Results 51 to 60 of about 115,878 (208)

A Step Forward in Hypervirulent Klebsiella pneumoniae Diagnostics. [PDF]

Emerg Infect Dis
Hypervirulent Klebsiella pneumoniae (hvKp) can cause life-threatening infections in healthy community members. HvKp infections often involve multiple sites, some of which are unusual for classical K. pneumoniae (cKp) infections, such as the central nervous system, eyes, and fascia.
Russo TA, Lebreton F, McGann PT.
europepmc   +4 more sources

Interpretation of Key Updates in the 36th Edition of Clinical and Laboratory Standards Institute M100 Standard

iLABMED, EarlyView.
ABSTRACT The Clinical and Laboratory Standards Institute M100 document serves as a cornerstone standard for clinical microbiology laboratories in China. Maintaining the scientific rigor of its predecessors, the 36th edition incorporates updated epidemiological cutoff values, pharmacokinetic/pharmacodynamic data, and clinical efficacy evidence to revise
Kanghong Xu, Qi Wang, Hui Wang
wiley   +1 more source

Occurrence and Genomic Characteristics of Hypervirulent Klebsiella pneumoniae in a Tertiary Care Hospital, Eastern India

, 2023
Bhuvan Yadav, Srujana Mohanty, Bijayini Behera Department of Microbiology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, 751019, IndiaCorrespondence: Srujana Mohanty, Department of Microbiology, All India Institute of Medical Sciences ...
Mohanty S, Yadav B, Behera B
core  

Molecular Epidemiology of Antimicrobial Resistance, Virulence and Capsular Serotypes of Carbapenemase-Carrying Klebsiella pneumoniae in China

Antibiotics, 2022
This study analyzed genomic data of 4643 strains of carbapenemase-carrying Klebsiella pneumoniae (KPN) in China by using the Kleborate software package.
Lina Zhao, Xinxin Xia, Ting Yuan, Junying Zhu, Zhen Shen, Min Li   +5 more
doaj   +1 more source

Monocyte inflammation and adaptive immune dysfunction in severe Klebsiella pneumoniae pneumonia

iMeta, EarlyView.
Severe Klebsiella pneumoniae pneumonia combines intense inflammation with failure to control infection, yet the cellular basis is unclear. Using a severity‐focused single‐cell atlas of 708,894 peripheral blood mononuclear cells from 100 individuals, complemented by plasma protein measurements and flow cytometry, we show that disease severity redirects ...
Hongquan Chen, Xiaoling Wang, Xiang Liu, Kui Dong, Yanying Feng, Min Yuan, Shiyi Wang, Fangfang Fan, Yong Tian, Zhiming Kang, Xiushuai Du, Chaolu Hasi, Hong Lu, Wei Guan, Xu Chen, Mengyu Cheng, Wei Wei, Nan Guo, Zhiguo Liu, Xiaotong Qiu, Yiwei Shi, Kun Xiao, Yi Wang, Zhenjun Li   +23 more
wiley   +1 more source

Extensively drug-resistant Klebsiella pneumoniae pneumonia: A case report

Journal of Acute Disease, 2020
Rationale: Extensively drug resistant Klebsiella pneumoniae is defined as resistant to least one antimicrobial agent in all but two or lesser antimicrobial categories.
Saurabh Karmakar, Somnath Bhattacharya, Shilpi Karmakar, Deependra Kumar Rai   +3 more
doaj   +1 more source

Different gut microbiome dysbioses impact the evolutionary fate of hypervirulent Klebsiella pneumoniae

iMeta, EarlyView.
Transient exposure to ampicillin results in restructuring of microbiota to favor oxygen‐tolerant bacteria, whereas osmotic laxative perturbation preserves Bacteriodota. Ampicillin‐ but not laxative‐exposed environment favors establishment of rmpA phase variants that lost hypermucoviscosity but short‐chain fatty acids present in the laxative‐exposed gut
Carey Lim, Jialing Zheng, Guoxiang Cheam, Melvin Yong, Hanrong Chen, Andrew Ting, Yahua Chen, Qingqing Wang, Niranjan Nagarajan, Yunn‐Hwen Gan   +9 more
wiley   +1 more source

Genotypic And Phenotypic Surveillance Of Multidrug Resistance Of Hypermucoid K. Pneumoniae Among Clinical Isolates In AL Najaf City /Iraq

Magazin of Al-Kufa University for Biology
Hypervirulent Klebsiella pneumoniae strains  are the major cause of liver abscesses ,diabetes foot ulcers  and other  infections throughout Iraq, and these strains are usually antibiotics susceptible. Recently, hypervirulent K.
Ali Hussain Hmood, Mahdi H.M. Alammar
doaj   +1 more source

Single‐Cell Atlas Reveals Neutrophil Heterogeneity in Hypervirulent Klebsiella pneumoniae Infection‐Induced Sepsis

Immunology, EarlyView.
The roles of distinct lung neutrophil compartments involved in hvKp infection remain poorly understood. Here, utilising single‐cell RNA sequencing, we identified four neutrophil subsets in the lungs of hvKp‐infected mice: N1, N2, N3a, and N3b, which were organised along a maturation trajectory.
Xiang Fang, Weizhao Li, Xinyu Zhang, Sohana Akter Mina, Qianling Jiang, Gaochen Zhu, Sheng Chen, Guan Yang   +7 more
wiley   +1 more source

Detection of Biofilm Formation in Classical and Hypervirulent Klebsiella pneumoniae [PDF]

, 2023
Klebsiella pneumoniae has considered as a relevant healthcare-associated pathogen, its risk of infections is increasing in the presence of medical devices. K. pneumoniae is known for its ability to form biofilm on biotic and abiotic surfaces.
Nadal Abdulamer Al-Saryi, Iman Mohammad Mahmood Alansary   +1 more
core   +1 more source