Antimicrobial Resistance of Hypervirulent Klebsiella pneumoniae: Epidemiology, Hypervirulence-Associated Determinants, and Resistance Mechanisms [PDF]
Klebsiella pneumoniae is one of the most clinically relevant species in immunocompromised individuals responsible for community-acquired and nosocomial infections, including pneumonias, urinary tract infections, bacteremias, and liver abscesses.
Chang-Ro Lee +2 more
exaly +6 more sources
Hypervirulent Klebsiella pneumoniae
Hypervirulent Klebsiella pneumoniae (hvKP), especially multidrug-resistant hvKP (MDR-hvKP) infections, are distributed globally, and lead to several outbreaks with high pathogenicity and mortality in immunocompetent individuals. This is usually characterized by a rapidly metastatic spread resulting in multiple pyogenic tissue abscesses.
Junjun Chen, Huan Zhang, Xuelian Liao
openaire +5 more sources
Emergence of Carbapenem-Resistant Hypervirulent ST111 K63 Klebsiella pneumoniae in China [PDF]
Carbapenem-resistant and hypervirulent Klebsiella pneumoniae have been identified worldwide, posing a significant threat to public health. This study aimed to characterize a novel KPC-harboring plasmid in a carbapenem-resistant and hypervirulent ST111 ...
Zhu Ying +9 more
doaj +2 more sources
The Occurence of Colistin-Resistant Hypervirulent Klebsiellapneumoniae in China [PDF]
Hypervirulent Klebsiella pneumoniae strains are usually susceptible to many antimicrobial agents including colistin. Here we report the isolation and characterization of several colistin-resistant hypervirulent K. pneumoniae clinical strains. K. pneumoniae strains recovered from blood samples were collected at a university hospital in China.
Yang Lu +9 more
core +6 more sources
Metastatic infection of hypervirulent Klebsiella pneumoniae
Hypervirulent Klebsiella pneumoniae(hvKp) has a unique ability to cause organ or life-threatening tissue invasive infection in multiple sites. This case highlights that classical hvKp resulted in multiple abscesses in every body site, especially in the necrotizing fasciitis and osteomyelitis.
Biying Zhang +4 more
openaire +4 more sources
Emergence of hypervirulent and carbapenem-resistant Klebsiella pneumoniae ST37: genomic and phenotypic characterization of virulence and resistance [PDF]
The emergence and spread of carbapenem-resistant Klebsiella pneumoniae (CRKP) ST37 necessitates urgent reassessment of its pathogenic potential. This study aims to characterize the genomic and phenotypic features of ST37 isolates collected from a ...
Li Shen +12 more
doaj +2 more sources
Shuang Song,1,2,* Shulong Zhao,2,* Wei Wang,1 Fei Jiang,2 Jingfang Sun,2 Ping Ma,1,2 Haiquan Kang2 1Medical Technology School, Xuzhou Medical University, Xuzhou, People’s Republic of China; 2Department of Clinical Laboratory, Affiliated Hospital ...
Song S +6 more
doaj +1 more source
Carriage of hypervirulent and ESBL-producing Klebsiella pneumoniae complex among community-dwelling individuals in Japan [PDF]
Despite the increasing number of reports on hypervirulent and extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae infections, data on the distribution of these pathogens in the community are limited.
Akiko Watanabe +4 more
doaj +2 more sources
Cefiderocol resistance in a clinical ST11-KL64 hypervirulent Klebsiella pneumoniae isolate mediated by a novel CirA truncation and SHV-12 β-lactamase [PDF]
Background Carbapenem-resistant Klebsiella pneumoniae (CRKP) infections have emerged as a major global public health threat. Cefiderocol is a novel siderophore-conjugated cephalosporin with potent activity to treat severe infections caused by CRKP.
Peiyao Zhou +6 more
doaj +2 more sources
Suspected community-acquisition of carbapenem-resistant hypervirulent Klebsiella pneumoniae (CRhvKp) in Germany: a case report and implications for infection control [PDF]
Aim: Hypervirulent Klebsiella pneumoniae (hvKp) has emerged as a disease threat due to a higher morbidity and mortality associated with specific virulence genes.
Nora Helke Leder +6 more
doaj +2 more sources

