Community-acquired invasive liver abscess syndrome caused by a K1 serotype Klebsiella pneumoniae isolate in Brazil: a case report of hypervirulent ST23 [PDF]
Universidade Federal de São Paulo (UNIFESP) Departamento de MedicinaUniversidade Federal de São Paulo (UNIFESP) Departamento de Medicina Divisão de Doenças InfecciosasUNIFESP, Depto. de MedicinaUNIFESP, Depto.
Coutinho, Rosane L +8 more
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Introduction: This retrospective study investigated the clinical etiology of community-acquired bacteremic Klebsiella pneumoniae infections, and characterized laboratory and genetic markers which may be associated with primary liver abscess (PLA ...
Thean Yen Tan +3 more
doaj +1 more source
Comparative proteomics of uropathogenic Escherichia coli during growth in human urine identify UCA-like (UCL) fimbriae as an adherence factor involved in biofilm formation and binding to uroepithelial cells [PDF]
Uropathogenic Escherichia coli (UPEC) are the primary cause of urinary tract infection (UTI) in humans. For the successful colonisation of the human urinary tract, UPEC employ a diverse collection of secreted or surface-exposed virulence factors ...
Allsopp, LP +5 more
core +1 more source
Objectives: Klebsiella pneumoniae is an emerging invasive pathogen in humans and pigs. Resistance against multiple antibiotics in this species is a major health concern and the development of new antibiotics is urgently needed.
Ann-Kathrin Krieger +8 more
doaj +1 more source
Aerobactin Synthesis Proteins as Antivirulence Targets in Hypervirulent Klebsiella pneumoniae [PDF]
Hypervirulent Klebsiella pneumoniae (hvKp) is an underrecognized pathotype of K. pneumoniae since the majority of cases have occurred in East Asia. However, hvKp is a public health threat due to its ability to infect healthy individuals, ongoing dissemination, and acquisition of resistance determinants.
Thomas A. Russo, Andrew M. Gulick
openaire +2 more sources
ColV plasmid-specific aerobactin synthesis by invasive strains of Escherichia coli [PDF]
Certain strains of Escherichia coli associated with bacteremia of humans and domestic animals harbor plasmids that promote efficient iron uptake. The mechanism, which is an important component of the virulence of invasive strains, is independent of the enterobactin system for iron uptake.
P J, Warner +3 more
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Variation in siderophore biosynthetic gene distribution and production across environmental and faecal populations of Escherichia coli. [PDF]
Iron is essential for Escherichia coli growth and survival in the host and the external environment, but its availability is generally low due to the poor solubility of its ferric form in aqueous environments and the presence of iron-withholding proteins
Laura J Searle +4 more
doaj +1 more source
Aerobactin-mediated iron uptake system in intestinal Escherichia coli [PDF]
Escherichia coli strains isolated from children with diarrhea were studied to determine the incidence of the components of the aerobactin system. The production of aerobactin and the presence of the aerobactin receptor were demonstrated using bioassay techniques.
M. Elena-Fernandez-Beros +2 more
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P fimbriae, capsule and aerobactin characterize colonic resident Escherichia coli [PDF]
Resident and transient Escherichia coli strains from the colonic microflora of 13 Swedish schoolgirls were analysed for carriage of genes encoding a range of adhesins (P, type 1 and S fimbriae, Dr haemagglutinin and three varieties of the P fimbrial papG adhesin) and other virulence traits (K1 and K5 capsule, haemolysin and aerobactin) using multiplex ...
F, Nowrouzian, I, Adlerberth, A E, Wold
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Desferrioxamine biosynthesis : diverse hydroxamate assembly by substrate-tolerant acyl transferase DesC [PDF]
Hydroxamate groups play key roles in the biological function of diverse natural products. Important examples include trichostatin A, which inhibits histone deacetylases via coordination of the active site zinc(II) ion with a hydroxamate group, and the ...
Alkhalaf, Lona M. +5 more
core +1 more source

