Frontiers in Microbiology, 2021 Aerobactin is a citrate-hydroxamate siderophore that is critical for the virulence of pathogenic enteric bacteria. However, although the aerobactin-producing iucABCD-iutA operon is distributed widely in the genomes of Yersinia species, none of the ...
Yao Wang, Zhiyan Wei, Zhiqiang Lu
exaly +3 more sources
Aerobactin is a key driver of hypervirulent Klebsiella pneumoniae translocation and virulence. [PDF]
PLoS PathogensHypervirulent Klebsiella pneumoniae (hvKP) is an emerging pathotype capable of causing severe systemic infections. Gastrointestinal (GI) colonization often precedes invasive disease, but the mechanisms driving translocation to extra-intestinal sites are ...
Giovanna E Hernandez +12 more
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Frontiers in Cellular and Infection Microbiology, 2022 This study aimed to analyze the influence of the main aerobactin-encoding gene iucB and the regulator of mucoid phenotype rmpA on the virulence of Klebsiella pneumoniae causing liver abscess.
Zeyu Huang, Yining Zhao, Mengxin Xu
exaly +3 more sources
Emergence of hypervirulent and carbapenem-resistant Klebsiella pneumoniae ST37: genomic and phenotypic characterization of virulence and resistance [PDF]
Frontiers in MicrobiologyThe emergence and spread of carbapenem-resistant Klebsiella pneumoniae (CRKP) ST37 necessitates urgent reassessment of its pathogenic potential. This study aims to characterize the genomic and phenotypic features of ST37 isolates collected from a ...
Li Shen +12 more
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Virulome–resistome convergence in swine-associated multidrug-resistant Escherichia coli from Hungary: virulence marker profiles and zoonotic potential [PDF]
Frontiers in Veterinary ScienceBackgroundSwine production can sustain dense reservoirs of multidrug-resistant (MDR) Escherichia coli in which mobilizable resistance may co-occur with virulence modules relevant to animal health and One Health risk. We profiled the virulome of Hungarian
Ádám Kerek +20 more
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The iucC gene is a major contributor to the virulence of hypervirulent Klebsiella pneumoniae [PDF]
Frontiers in Cellular and Infection MicrobiologyBackgroundHypervirulent Klebsiella pneumoniae (hvKp) is a critical pathogen that causes highly lethal invasive infections with its virulence linked to that of aerobactin, the core siderophore system of hvKp.MethodsHere, 20 porcine-derived K.
Chong Chen +12 more
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Cross-border spread of a mosaic resistance (OXA-48) and virulence (aerobactin) plasmid in Klebsiella pneumoniae: a European Antimicrobial Resistance Genes Surveillance Network investigation, Europe, February 2019 to October 2024 [PDF]
EurosurveillanceAn investigation of the European Antimicrobial Resistance Genes Surveillance Network (EURGen-Net) detected the same mosaic IncHI1B(pNDM-MAR) resistance (OXA-48) and virulence (aerobactin) plasmid in 492 Klebsiella pneumoniae isolates from eight European ...
Anke Kohlenberg
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Antibiotics, 2022 Hypervirulent K. pneumoniae (hvKP) strains possess distinct characteristics such as hypermucoviscosity, unique serotypes, and virulence factors associated with high pathogenicity.
Hisham N. Altayb +7 more
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Pathogens, 2021 The increase in infections with multidrug-resistant and virulent Klebsiella pneumoniae (K. pneumoniae) strains poses a serious threat to public health. However, environmental reservoirs and routes of transmission for Klebsiella spp. that cause infections
Kathleen Klaper +4 more
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Iron-Utilization System in Vibrio vulnificus M2799
Marine Drugs, 2021 Vibrio vulnificus is a Gram-negative pathogenic bacterium that causes serious infections in humans and requires iron for growth. A clinical isolate, V. vulnificus M2799, secretes a catecholate siderophore, vulnibactin, that captures ferric ions from the ...
Katsushiro Miyamoto +10 more
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