Results 81 to 90 of about 115,878 (208)

Pre‐Clinical Development of Two DNA Vaccines Encoding MrkA of Klebsiella pneumoniae: Effect of Plasmid Backbone on Immunogenicity and Protective Efficacy Against Sepsis

Microbial Biotechnology, Volume 19, Issue 8, August 2026.
Pre‐clinical development of two DNA vaccines encoding the MrkA fimbrial subunit of Klebsiella pneumoniae using different plasmid backbones: pVAX1 (commercial) and PLASMIVAX (with additional CpG motifs). Both DNA vaccine candidates expressed the antigen in eukaryotic cells but differed in their immunogenicity and protective efficacy against sepsis in ...
Marta Vicente‐Pazos, Estéfani García‐Ríos, Laura Quílez‐Agraz, Gal·la Ustrell‐Sallent, Pilar Pérez‐Romero, Mireia López‐Siles, Michael J. McConnell   +6 more
wiley   +1 more source

Determinação fenotípica e genotípica de beta-lactamases de espetro estendido em Escherichia coli, Klebsiella pneumoniae e enterobacter spp. de pacientes internados no Hospital Universitário Professor Polydoro Ernani de São Thiago (HU/UFSC) [PDF]

, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2014.As enterobactérias são patógenos oportunistas responsáveis por cerca de 70% das infecções urinárias e
Zamparette, Caetana Paes
core  

Emergence of carbapenem-resistant hypervirulent Klebsiella pneumoniae [PDF]

The Lancet Infectious Diseases, 2018
Hong, Yao, Shangshang, Qin, Sheng, Chen, Jianzhong, Shen, Xiang-Dang, Du   +4 more
  +9 more sources

Eco‐Geography Reverses Dominant AMR Reservoirs in Klebsiella pneumoniae: Integron‐Rich Mobilomes and Cross‐Niche Connectivity

Advanced Science, Volume 13, Issue 42, 28 July 2026.
Dominant antimicrobial resistance reservoirs in Klebsiella pneumoniae vary across eco‐geographic settings rather than following a universal pattern. Integrated One Health and global genomic analyses show that lineage structure, integron load, and cross‐niche connectivity shape whether AMR burden accumulates primarily in human or nonhuman compartments ...
Hui Lin, Biao Tang, Hao Xu, Jiajie Qian, Feifan Shi, Junhui Zhao, Xiaorui Mao, Xiaohe Hu, Ruishan Liu, Wenhong Liu, Xiawei Jiang, Beiwen Zheng, Guoping Zhao   +12 more
wiley   +1 more source

Additional file 2 of Comparative in silico characterization of Klebsiella pneumoniae hypervirulent plasmids and their antimicrobial resistance genes

, 2022
Additional file 2: Table S2.
Anam Naz (800890), Negin Bolourchi (11599557), Maryam Sohrabi (12754337), Farzad Badmasti (9327920)   +3 more
core   +1 more source

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

Interdisciplinary Medicine, Volume 4, Issue 4, July 2026.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang, Zhuolin Li, Yang Yang, Zihan He, Tyuji Hoshino, Vladislav Victorovich Khrustalev, Qing Zhu, Weiling Wu, Wei Zhao, Chenguang Shen, Shi Ouyang   +10 more
wiley   +1 more source

Genomic epidemiology of carbapenem-resistant Klebsiella in Qatar: emergence and dissemination of hypervirulent Klebsiella pneumoniae sequence type 383 strains

, 2023
The emergence of carbapenem-resistant, hypervirulent Klebsiella pneumoniae is a new threat to health care. We studied the molecular epidemiology of carbapenem-resistant Klebsiella pneumoniae isolates in Qatar using whole-genome sequence data.
McElheny, Christi Lee, Doi, Yohei, Abid, Fatma Ben, Al Ismail, Khalil, Tsui, Clement Kin-Ming, Maslamani, Muna Al, Omrani, Ali S.   +6 more
core   +1 more source

Carriage of hypervirulent and ESBL-producing Klebsiella pneumoniae complex among community-dwelling individuals in Japan

Applied and Environmental Microbiology
Despite the increasing number of reports on hypervirulent and extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae infections, data on the distribution of these pathogens in the community are limited.
Akiko Watanabe, Yukio Tawada, Makoto Moriyama, Yohei Doi, Masahiro Suzuki   +4 more
doaj   +1 more source

Neutrophil function in hypervirulent Klebsiella pneumoniae infection [PDF]

The Lancet Microbe, 2022
Guan Yang, Qi Xu, Sheng Chen
openaire   +3 more sources

Retrospective cohort study of Gram-negative bacteraemia shows transmission of hypervirulent Klebsiella pneumoniae in a UK Intensive Care Unit during the Covid-19 pandemic

Infection Prevention in Practice
Background: The National incidence of bloodstream infection (BSI) caused by Klebsiella Pneumoniae increased during the Covid-19 pandemic in the United Kingdom, whilst we observed an increase in BSI caused by Gram-negative bacteria in our adult Intensive ...
Rachel Bousfield, Ruth Kappeler, Sumita Pai, Olly Allen, Kathy Randall, Jacqueline Keane, Stephen Baker   +6 more
doaj   +1 more source