Results 1 to 10 of about 128,077 (204)

Antimicrobial Resistance of Hypervirulent Klebsiella pneumoniae: Epidemiology, Hypervirulence-Associated Determinants, and Resistance Mechanisms

Frontiers in Cellular and Infection Microbiology, 2017
Klebsiella pneumoniae is one of the most clinically relevant species in immunocompromised individuals responsible for community-acquired and nosocomial infections, including pneumonias, urinary tract infections, bacteremias, and liver abscesses.
Chang-Jun Cha, Sang Hee Lee, Chang-Ro Lee   +2 more
exaly   +4 more sources

Epidemiological Characteristics and Molecular Evolution Mechanisms of Carbapenem-Resistant Hypervirulent Klebsiella pneumoniae

Frontiers in Microbiology, 2022
Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP), a type of Klebsiella pneumoniae (KP) that exhibits hypervirulence and carbapenem resistance phenotypes, can cause severe infections, both hospital- and community-acquired infections.
Wenqi Zheng, Zhi-De Hu, Jian-Xun Wen
exaly   +3 more sources

Emergence of colistin-heteroresistant and carbapenem-resistant hypervirulent Klebsiella pneumoniae

Journal of Global Antimicrobial Resistance, 2023
: Objectives: To investigate the clinical emergence of colistin-heteroresistant, hypervirulent, and multidrug-resistant Klebsiella pneumoniae, and characterize the underlying molecular mechanisms.
Tao Wang, Xiaojun Wang, Suming Chen, Jie Zhu, Zhichen Zhu, Fen Qu, Liang Chen, Hong Du   +7 more
doaj   +2 more sources

Outer Membrane Vesicles-Transmitted Virulence Genes Mediate the Emergence of New Antimicrobial-Resistant Hypervirulent Klebsiella pneumoniae

Emerging Microbes and Infections, 2022
Hypervirulent Klebsiella pneumoniae (hvKp) is a notorious clinical pathogen that is more likely to cause severe primary and metastatic abscesses. The dissemination of antimicrobial-resistant hvKp isolates has been reported worldwide, posing a great ...
Qian Wang, Biao Yang, Ruyi Zhang
exaly   +3 more sources

A case of neck abscess caused by rare hypervirulent Klebsiella pneumoniae, capsular type K20 and sequence type 420

Annals of Clinical Microbiology and Antimicrobials, 2021
Background This case report describes a neck abscess caused by a strain of Hypervirulent Klebsiella pneumoniae in a middle aged man with diabetes without a history of travel to East and South East Asia.
John Alexander McHardy, Vathshalan Selvaganeshapillai, Priya Khanna, Ashley Michael Whittington, Jane Turton, Guduru Gopal Rao   +5 more
doaj   +1 more source

Fatal disseminated pyogenic infection due to hypermucoviscous hypervirulent Klebsiella pneumoniae: A case report and literature review

Clinical Case Reports, 2021
Hypervirulent Klebsiella pneumonia is becoming recognized globally and has been associated with serious sequelae including death. However, ethnicity and metastatic infections are characteristics for hypermucoviscous hypervirulent Klebsiella pneumoniae ...
Emad M. Salawati
doaj   +1 more source

COVID-19 and Fatal Sepsis Caused by Hypervirulent Klebsiella pneumoniae, Japan, 2020

Emerging Infectious Diseases, 2021
A patient in Japan with coronavirus disease and hypervirulent Klebsiella pneumoniae K2 sequence type 86 infection died of respiratory failure. Bacterial and fungal co-infections caused by region-endemic pathogens, including hypervirulent K. pneumoniae in
Tomohiro Hosoda, Sohei Harada, Koh Okamoto, Sumire Ishino, Makoto Kaneko, Masahiro Suzuki, Ryota Ito, Miyuki Mizoguchi   +7 more
doaj   +1 more source

Pediatric brain abscess with fatal outcome caused by hypervirulent Klebsiella pneumoniae, serotype K2-ST65

Journal of Infection and Public Health, 2023
Hypervirulent Klebsiella pneumoniae (hvKp) is an emerging pathotype in addition to classical Klebsiella pneumoniae, with its ability to cause life-threatening, community-acquired metastatic infections even in healthy individuals.
Emily Tan Sheau En, Nabilah Ismail, Nur Syafiqah Mohamad Nasir, Yasmin Khairani Muhammad Ismadi, Nik Mohd Noor Nik Zuraina, Siti Asma’ Hassan   +5 more
doaj   +1 more source

Co-occurrence of three different plasmids in an extensively drug-resistant hypervirulent Klebsiella pneumoniae isolate causing urinary tract infection

Journal of Global Antimicrobial Resistance, 2020
Objectives: A single carbapenem-resistant, hypervirulent Klebsiella pneumoniae strain has attracted major public concern. The aim of the present study was to better understand the antimicrobial resistance and genetic characteristics of Klebsiella ...
Xiaokui Zhu, Chuanyu Sun, Hongyin Chen, Xiaodie Zhan, Chenxin Liu, Xin Liu, Changwu Yue, Hong Song, Hongling Lu, Xu Jia   +9 more
doaj   +1 more source

Urine-mediated suppression of Klebsiella pneumoniae mucoidy is counteracted by spontaneous Wzc variants altering capsule chain length

mSphere, 2023
Klebsiella pneumoniae is a hospital-associated pathogen primarily causing urinary tract infections (UTIs), pneumonia, and septicemia. Two challenging lineages include the hypervirulent strains, causing invasive community-acquired infections, and the ...
Saroj Khadka, Brooke E. Ring, Ryan S. Walker, Lindsey R. Krzeminski, Drew A. Pariseau, Matthew Hathaway, Harry L. T. Mobley, Laura A. Mike   +7 more
doaj   +1 more source