Results 31 to 40 of about 4,353 (174)

Clinical Epidemiology, Risk Factors, and Control Strategies of Klebsiella pneumoniae Infection

Frontiers in Microbiology, 2021
Klebsiella species cause infections at multiple sites, including lung, urinary tract, bloodstream, wound or surgical site, and brain. These infections are more likely to occur in people with preexisting health conditions.
De Chang, De Chang, Lokesh Sharma, Charles S. Dela Cruz, Dong Zhang, Dong Zhang   +5 more
doaj   +1 more source

A global perspective on the convergence of hypervirulence and carbapenem resistance in Klebsiella pneumoniae

Journal of Global Antimicrobial Resistance, 2021
Hypervirulence and carbapenem resistance have emerged as two distinct evolutionary directions for Klebsiella pneumoniae, which pose a great threat in clinical settings.
Peng Lan, Yan Jiang, Jiancang Zhou, Yunsong Yu   +3 more
doaj   +1 more source

A Step Forward in Hypervirulent Klebsiella pneumoniae Diagnostics. [PDF]

Emerg Infect Dis
Hypervirulent Klebsiella pneumoniae (hvKp) can cause life-threatening infections in healthy community members. HvKp infections often involve multiple sites, some of which are unusual for classical K. pneumoniae (cKp) infections, such as the central nervous system, eyes, and fascia.
Russo TA, Lebreton F, McGann PT.
europepmc   +4 more sources

Community-acquired liver abscess caused by capsular genotype K2-ST375 hypervirulent Klebsiella pneumoniae isolates

IDCases, 2019
Hypervirulent Klebsiella pneumoniae has been associated with community-acquired liver abscesses in relatively healthy subjects since the 1990s, occasionally accompanied by disseminated disease. While isolates of capsular genotype K1 belonging to sequence
Kosuke Hoashi, Sohei Harada, Yoshikazu Ishii, Kotaro Aoki, Shin Ishikawa, Yusuke Oshiro, Takashi Shinzato   +6 more
doaj   +1 more source

Transmission of Nonconjugative Virulence or Resistance Plasmids Mediated by a Self-Transferable IncN3 Plasmid from Carbapenem-Resistant Klebsiella pneumoniae

Microbiology Spectrum, 2022
Klebsiella pneumoniae poses a critical challenge to clinical and public health. Along with conjugative plasmids, nonconjugative resistance or virulence plasmids associated with carbapenem-resistant K. pneumoniae (CRKP), hypervirulent K. pneumoniae (hvKP),
Xiaoli Wang, Bin Tang, Guitian Liu, Meng Wang, Jingyong Sun, Ruoming Tan, Tingting Pan, Jieming Qu, Jialin Liu, Hong-Yu Ou, Hongping Qu   +10 more
doaj   +1 more source

Hypervirulent (hypermucoviscous)Klebsiella pneumoniae [PDF]

Virulence, 2013
A new hypervirulent (hypermucoviscous) variant of Klebsiella pneumoniae has emerged. First described in the Asian Pacific Rim, it now increasingly recognized in Western countries. Defining clinical features are the ability to cause serious, life-threatening community-acquired infection in younger healthy hosts, including liver abscess, pneumonia ...
Shon, Alyssa S., Bajwa, Rajinder P.S., Russo, Thomas A.   +2 more
openaire   +2 more sources

Pyogenic spondylitis caused by Klebsiella pneumoniae: Should the possibility of hypervirulent Klebsiella pneumoniae be considered?

BMC Infectious Diseases, 2022
Abstract Background Klebsiella pneumoniae is rare but the second most common causative agent among gram-negative bacteria that cause pyogenic spondylitis. However, there are no available studies on the serotype, virulence factors, and clinical characteristics associated with K. pneumoniae-caused pyogenic spondylitis.
Joo-Hee Hwang, Seung Yeob Lee, Jaehyeon Lee, Jeong-Hwan Hwang   +3 more
openaire   +3 more sources

Molecular Epidemiology of Hypervirulent Carbapenemase-Producing Klebsiella pneumoniae [PDF]

Frontiers in Cellular and Infection Microbiology, 2021
ObjectiveTo investigate the overall distributions of key virulence genes in Klebsiella pneumoniae, especially the hypervirulent blaKPC-positive K. pneumoniae (Hv-blaKPC(+)-KP).MethodsA total of 521 complete genomes of K. pneumoniae from GenBank were collected and analyzed.
Dakang Hu, Yuming Li, Ping Ren, Dongxing Tian, Wenjie Chen, Pan Fu, Pan Fu, Weiwen Wang, Xiaobin Li, Xiaofei Jiang   +9 more
openaire   +3 more sources

Arginine regulates the mucoid phenotype of hypervirulent Klebsiella pneumoniae. [PDF]

Nat Commun
Hypervirulent Klebsiella pneumoniae causes severe community-acquired infections, with its mucoid phenotype resulting from altered capsular polysaccharide chain length. While both environmental and genetic factors influence mucoidy, the cues regulating it remain unclear.
Ryan BE, Holmes CL, Stark DJ, Shepard GE, Mills EG, Khadka S, Van Tyne D, Bachman MA, Mike LA.   +8 more
europepmc   +3 more sources

Eco‐Geography Reverses Dominant AMR Reservoirs in Klebsiella pneumoniae: Integron‐Rich Mobilomes and Cross‐Niche Connectivity

Advanced Science, EarlyView.
Dominant antimicrobial resistance reservoirs in Klebsiella pneumoniae vary across eco‐geographic settings rather than following a universal pattern. Integrated One Health and global genomic analyses show that lineage structure, integron load, and cross‐niche connectivity shape whether AMR burden accumulates primarily in human or nonhuman compartments ...
Hui Lin, Biao Tang, Hao Xu, Jiajie Qian, Feifan Shi, Junhui Zhao, Xiaorui Mao, Xiaohe Hu, Ruishan Liu, Wenhong Liu, Xiawei Jiang, Beiwen Zheng, Guoping Zhao   +12 more
wiley   +1 more source