Results 11 to 20 of about 19,274 (215)

Antimicrobial Resistance of Hypervirulent Klebsiella pneumoniae: Epidemiology, Hypervirulence-Associated Determinants, and Resistance Mechanisms [PDF]

Frontiers in Cellular and Infection Microbiology, 2017
Klebsiella pneumoniae is one of the most clinically relevant species in immunocompromised individuals responsible for community-acquired and nosocomial infections, including pneumonias, urinary tract infections, bacteremias, and liver abscesses.
Chang-Ro Lee, Chang-Jun Cha, Sang-Hee Lee   +2 more
exaly   +5 more sources

Emergence of Carbapenem-Resistant Hypervirulent ST111 K63 Klebsiella pneumoniae in China [PDF]

Polish Journal of Microbiology
Carbapenem-resistant and hypervirulent Klebsiella pneumoniae have been identified worldwide, posing a significant threat to public health. This study aimed to characterize a novel KPC-harboring plasmid in a carbapenem-resistant and hypervirulent ST111 ...
Zhu Ying, Jia Xinmiao, Jia Peiyao, Liu Xiaoyu, Li Xue, Yu Wei, Yang Qing, Yin Huabing, Hao Qiaoxin, Yang Qiwen   +9 more
doaj   +2 more sources

Emergence of hypervirulent and carbapenem-resistant Klebsiella pneumoniae ST37: genomic and phenotypic characterization of virulence and resistance [PDF]

Frontiers in Microbiology
The emergence and spread of carbapenem-resistant Klebsiella pneumoniae (CRKP) ST37 necessitates urgent reassessment of its pathogenic potential. This study aims to characterize the genomic and phenotypic features of ST37 isolates collected from a ...
Li Shen, Weihua Han, Yu Huang, Shanshan Wang, Haojin Gao, Jinjin Yang, Jiana Fu, Zhixuan Chen, Junhong Shi, Xinru Yuan, Jingyi Yu, Fangyou Yu, Chunyang Wu   +12 more
doaj   +2 more sources

Genomic epidemiology of putative hypervirulent Klebsiella pneumoniae species complex in Dutch patients, January–December 2022 [PDF]

Microbiology Spectrum
Hypervirulent Klebsiella pneumoniae species complex (hvKp) can cause invasive infections with spontaneous abscesses, also in previously healthy individuals.
Karuna E. W. Vendrik, Gijs Teunis, Fardau Anema, Fabian Landman, Angela de Haan, Jeroen Bos, Sandra Witteveen, Annelot F. Schoffelen, Sabine C. de Greeff, Ed J. Kuijper, Antoni P. A. Hendrickx, Daan W. Notermans   +11 more
doaj   +2 more sources

Carriage of hypervirulent and ESBL-producing Klebsiella pneumoniae complex among community-dwelling individuals in Japan [PDF]

Applied and Environmental Microbiology
Despite the increasing number of reports on hypervirulent and extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae infections, data on the distribution of these pathogens in the community are limited.
Akiko Watanabe, Yukio Tawada, Makoto Moriyama, Yohei Doi, Masahiro Suzuki   +4 more
doaj   +2 more sources

Cefiderocol resistance in a clinical ST11-KL64 hypervirulent Klebsiella pneumoniae isolate mediated by a novel CirA truncation and SHV-12 β-lactamase [PDF]

BMC Microbiology
Background Carbapenem-resistant Klebsiella pneumoniae (CRKP) infections have emerged as a major global public health threat. Cefiderocol is a novel siderophore-conjugated cephalosporin with potent activity to treat severe infections caused by CRKP.
Peiyao Zhou, Jiana Fu, Xiaoxia He, Haojin Gao, Chunyang Wu, Fangyou Yu, Ying Zhou   +6 more
doaj   +2 more sources

Emergence and genomic characterization of hypervirulent ST23/K1 Klebsiella pneumoniae: local epidemiology and global context [PDF]

Frontiers in Microbiology
IntroductionHypervirulent Klebsiella pneumoniae (hvKp) of the K1/ST23 lineage is an emerging global threat associated with invasive community-acquired infections.
Matej Bezdicek, Matej Bezdicek, Marketa Jakubickova, Marketa Jakubickova, Viktoria Bitusikova, Viktoria Bitusikova, Ema Holubova, Ema Holubova, Helena Vitkova, Iva Kocmanova, Iva Kocmanova, Ivana Vitkova, Lenka Zdrazilova Dubska, Lenka Zdrazilova Dubska, Martina Lengerova, Martina Lengerova   +15 more
doaj   +2 more sources

Susceptibility of hamsters to clostridium difficile isolates of differing toxinotype [PDF]

, 2013
Clostridium difficile is the most commonly associated cause of antibiotic associated disease (AAD), which caused ~21,000 cases of AAD in 2011 in the U.K. alone.
A Buckley, Anthony M. Buckley, B Elliott, C Rousseau, C Schwan, D Drudy, D Goulding, D Lyras, Denise Candlish, DM Guerrero, F Miyajima, Gillian R. Douce, H Huang, H Kim, H Kim, I Duerden, I Vesteinsdottir, J Andrews, J Kim, J Ng, J Pépin, J Wang, Janice Spencer, JG Bartlett, JM Lanis, June J. Irvine, JW Marsh, LA Petrella, Lindsay M. Maclellan, LJ Deakin, M Arvand, M He, M Merrigan, M Rupnik, MH Wilcox, MH Wilcox, Michel R. Popoff, MM Nerandzic, MSM Brouwer, N Razaq, N Stoesser, P Vohra, R Stabler, R Stabler, S Kamiya, S Kuehne, SA Villano, SP Sambol, SP Sambol, ST Cartman, TS Steiner, V Braun, V Casas, Y Ogura   +53 more
core   +19 more sources

Virulence Factors in Hypervirulent Klebsiella pneumoniae [PDF]

Frontiers in Microbiology, 2021
Hypervirulent Klebsiella pneumoniae (hvKP) has spread globally since first described in the Asian Pacific Rim. It is an invasive variant that differs from the classical K. pneumoniae (cKP), with hypermucoviscosity and hypervirulence, causing community-acquired infections, including pyogenic liver abscess, pneumonia, meningitis, and endophthalmitis.
Jie Zhu, Tao Wang, Liang Chen, Liang Chen, Hong Du   +4 more
openaire   +3 more sources

Hypervirulent Klebsiella pneumoniae

Infection and Drug Resistance, 2023
Hypervirulent Klebsiella pneumoniae (hvKP), especially multidrug-resistant hvKP (MDR-hvKP) infections, are distributed globally, and lead to several outbreaks with high pathogenicity and mortality in immunocompetent individuals. This is usually characterized by a rapidly metastatic spread resulting in multiple pyogenic tissue abscesses.
Junjun Chen, Huan Zhang, Xuelian Liao
openaire   +4 more sources