Carbapenem Resistant Enterobacteriaceae in Africa
Carbapenems are regarded as unique among the β-lactam antibiotics due to their broad spectrum of activity and ability to resist β-lactamase hydrolysis.
Bashar Haruna Gulumbe, Olumide Ajibola
doaj +3 more sources
Carbapenem-Resistant Enterobacteriaceae [PDF]
Carbapenem-resistant Enterobacteriaceae (CRE) have emerged as a major threat. Commonly used antibiotics are generally inactive against CRE. Therefore, timely detection of CRE is of paramount importance. Among CRE, those producing carbapenem-hydrolyzing β-lactamase enzymes (carbapenemase-producing Enterobacteriaceae) are particularly of concern because ...
Alina, Iovleva, Yohei, Doi
+9 more sources
Carbapenem resistance in Canada [PDF]
For more than 2 decades, carbapenems have been considered the pharmacotherapy of last resort for managing multidrug-resistant infections caused by Enterobacteriaceae bacteria (e.g., Escherichia coli and Salmonella ).
Baldwin, Toye +4 more
openaire +2 more sources
Carbapenem Resistance: A Review [PDF]
Carbapenem resistance is a major and an on-going public health problem globally. It occurs mainly among Gram-negative pathogens such as Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii, and may be intrinsic or mediated by transferable carbapenemase-encoding genes.
Francis S. Codjoe, Eric S. Donkor
openaire +3 more sources
Carbapenem Resistance In Enterobacteriaceae [PDF]
Carbapenem resistance is now a public health concern worldwide. Carbapenem is considered the last resort antimicrobial drug used for treatment of hospital care associated infection and community acquired infection that resistant to all other β-lactam drugs. There are a different mechanisms by which bacteria become resistant to carbapenem drug including
Radwa Farag +3 more
openaire +1 more source
Management of carbapenem-resistant Enterobacteriaceae infections [PDF]
Carbapenem resistance is defined as in vitro non-susceptibility to any carbapenem and/or documented production of a carbapenemase. This feature has rapidly spread worldwide among clinical isolates of Enterobacteriaceae, mostly Klebsiella spp., and is associated with diverse molecular mechanisms. Carbapenem resistance is often associated with resistance
Durante-Mangoni, Emanuele +2 more
openaire +3 more sources
Attributable deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in the EU and the European Economic Area in 2015: a population-level modelling analysis [PDF]
Background: Infections due to antibiotic-resistant bacteria are threatening modern health care. However, estimating their incidence, complications, and attributable mortality is challenging.
Abu Sin, Muna +79 more
core +6 more sources
Background: Acquired carbapenem resistance among non-fermenting Gram-negative bacilli (NFGNB), such as Pseudomonas aeruginosa and Acinetobacter calcoaceticus-Acinetobacter baumannii complex (ACB complex), is a serious problem in nosocomial infections. We
Ying-Chi Huang +3 more
doaj +1 more source
Importance of site of infection and antibiotic selection in the treatment of carbapenem-resistant Pseudomonas aeruginosa sepsis [PDF]
In a retrospective analysis of 215 patients with carbapenem-resistant Pseudomonas aeruginosa sepsis, we observed a significantly higher risk of mortality associated with respiratory tract infection (risk ratio [RR], 1.20; 95 ...
Britt, Nicholas S +6 more
core +2 more sources
The Potential Trajectory of Carbapenem-Resistant Enterobacteriaceae, an Emerging Threat to Health-Care Facilities, and the Impact of the Centers for Disease Control and Prevention Toolkit. [PDF]
Carbapenem-resistant Enterobacteriaceae (CRE), a group of pathogens resistant to most antibiotics and associated with high mortality, are a rising emerging public health threat.
Bartsch, Sarah M +10 more
core +1 more source

