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Hypervirulent Klebsiella pneumoniae Infections: A Systematic Review of Clinical, Microbiological, and Outcome Data From Reported Cases. [PDF]

Microbiologyopen
Distribution of organ involvement in reported hypervirulent Klebsiella pneumoniae cases. Studies restricted to isolated liver abscess cases were excluded. Percentages represent the proportion of cases with documented involvement of each anatomical site among cases with available data.
Sakru N, Cetinkaya E, Aldi FI, Inan M, Eryildiz C.   +4 more
europepmc   +2 more sources

Epidemiological characteristics and molecular evolution mechanisms of carbapenem-resistant hypervirulent Klebsiella pneumoniae

Frontiers in Microbiology, 2022
Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP), a type of Klebsiella pneumoniae (KP) that exhibits hypervirulence and carbapenem resistance phenotypes, can cause severe infections, both hospital- and community-acquired infections.
Zhi-De Hu, Wen-Qi Zheng, Hu Zhi-De
exaly   +3 more sources

Emergence and Genomic Characterization of a Hypervirulent Klebsiella pneumoniae Isolate From a New Clone in Brazil. [PDF]

Microbiol Immunol
ABSTRACT Hypervirulent Klebsiella pneumoniae (hvKp) has emerged globally as a major public health concern, often associated with severe community‐acquired and healthcare‐associated human infections. Despite alerts from PAHO/WHO on convergent hvKp strains with multidrug resistance in Latin America, comprehensive data from Brazil, the region's largest ...
Camargo CH, Costa ABN, Yamada AY, Miranda DS, Ferraro PSP, Souza AR, Bertani AMJ, Campos KR, Santos MBN, Rissetti RM, Paula CL, Paz PJL, Soares MSD, Salvador C, Pieri GP, Higa JS, Souza DDS, Ribeiro MG, Sacchi CT, Tiba-Casas MR, Madalosso G, Assis DB.   +21 more
europepmc   +2 more sources

Outer membrane vesicles-transmitted virulence genes mediate the emergence of new antimicrobial-resistant hypervirulent Klebsiella pneumoniae

Emerging Microbes and Infections, 2022
Hypervirulent Klebsiella pneumoniae (hvKp) is a notorious clinical pathogen that is more likely to cause severe primary and metastatic abscesses. The dissemination of antimicrobial-resistant hvKp isolates has been reported worldwide, posing a great ...
Ruyi Zhang, Biao Yang, Lei Zheng
exaly   +3 more sources

Antimicrobial Resistance of Hypervirulent Klebsiella pneumoniae: Epidemiology, Hypervirulence-Associated Determinants, and Resistance Mechanisms

Frontiers in Cellular and Infection Microbiology, 2017
Klebsiella pneumoniae is one of the most clinically relevant species in immunocompromised individuals responsible for community-acquired and nosocomial infections, including pneumonias, urinary tract infections, bacteremias, and liver abscesses.
Chang-Ro Lee, Jeong Ho Jeon, Young Bae Kim   +2 more
exaly   +3 more sources

A case of neck abscess caused by rare hypervirulent Klebsiella pneumoniae, capsular type K20 and sequence type 420

Annals of Clinical Microbiology and Antimicrobials, 2021
Background This case report describes a neck abscess caused by a strain of Hypervirulent Klebsiella pneumoniae in a middle aged man with diabetes without a history of travel to East and South East Asia.
John Alexander McHardy, Vathshalan Selvaganeshapillai, Priya Khanna, Ashley Michael Whittington, Jane Turton, Guduru Gopal Rao   +5 more
doaj   +1 more source

COVID-19 and Fatal Sepsis Caused by Hypervirulent Klebsiella pneumoniae, Japan, 2020

Emerging Infectious Diseases, 2021
A patient in Japan with coronavirus disease and hypervirulent Klebsiella pneumoniae K2 sequence type 86 infection died of respiratory failure. Bacterial and fungal co-infections caused by region-endemic pathogens, including hypervirulent K. pneumoniae in
Tomohiro Hosoda, Sohei Harada, Koh Okamoto, Sumire Ishino, Makoto Kaneko, Masahiro Suzuki, Ryota Ito, Miyuki Mizoguchi   +7 more
doaj   +1 more source

Fatal disseminated pyogenic infection due to hypermucoviscous hypervirulent Klebsiella pneumoniae: A case report and literature review

Clinical Case Reports, 2021
Hypervirulent Klebsiella pneumonia is becoming recognized globally and has been associated with serious sequelae including death. However, ethnicity and metastatic infections are characteristics for hypermucoviscous hypervirulent Klebsiella pneumoniae ...
Emad M. Salawati
doaj   +1 more source

Pediatric brain abscess with fatal outcome caused by hypervirulent Klebsiella pneumoniae, serotype K2-ST65

Journal of Infection and Public Health, 2023
Hypervirulent Klebsiella pneumoniae (hvKp) is an emerging pathotype in addition to classical Klebsiella pneumoniae, with its ability to cause life-threatening, community-acquired metastatic infections even in healthy individuals.
Emily Tan Sheau En, Nabilah Ismail, Nur Syafiqah Mohamad Nasir, Yasmin Khairani Muhammad Ismadi, Nik Mohd Noor Nik Zuraina, Siti Asma’ Hassan   +5 more
doaj   +1 more source

Emergence of colistin-heteroresistant and carbapenem-resistant hypervirulent Klebsiella pneumoniae

Journal of Global Antimicrobial Resistance, 2023
: Objectives: To investigate the clinical emergence of colistin-heteroresistant, hypervirulent, and multidrug-resistant Klebsiella pneumoniae, and characterize the underlying molecular mechanisms.
Tao Wang, Xiaojun Wang, Suming Chen, Jie Zhu, Zhichen Zhu, Fen Qu, Liang Chen, Hong Du   +7 more
doaj   +1 more source