Results 1 to 10 of about 48,411 (161)
The rapid spread of carbapenem-resistant Enterobacteriaceae [PDF]
Drug Resistance Updates, 2016 Carbapenems, our one-time silver bullet for multidrug resistant bacterial infections, are now threatened by widespread dissemination of carbapenem-resistant Enterobacteriaceae (CRE). Successful expansion of Enterobacteriaceae clonal groups and frequent horizontal gene transfer of carbapenemase expressing plasmids are causing increasing carbapenem ...
Robert F Potter +2 more
exaly +3 more sources
First literature review of carbapenem-resistant Providencia
New Microbes and New Infections, 2018 Providencia species are Gram-negative bacteria that belong to the Enterobacteriaceae family. They have intrinsic resistance to colistin and tigecycline, which makes treatment of the multidrug-resistant strains of Providencia challenging.
M. Abdallah, A. Balshi
doaj +3 more sources
Detection of plasmid-mediated colistin-resistant and carbapenem-resistant genes by multiplex PCR
MethodsX, 2018 A multiplex PCR was described to simultaneously detect mcr-1 and frequently occurring carbapenem-resistant genes including blaKPC, blaNDM, blaIMP, and blaOXA-48-like in a single reaction.
Rujirat Hatrongjit +3 more
doaj +3 more sources
Carbapenem‐resistant Enterobacteriaceae: biology, epidemiology, and management [PDF]
Annals of the New York Academy of Sciences, 2014 Introduced in the 1980s, carbapenem antibiotics have served as the last line of defense against multidrug‐resistant Gram‐negative organisms. Over the last decade, carbapenem‐resistant Enterobacteriaceae (CRE) have emerged as a significant public health threat.
Elizabeth Temkin +2 more
exaly +4 more sources
Carbapenem Resistant Enterobacteriaceae in Africa
Borneo Journal of Pharmacy, 2020 Carbapenems are regarded as unique among the β-lactam antibiotics due to their broad spectrum of activity and ability to resist β-lactamase hydrolysis.
Bashar Haruna Gulumbe, Olumide Ajibola
doaj +3 more sources
Carbapenem-Resistant Enterobacteriaceae [PDF]
Clinics in Laboratory Medicine, 2017 Carbapenem-resistant Enterobacteriaceae (CRE) have emerged as a major threat. Commonly used antibiotics are generally inactive against CRE. Therefore, timely detection of CRE is of paramount importance. Among CRE, those producing carbapenem-hydrolyzing β-lactamase enzymes (carbapenemase-producing Enterobacteriaceae) are particularly of concern because ...
Alina, Iovleva, Yohei, Doi
+9 more sources
Antibiotics, 2023 The emergence of carbapenem-resistant Klebsiella pneumoniae poses a significant threat to public health. In this study, we aimed to investigate the distribution and genetic diversity of plasmids carrying beta-lactamase resistance determinants in a ...
Chien-Hao Tseng +6 more
doaj +1 more source
Carbapenem resistance in Canada [PDF]
Canadian Medical Association Journal, 2009 For more than 2 decades, carbapenems have been considered the pharmacotherapy of last resort for managing multidrug-resistant infections caused by Enterobacteriaceae bacteria (e.g., Escherichia coli and Salmonella ).
Baldwin, Toye +4 more
openaire +2 more sources
Carbapenem Resistance: A Review [PDF]
Medical Sciences, 2017 Carbapenem resistance is a major and an on-going public health problem globally. It occurs mainly among Gram-negative pathogens such as Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii, and may be intrinsic or mediated by transferable carbapenemase-encoding genes.
Francis S. Codjoe, Eric S. Donkor
openaire +3 more sources
BMC Microbiology, 2023 Purpose Carbapenem resistant Klebsiella pneumoniae is associated with nosocomial infections and can cause high mortality, which poses great threat to human health.
Xianzhen Wei +5 more
doaj +1 more source