Results 21 to 30 of about 862,573 (173)

Individualized active surveillance for carbapenem-resistant microorganisms using Xpert Carba-R in intensive care units

Scientific Reports, 2023
Carbapenem antibiotics are widely used in ICU, and the prevalence of carbapenem-resistant microorganisms (CRO) has increased. This study aimed to assess the role of individualized active surveillance using Xpert Carba-R of carbapenem resistance genes on ...
Shuliang Zhou, Sulin Mi, Xin Rao, Qi Zhang, Shiwen Wei, Meng Xiao, Zhiyong Peng, Jing Wang   +7 more
doaj   +1 more source

Carbapenem Resistance in Non-Fermentative Gram-Negative Bacilli Isolated from Intensive Care Unit Patients of a Referral Hospital

Journal of Nepal Health Research Council, 2021
Background: Non-fermentative Gram-negative bacilli or non-fermenters are opportunistic pathogens associated with serious infections in intensive care unit patients.
Santosh Kumar Yadav, Rajshree Bhujel, Shyam Kumar Mishra, Sangita Sharma, Jeevan Bahadur Sherchand   +4 more
doaj   +1 more source

Polyphasic characterization of carbapenem-resistant Klebsiella pneumoniae clinical isolates suggests vertical transmission of the blaKPC-3 gene [PDF]

, 2021
Carbapenem-resistant Klebsiella pneumoniae are a major global threat in healthcare facilities. The propagation of carbapenem resistance determinants can occur through vertical transmission, with genetic elements being transmitted by the host bacterium ...
Lameiras, Catarina,, Brito, Margarida, Manaia, C. M., Pohjanen, Saga, Célia M Manaia, Margarida Brito, Frykholm, Karolin,, Ferreira, Catarina, Nunes, Olga C., Catarina Lameiras, Kumar Bikarolla, Santosh, Saga Pohjanen, Nunes, O. C.,, Nunes, O. C., Brit, Margarida, Kumar Bikarolla, Santosh,, Westerlund, Fredrik, Lameiras, Cataria, Lameiras, Catarina, Karolin Frykholm, Brito, Margarida,, Olga C Nunes, Manaia, C. M.,, Ferreira, Catarina,, Bikkarolla, Santosh Kumar, Frykholm, Karolin, Catarina Ferreira, Pohjanen, Saga,, Bikkarolla, Santosh K., Fredrik Westerlund, Manaia, Célia M., Santosh K Bikkarolla, Westerlund, Fredrik,   +32 more
core   +1 more source

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development

Angewandte Chemie, EarlyView.
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma, Komal Sharma, Anku Sharma, Kamya Rao, Rahul Jain, Brett VanVeller   +5 more
wiley   +2 more sources

Synergistic Activity of Equol and Meropenem against Carbapenem-Resistant Escherichia coli

Antibiotics, 2021
The emergence of carbapenem-resistant Enterobacterales (CRE) seriously limits treatment options for bacterial infections. Combined drugs are an effective strategy to treat these resistant strains.
Hye-Rim Kim, Yong-Bin Eom
doaj   +1 more source

Structure and Biosynthesis of Mangotoxin Produced by the Plant Pathogen Pseudomonas syringae

Angewandte Chemie, EarlyView.
The structure of mangotoxin remained elusive for over two decades. Here, mangotoxin was isolated from the native producer, Pseudomonas syringae pv. syringae, and was determined to be an alkyne‐containing dipeptide. Mangotoxin inhibited the growth of multidrug‐resistant human pathogen Klebsiella pneumoniae.
Alexis H. Murray, Sohan Hazra, Ryan W. Mull, Erinn M. O'Neill, Bo Li   +4 more
wiley   +2 more sources

Distribution of 121 carbapenem-resistant isolates.

, 2023
Distribution of 121 carbapenem-resistant isolates.
Shiwen Sun (1596106), Gejin Lu (13172517), Yang Sun (132532), Lingwei Zhu (624723), Xue Ji (624724), Wenhui Zhang (425538), Xuejun Guo (129079), Hongru Guo (15572656), Mingwei Liu (3369224), Lin Zheng (109927), Jun Liu (42548), Jiayao Guan (12222816), Jie Jing (4805643), Ying Wang (11406), Bowen Jiang (794003), Zixian Wang (10431578)   +15 more
core   +1 more source

Tree diagram for carbapenem-resistant Enterobacterales infections.

, 2022
Tree diagram for carbapenem-resistant Enterobacterales infections.
Nicholas Graves (258283), David Lye (336978), Winnie Lee (328670), Grace S. R. Hoo (14232128), Andrea L. Kwa (8964998), Joanne Yoong (228710), Yiying Cai (328668), Ban Hock Tan (7507319), Yik-Ying Teo (159446)   +8 more
core   +1 more source

Risk factors and outcome associated with coinfection with carbapenem-resistant Klebsiella pneumoniae and carbapenem-resistant Pseudomonas aeruginosa or Acinetobacter baumanii: a descriptive analysis

Frontiers in Cellular and Infection Microbiology, 2023
BackgroundNearly 30% of patients infected with carbapenem-resistant Klebsiella pneumoniae (CRKP) were previously shown to be coinfected with carbapenem-resistant Pseudomonas aeruginosa (CRPA) or Acinetobacter baumannii (CRAB).
Anthony Sophonsri, Corey Kelsom, Corey Kelsom, Mimi Lou, Paul Nieberg, Annie Wong-Beringer, Annie Wong-Beringer   +6 more
doaj   +1 more source

First report of carbapenem-resistant Providencia stuartii in Saudi Arabia

New Microbes and New Infections, 2018
We present the case of 31-year-old man who developed hospital-acquired pneumonia in the intensive care unit. Pathogens were identified to be carbapenem-resistant isolates of Providencia stuartii and Klebsiella pneumoniae.
M. Abdallah, R. Alhababi, N. Alqudah, B. Aldyyat, A. Alharthy   +4 more
doaj   +1 more source