Results 61 to 70 of about 128,077 (204)

Hypervirulent Klebsiella pneumoniae – clinical and molecular perspectives [PDF]

Journal of Internal Medicine, 2019
Abstract Hypervirulent Klebsiella pneumoniae (hvKp) has emerged as a concerning global pathogen. hvKp is more virulent than classical K. pneumoniae (cKp) and capable of causing community‐acquired infections, often in healthy ...
J. E. Choby, J. Howard‐Anderson, D. S. Weiss   +2 more
openaire   +2 more sources

Molecular Epidemiology of Antimicrobial Resistance, Virulence and Capsular Serotypes of Carbapenemase-Carrying Klebsiella pneumoniae in China

Antibiotics, 2022
This study analyzed genomic data of 4643 strains of carbapenemase-carrying Klebsiella pneumoniae (KPN) in China by using the Kleborate software package.
Lina Zhao, Xinxin Xia, Ting Yuan, Junying Zhu, Zhen Shen, Min Li   +5 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, Volume 600, Issue 19, Page 2947-2960, October 2026.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Genotypic And Phenotypic Surveillance Of Multidrug Resistance Of Hypermucoid K. Pneumoniae Among Clinical Isolates In AL Najaf City /Iraq

Magazin of Al-Kufa University for Biology
Hypervirulent Klebsiella pneumoniae strains  are the major cause of liver abscesses ,diabetes foot ulcers  and other  infections throughout Iraq, and these strains are usually antibiotics susceptible. Recently, hypervirulent K.
Ali Hussain Hmood, Mahdi H.M. Alammar
doaj   +1 more source

Monocyte inflammation and adaptive immune dysfunction in severe Klebsiella pneumoniae pneumonia

iMeta, Volume 5, Issue 5, October 2026.
Severe Klebsiella pneumoniae pneumonia combines intense inflammation with failure to control infection, yet the cellular basis is unclear. Using a severity‐focused single‐cell atlas of 708,894 peripheral blood mononuclear cells from 100 individuals, complemented by plasma protein measurements and flow cytometry, we show that disease severity redirects ...
Hongquan Chen, Xiaoling Wang, Xiang Liu, Kui Dong, Yanying Feng, Min Yuan, Shiyi Wang, Fangfang Fan, Yong Tian, Zhiming Kang, Xiushuai Du, Chaolu Hasi, Hong Lu, Wei Guan, Xu Chen, Mengyu Cheng, Wei Wei, Nan Guo, Zhiguo Liu, Xiaotong Qiu, Yiwei Shi, Kun Xiao, Yi Wang, Zhenjun Li   +23 more
wiley   +1 more source

Occurrence and Genomic Characteristics of Hypervirulent Klebsiella pneumoniae in a Tertiary Care Hospital, Eastern India

, 2023
Bhuvan Yadav, Srujana Mohanty, Bijayini Behera Department of Microbiology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, 751019, IndiaCorrespondence: Srujana Mohanty, Department of Microbiology, All India Institute of Medical Sciences ...
Mohanty S, Yadav B, Behera B
core  

Hypervirulent Klebsiella pneumoniae infection in a woman with a CDH1 gene mutation

, 2021
The CDH1 gene, which encodes E-cadherin, may be associated with cancer when mutated, but the significance of mutations in the context of infection is unknown.
Roberto Viau Colindres, Adam T. Chin, Alexander J. Kaye, Michelle C. Liang   +3 more
core   +1 more source

Extensively drug-resistant Klebsiella pneumoniae pneumonia: A case report

Journal of Acute Disease, 2020
Rationale: Extensively drug resistant Klebsiella pneumoniae is defined as resistant to least one antimicrobial agent in all but two or lesser antimicrobial categories.
Saurabh Karmakar, Somnath Bhattacharya, Shilpi Karmakar, Deependra Kumar Rai   +3 more
doaj   +1 more source

Molecular Diagnostics for WHO Priority Bacterial Pathogens: A Bibliometric Mapping of Diagnostic Platforms, Resistance Markers, and Antimicrobial Resistance Research Trends

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
This bibliometric mapping of 1746 publications (2000–2025) charts molecular diagnostics for WHO priority bacterial pathogens across platforms, targets, and resistance markers. Conventional PCR/NAAT and whole‐genome sequencing emerge as complementary core platforms, and the field evolves from targeted pathogen detection into an AMR‐centered ...
Selahattin Ünlü
wiley   +1 more source

Annotated genome sequences of Klebsiella pneumoniae strains 35 and 36 from China

, 2023
Annotated complete genome sequences of hypervirulent Klebsiella pneumoniae strains 35 and 36. Both strains carried a KpVP-3 virulence plasmid.
Shirley (6876041)
core   +1 more source