzhan Huang, Danillo Oliveira Alvarenga, Jian Zhang, Cathy Wu, Patrick McGann, Mick Chandler   +8 more
doaj   +1 more source

Draft Genome Sequence of Multidrug-Resistant Abortive Campylobacter jejuni from Northern California. [PDF]

, 2017
Campylobacter jejuni is an enteric bacterium that can cause abortion in livestock. This is the release of a multidrug-resistant Campylobacter jejuni genome from an isolate that caused an abortion in a cow in northern California.
Clothier, Kristin A, Huang, Bihua C, Kong, Nguyet, Weimer, Bart C, Weis, Allison M   +4 more
core   +2 more sources

Near-ubiquitous presence of a vancomycin-resistant Enterococcus faecium ST117/CT71/vanB –clone in the Rhine-Main metropolitan area of Germany

Antimicrobial Resistance and Infection Control, 2019
Whole-genome sequencing analysis of Vancomycin-resistant Enterococcus faecium isolates from the Frankfurt metropolitan region revealed that 78/94 isolates were MLST type ST117, cgMLST complex type CT71 with a common vanB chromosomal insertion site.
Linda Falgenhauer, Moritz Fritzenwanker, Can Imirzalioglu, Katrin Steul, Marlene Scherer, Rhine-Main VREfm study group, Ursel Heudorf, Trinad Chakraborty   +7 more
doaj   +1 more source

Multidrug-resistant Mycobacterium tuberculosis, Bangui, Central African Republic [PDF]

, 2006
We investigated multidrug-resistant (MDR) Mycobacterium tuberculosis strains in Bangui, Central African Republic. We found 39.6% with the same spoligotype and synonymous single nucleotide polymorphism in the mutT1 gene.
Nouvel, Laurent-Xavier, Kassa-Kelembho, Eric, Dos Vultos, Tiago, Zandanga, Germain, Rauzier, Jean, Lafoz, Carmen, Martin, Carlos, Blazquez, Jesus, Talarmin, Antoine, Gicquel, Brigitte   +9 more
core   +2 more sources

Drug-Resistant Tuberculosis--Current Dilemmas, Unanswered Questions, Challenges and Priority Needs [PDF]

, 2012
Tuberculosis was declared a global emergency by the World Health Organization (WHO) in 1993. Following the declaration and the promotion in 1995 of directly observed treatment short course (DOTS), a cost-effective strategy to contain the tuberculosis ...
Abubakar, Ibrahim, Atun, Rifat, Chakaya, Jeremiah, Cox, Helen, Ditiu, Lucica, Ford, Nathan, Grobusch, Martin, Hoelscher, Michael, Lawn, Stephen D., Maeurer, Markus, Marais, Ben, Mchugh, Timothy D., McNerney, Ruth, Memish, Ziad, Migliori, Giovanni-Battista, Mwaba, Peter, O'Grady, Justin, Pletschette, Michel, Ramsay, Andrew, Raviglione, Mario, Schito, Marco, Squire, S. Bertel, Swaminathan, Soumya, Zumla, Alimuddin   +23 more
core   +1 more source

Detecting, mapping, and suppressing the spread of a decade-long Pseudomonas aeruginosa nosocomial outbreak with genomics

eLife
Whole-genome sequencing is revolutionizing bacterial outbreak investigation, but its application to the clinic remains limited. In 2020, prospective and retrospective surveillance detected a Pseudomonas aeruginosa outbreak with 253 isolates collected ...
William Stribling, Lindsey R Hall, Aubrey Powell, Casey Harless, Melissa J Martin, Brendan W Corey, Erik Snesrud, Ana Ong, Rosslyn Maybank, Jason Stam, Katelyn V Bartlett, Brendan T Jones, Lan N Preston, Katherine F Lane, Bernadette Thompson, Lynn M Young, Yoon I Kwak, Alice E Barsoumian, Ana Elizabeth Markelz, John L Kiley, Robert J Cybulski, Jason W Bennett, Patrick T Mc Gann, Francois Lebreton   +23 more
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

High genetic relatedness between multidrug resistant bacteria before and after the 2022 invasion of Ukraine

Genome Medicine
Background The Russian invasion of Ukraine in 2022 has placed extraordinary pressure on hospitals there. One consequence of this has been the alarming increase in infections caused by multi-drug resistant organisms (MDROs), both within Ukraine and among ...
Francois Lebreton, Viacheslav Kondratiuk, Valentyn Kovalchuk, Niels Pfennigwerth, Ting L. Luo, Brendan T. Jones, Nadiia Fomina, Frieder Fuchs, Jörg B. Hans, Jessica Eisfeld, Ana Ong, Sören Gatermann, Jason W. Bennett, Patrick Mc Gann   +13 more
doaj   +1 more source

Does antibiotic prophylaxis for dental treatment prevent periprosthetic infections?

GMS Infectious Diseases
Background: The German Society for Arthroplasty (AE) recommends a single dose of 2,000 mg amoxicillin as an antibiotic prophylaxis to prevent periprosthetic joint infections (PJI) in patients with total hip or knee arthroplasty (THA, TKA) who undergo ...
Ursel Heudorf, Rolf Tessmann, Klaus-Peter Hunfeld   +2 more
doaj   +1 more source