Hypervirulent Klebsiella pneumoniae
Junjun Chen,1,2 Huan Zhang,1,3 Xuelian Liao1,2 1Department of Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 2Department of Critical Care Medicine, West China Tianfu Hospital of Sichuan University ...
Chen J, Zhang H, Liao X
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Peculiar purulence: Hypervirulent Klebsiella pneumoniae causing pyomyositis [PDF]
This report describes the first confirmed case of isolated pyomyositis caused by a hypervirulent strain of Klebsiella pneumoniae. Pyomyositis is almost universally caused by gram-positive organisms and while the recent emergence of invasive disease due ...
Okechukwu Mgbemena +5 more
doaj +4 more sources
Phenotypic screening of hypervirulent Klebsiella pneumoniae using tellurite resistance and carbohydrate fermentation testing [PDF]
Phenotypic identification of hypervirulent Klebsiella pneumoniae in routine laboratories remains challenging. We evaluated tellurite resistance and selected carbohydrate fermentation tests as phenotypic tools for screening hypervirulent strains and ...
Koji Ohyama +8 more
doaj +3 more sources
Carbapenem Resistance Conferred by OXA-48 in K2-ST86 Hypervirulent Klebsiella pneumoniae, France
We recovered 2 carbapenem-resistant K2-ST86 hypermucoviscous Klebsiella pneumoniae isolates from patients in France. The isolates had genetic attributes of hypervirulent K. pneumoniae but differed in ability to cause mouse lethality.
Racha Beyrouthy +4 more
doaj +2 more sources
Single‐Cell Atlas Reveals Neutrophil Heterogeneity in Hypervirulent Klebsiella pneumoniae Infection‐Induced Sepsis [PDF]
The roles of distinct lung neutrophil compartments involved in hvKp infection remain poorly understood. Here, utilising single‐cell RNA sequencing, we identified four neutrophil subsets in the lungs of hvKp‐infected mice: N1, N2, N3a, and N3b, which were organised along a maturation trajectory.
Xiang Fang +7 more
wiley +2 more sources
Hypervirulent Klebsiella pneumoniae in Cryptogenic Liver Abscesses, Paris, France [PDF]
Liver abscesses containing hypervirulent Klebsiella pneumoniae have emerged during the past 2 decades, originally in Southeast Asia and then worldwide. We hypothesized that hypervirulent K. pneumoniae might also be emerging in France. In a retrospective,
Benjamin Rossi +11 more
doaj +3 more sources
Metastatic infection of hypervirulent Klebsiella pneumoniae
Hypervirulent Klebsiella pneumoniae(hvKp) has a unique ability to cause organ or life-threatening tissue invasive infection in multiple sites. This case highlights that classical hvKp resulted in multiple abscesses in every body site, especially in the ...
Yunfei Tang +4 more
core +4 more sources
Virulence factors in carbapenem-resistant hypervirulent Klebsiella pneumoniae [PDF]
Hypervirulence and carbapenem-resistant have emerged as two distinct evolutionary pathotypes of Klebsiella pneumoniae, with both reaching their epidemic success and posing a great threat to public health.
Cátia Caneiras +10 more
core +5 more sources
A Case Report of Endogenous Endophthalmitis Associated With a Pyogenic Liver Abscess Caused by Hypervirulent Klebsiella pneumoniae [PDF]
ABSTRACT Objective Pyogenic liver abscess (PLA) caused by hypervirulent Klebsiella pneumoniae (hvKp) may be complicated by endogenous endophthalmitis (EE) and pneumonia. We herein report a case of a Chinese male patient with PLA and bilateral EE caused by hvKp to highlight the severe clinical outcomes of this condition.
Changjiang Liu +8 more
wiley +2 more sources
Molecular Insights Into Hypervirulent Klebsiella pneumoniae: Identification and Correlation of Virulence Determinant [PDF]
Genotypic characterization of 82 clinical K. pneumoniae isolates identified 34 hypervirulent strains. The peg‐344 most strongly associated with hypervirulence (p = 0.0001) but with only 58.8% sensitivity and no signal in over 40% of hvKP isolates, it's a confirmatory marker, not a standalone diagnostic. ABSTRACT Klebsiella pneumoniae is an increasingly
Fathy M. Elkady +8 more
wiley +2 more sources

