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The prevalence of multidrug-resistant gram-negative bacilli has increased worldwide. Critical care areas of most hospitals use carbapenem antibiotics for the empirical treatment of gram-negative bacterial (GNB) infections.
K.V. Leela +3 more
core +1 more source
Introduction: The increasing prevalence of carbapenem-resistant gram-negative bacilli infection has emerged as a substantial threat to human health.
Lijun Yin +10 more
doaj +1 more source
Background: Acquired carbapenem resistance among non-fermenting Gram-negative bacilli (NFGNB), such as Pseudomonas aeruginosa and Acinetobacter calcoaceticus-Acinetobacter baumannii complex (ACB complex), is a serious problem in nosocomial infections. We
Ying-Chi Huang +3 more
doaj +1 more source
Carbapenem resistance in the food supply chain
Carbapenems are critically important antibiotic agents because they are considered the "last-resort" antibiotics for treating serious infections. However, resistance to carbapenems is increasing throughout the world and has become an urgent problem.
En Huang +3 more
openaire +3 more sources
Background: Bacteraemia due to carbapenem-resistant gram-negative bacteria is challenging. This study examined the burden of carbapenem and colistin resistance in Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii bacteraemia in ...
A. Balkhair +7 more
doaj +1 more source
Carbapenem-Resistant Enterobacteriaceae: Epidemiology and Prevention [PDF]
Over the past 10 years, dissemination of Klebsiella pneumoniae carbapenemase (KPC) has led to an increase in the prevalence of carbapenem-resistant Enterobacteriaceae (CRE) in the United States. Infections caused by CRE have limited treatment options and have been associated with high mortality rates. In the previous year, other carbapenemase subtypes,
Neil, Gupta +3 more
openaire +2 more sources
Carbapenem-Resistant Enterobacteriaceae Infections in Children [PDF]
Carbapenem-resistant Enterobacteriaceae (CRE) are an emerging global public health threat. Infections due to CRE are associated with significant morbidity and mortality. Few therapeutic options are available for treatment of these infections, and optimal antibiotic treatment regimens are unclear.
Kathleen, Chiotos +2 more
openaire +2 more sources
Prevalence of Carbapenem-Resistant Enterobacteriaceae and the Genes Responsible for Carbapenemase Production in a Tertiary Care Hospital in South India [PDF]
Introduction: Carbapenem resistance in Gram-negative bacilli (GNB) is a major concern in the management of resistant infections. The mechanism of carbapenem resistance is most commonly mediated by carbapenemases. The five most common genes (NDM, KPC, VIM,
Archana Mahalingam +5 more
core +1 more source
Aminoglycoside-modifying Enzymes in Carbapenem-resistant Pseudomonas aeruginosa Clinical Isolates
Introduction: Aminoglycosides are the drug of choice for the treatment of Pseudomonas aeruginosa infections. Aminoglycoside resistance in P. aeruginosa often occurred via acquired aminoglycoside-modifying enzymes (AMEs).
Yeliz TANRIVERDİ ÇAYCI +6 more
doaj +1 more source
Carbapenem antibiotics are widely used in ICU, and the prevalence of carbapenem-resistant microorganisms (CRO) has increased. This study aimed to assess the role of individualized active surveillance using Xpert Carba-R of carbapenem resistance genes on ...
Shuliang Zhou +7 more
doaj +1 more source

