Results 1 to 10 of about 11,520 (179)

Antimicrobial Resistance of Hypervirulent Klebsiella pneumoniae: Epidemiology, Hypervirulence-Associated Determinants, and Resistance Mechanisms [PDF]

Frontiers in Cellular and Infection Microbiology, 2017
Klebsiella pneumoniae is one of the most clinically relevant species in immunocompromised individuals responsible for community-acquired and nosocomial infections, including pneumonias, urinary tract infections, bacteremias, and liver abscesses.
Chang-Jun Cha, Sang Hee Lee, Chang-Ro Lee   +2 more
exaly   +5 more sources

Stool Samples of Acute Diarrhea Inpatients as a Reservoir of ST11 Hypervirulent KPC-2-Producing Klebsiella pneumoniae

mSystems, 2020
The emergence and spread of carbapenem-resistant hypervirulent Klebsiella pneumoniae sequence type 11 (ST11-CR-HvKP) in China are a great concern in the public health community.
Beiwen Zheng, Hao Xu, Tao Lv, Lihua Guo, Yu Xiao, Chen Huang, Shuntian Zhang, Yunbo Chen, Huiming Han, Ping Shen, Yonghong Xiao, Lanjuan Li   +11 more
doaj   +3 more sources

Hypermucoviscosity Regulator RmpD Interacts with Wzc and Controls Capsular Polysaccharide Chain Length

mBio, 2023
Klebsiella pneumoniae is a leading cause of nosocomial infections, including pneumonia, bacteremia, and urinary tract infections. Treatment options are increasingly restricted by the high prevalence of resistance to frontline antibiotics, including ...
Olga G. Ovchinnikova, Logan P. Treat, Tanisha Teelucksingh, Bradley R. Clarke, Taryn A. Miner, Chris Whitfield, Kimberly A. Walker, Virginia L. Miller   +7 more
doaj   +1 more source

A 54‐year‐old healthy patient with meningitis and conjunctivitis

Journal of the American College of Emergency Physicians Open, 2021
We describe a case report of hypermucoviscous Klebsiella pneumoniae (KP) promptly diagnosed by blood and cerebrospinal fluid (CSF) culture with positive string test.
Gilles Troché, Amandine Henry, Florence Sarfati, Charles Hickel, Marlène Amara, Fabrice Bruneel   +5 more
doaj   +1 more source

Clinical and Bacterial Characteristics of Klebsiella pneumoniae Affecting 30-Day Mortality in Patients With Bloodstream Infection

Frontiers in Cellular and Infection Microbiology, 2021
BackgroundThere is a paucity of studies using clinical characteristics and whole-genome sequencing together to fully identify the risk factors of patients with Klebsiella pneumoniae (KP) bloodstream infection (BSI).MethodsWe retrospectively analyzed the ...
Xingbing Wu, Qingyi Shi, Shimo Shen, Chen Huang, Hongcheng Wu   +4 more
doaj   +1 more source

Molecular Investigation of Klebsiella pneumoniae from Clinical Companion Animals in Beijing, China, 2017–2019

Pathogens, 2021
This work is aimed to elucidate the prevalence and characteristics of antimicrobial resistance, virulence, and molecular typing in Klebsiella pneumoniae from clinical companion animals in Beijing, China. In total, 105 K.
Zhenbiao Zhang, Lei Lei, Haixia Zhang, Hegen Dai, Yu Song, Lei Li, Yang Wang, Zhaofei Xia   +7 more
doaj   +1 more source

Aerobactin Seems To Be a Promising Marker Compared With Unstable RmpA2 for the Identification of Hypervirulent Carbapenem-Resistant Klebsiella pneumoniae: In Silico and In Vitro Evidence

Frontiers in Cellular and Infection Microbiology, 2021
BackgroundThe incidence of hypervirulent (hv) carbapenem-resistant (CR) Klebsiella pneumoniae (Kp) is increasing globally among various clones and is also responsible for nosocomial infections.
Chaitra Shankar, Soumya Basu, Binesh Lal, Sathiya Shanmugam, Karthick Vasudevan, Purva Mathur, Sudha Ramaiah, Anand Anbarasu, Balaji Veeraraghavan   +8 more
doaj   +1 more source

Emergence of a Hypervirulent Tigecycline-Resistant Klebsiella pneumoniae Strain Co-producing blaNDM–1 and blaKPC–2 With an Uncommon Sequence Type ST464 in Southwestern China

Frontiers in Microbiology, 2022
Emergence of blaNDM–1 and blaKPC–2 co-producing Klebsiella pneumoniae strains is currently attracting widespread attention, but little information is available about their tigecycline resistance, virulence, and prevalence in Southwest China. In July 2021,
Jingchen Hao, Bangqin Zhang, Jiamin Deng, Yueshuai Wei, Xue Xiao, Jinbo Liu   +5 more
doaj   +1 more source

Ruptured Emphysematous Prostatic Abscess Caused by K1-ST23 Hypervirulent Klebsiella pneumoniae Presenting as Brain Abscesses: A Case Report and Literature Review

Frontiers in Medicine, 2022
Emphysematous prostatic abscess (EPA) is an extremely rare but potentially fatal urinary tract infection (UTI). Here, we describe a case (a 69-year-old male with prediabetes) of ruptured EPA caused by a hypervirulent Klebsiella pneumoniae (hvKp) K1-ST23 ...
Kensuke Konagaya, Hiroyuki Yamamoto, Tomoyuki Suda, Yusuke Tsuda, Jun Isogai, Hiroyuki Murayama, Yoshichika Arakawa, Hidemitsu Ogino   +7 more
doaj   +1 more source

Role of the ISKpn element in mediating mgrB gene mutations in ST11 hypervirulent colistin-resistant Klebsiella pneumoniae

Frontiers in Microbiology, 2023
BackgroundColistin has emerged as a last-resort therapeutic against antibiotic-resistant bacterial infections, particularly those attributed to carbapenem-resistant Enterobacteriaceae (CRE) like CRKP.
Lanlan Zhu, Ping Li, Ping Li, Ping Li, Guangyi Zhang, Zhiyong He, Xingyu Tao, Xingyu Tao, Yicheng Ji, Wenjing Yang, Xiaofang Zhu, Wanying Luo, Wanying Luo, Wenjian Liao, Chuanhui Chen, Yang Liu, Yang Liu, Wei Zhang, Wei Zhang   +18 more
doaj   +1 more source