Results 21 to 30 of about 13,389 (213)

Investigations of carbapenem resistant and hypervirulent Klebsiella pneumoniae

Acta Microbiologica et Immunologica Hungarica
AbstractHypervirulent Klebsiella pneumoniae is an emerging pathogen that has gained attention due to its increased ability to cause infections even in healthy individuals. The aim of this study is to investigate virulence factors in K. pneumoniae strains isolated from clinical specimens and their association with carbapenem resistance.
El Mehdi Belouad, Elmostafa Benaissa, Nadia El Mrimar, Yassine Eddair, Adil Maleb, Mostafa Elouennass   +5 more
openaire   +4 more sources

Emergence and Genomic Characterization of a Hypervirulent Klebsiella pneumoniae Isolate From a New Clone in Brazil. [PDF]

Microbiol Immunol
ABSTRACT Hypervirulent Klebsiella pneumoniae (hvKp) has emerged globally as a major public health concern, often associated with severe community‐acquired and healthcare‐associated human infections. Despite alerts from PAHO/WHO on convergent hvKp strains with multidrug resistance in Latin America, comprehensive data from Brazil, the region's largest ...
Camargo CH, Costa ABN, Yamada AY, Miranda DS, Ferraro PSP, Souza AR, Bertani AMJ, Campos KR, Santos MBN, Rissetti RM, Paula CL, Paz PJL, Soares MSD, Salvador C, Pieri GP, Higa JS, Souza DDS, Ribeiro MG, Sacchi CT, Tiba-Casas MR, Madalosso G, Assis DB.   +21 more
europepmc   +2 more sources

Virulence Factors in Hypervirulent Klebsiella pneumoniae [PDF]

Frontiers in Microbiology, 2021
Hypervirulent Klebsiella pneumoniae (hvKP) has spread globally since first described in the Asian Pacific Rim. It is an invasive variant that differs from the classical K. pneumoniae (cKP), with hypermucoviscosity and hypervirulence, causing community-acquired infections, including pyogenic liver abscess, pneumonia, meningitis, and endophthalmitis.
Jie Zhu, Tao Wang, Liang Chen, Liang Chen, Hong Du   +4 more
openaire   +3 more sources

Stool Samples of Acute Diarrhea Inpatients as a Reservoir of ST11 Hypervirulent KPC-2-Producing Klebsiella pneumoniae

mSystems, 2020
The emergence and spread of carbapenem-resistant hypervirulent Klebsiella pneumoniae sequence type 11 (ST11-CR-HvKP) in China are a great concern in the public health community.
Beiwen Zheng, Hao Xu, Tao Lv, Lihua Guo, Yu Xiao, Chen Huang, Shuntian Zhang, Yunbo Chen, Huiming Han, Ping Shen, Yonghong Xiao, Lanjuan Li   +11 more
doaj   +3 more sources

Hypermucoviscosity Regulator RmpD Interacts with Wzc and Controls Capsular Polysaccharide Chain Length

mBio, 2023
Klebsiella pneumoniae is a leading cause of nosocomial infections, including pneumonia, bacteremia, and urinary tract infections. Treatment options are increasingly restricted by the high prevalence of resistance to frontline antibiotics, including ...
Olga G. Ovchinnikova, Logan P. Treat, Tanisha Teelucksingh, Bradley R. Clarke, Taryn A. Miner, Chris Whitfield, Kimberly A. Walker, Virginia L. Miller   +7 more
doaj   +1 more source

A 54‐year‐old healthy patient with meningitis and conjunctivitis

Journal of the American College of Emergency Physicians Open, 2021
We describe a case report of hypermucoviscous Klebsiella pneumoniae (KP) promptly diagnosed by blood and cerebrospinal fluid (CSF) culture with positive string test.
Gilles Troché, Amandine Henry, Florence Sarfati, Charles Hickel, Marlène Amara, Fabrice Bruneel   +5 more
doaj   +1 more source

Hypervirulent Klebsiella pneumoniae [PDF]

Open Forum Infectious Diseases, 2014
Abstract Hypervirulent strains of Klebsiella pneumoniae are associated with abscess formation, commonly hepatic, and metastatic spread, even in healthy patients. We describe a case of this clinical syndrome, genotypic and phenotypic features of the isolate, and briefly review epidemiology, clinical manifestations, and pathogenesis of ...
Patel, Payal K., Karchmer, Adolf, Russo, Thomas A.   +2 more
openaire   +4 more sources

Clinical and Bacterial Characteristics of Klebsiella pneumoniae Affecting 30-Day Mortality in Patients With Bloodstream Infection

Frontiers in Cellular and Infection Microbiology, 2021
BackgroundThere is a paucity of studies using clinical characteristics and whole-genome sequencing together to fully identify the risk factors of patients with Klebsiella pneumoniae (KP) bloodstream infection (BSI).MethodsWe retrospectively analyzed the ...
Xingbing Wu, Qingyi Shi, Shimo Shen, Chen Huang, Hongcheng Wu   +4 more
doaj   +1 more source

Molecular Investigation of Klebsiella pneumoniae from Clinical Companion Animals in Beijing, China, 2017–2019

Pathogens, 2021
This work is aimed to elucidate the prevalence and characteristics of antimicrobial resistance, virulence, and molecular typing in Klebsiella pneumoniae from clinical companion animals in Beijing, China. In total, 105 K.
Zhenbiao Zhang, Lei Lei, Haixia Zhang, Hegen Dai, Yu Song, Lei Li, Yang Wang, Zhaofei Xia   +7 more
doaj   +1 more source

Aerobactin Seems To Be a Promising Marker Compared With Unstable RmpA2 for the Identification of Hypervirulent Carbapenem-Resistant Klebsiella pneumoniae: In Silico and In Vitro Evidence

Frontiers in Cellular and Infection Microbiology, 2021
BackgroundThe incidence of hypervirulent (hv) carbapenem-resistant (CR) Klebsiella pneumoniae (Kp) is increasing globally among various clones and is also responsible for nosocomial infections.
Chaitra Shankar, Soumya Basu, Binesh Lal, Sathiya Shanmugam, Karthick Vasudevan, Purva Mathur, Sudha Ramaiah, Anand Anbarasu, Balaji Veeraraghavan   +8 more
doaj   +1 more source