Results 81 to 90 of about 128,077 (204)
Using 16,040 stool samples from healthy individuals across 30 Chinese provinces (2016–2024), we performed longitudinal genomic surveillance of carbapenem‑resistant Klebsiella pneumoniae (CRKP) colonizing the gut. We reveal rising community CRKP prevalence, especially in southern China, a shift from blaKPC‐2 to plasmid‑borne blaNDM‐5 on IncHI2/IncHI2A ...
Zelin Yan +11 more
wiley +1 more source
Metabolic Regulation of Macrophages in Health and Disease
Extracellular metabolites drive metabolic rewiring of glucose, lipid, and amino acid pathways in macrophages, steering their polarization toward pro‐ or anti‐inflammatory phenotypes and shaping a wide range of disease processes. Macrophages from different tissues display distinct metabolic signatures, and therapeutic strategies that target these ...
Shan Huang +6 more
wiley +1 more source
Neutrophil function in hypervirulent Klebsiella pneumoniae infection [PDF]
Guan Yang, Qi Xu, Sheng Chen
openaire +3 more sources
Exopolysaccharides (EPSs) are important extracellular metabolites secreted by microorganisms. Klebsiella pneumoniae is an opportunistic pathogen widely distributed in the environment, host mucosal and intestinal surfaces, and EPS from Klebsiella ...
Yuanyuan Wang +8 more
doaj +1 more source
Cong Zhou,1 Qiang Wu,1 Leqi He,1 Hui Zhang,1 Maosuo Xu,1 Baoyu Yuan,2 Zhi Jin,3 Fang Shen1 1Department of Clinical Laboratory Medicine, Shanghai Fifth People’s Hospital, Fudan University, Shanghai, People’s Republic of China; 2Department of Clinical ...
Zhou C +7 more
doaj
A 54‐year‐old healthy patient with meningitis and conjunctivitis
We describe a case report of hypermucoviscous Klebsiella pneumoniae (KP) promptly diagnosed by blood and cerebrospinal fluid (CSF) culture with positive string test.
Gilles Troché +5 more
doaj +1 more source
Thirteen‐year genomic analysis (2010–2022) reveals high‐risk ICU Pseudomonas aeruginosa in China
Abstract Pseudomonas aeruginosa is a significant opportunistic pathogen, particularly prevalent in intensive care units (ICUs). Through a comprehensive genomic and phenotypic analysis of 518 ICU and healthy isolates collected over a 13‐year period (2010–2022), we found that ICU strains, despite reduced sequence type (ST) diversity, are dominated by ...
Jiadai Huang +18 more
wiley +1 more source
Cleanliness scores as indicator of klebsiella exposure in dairy cows [PDF]
This study was designed to explore the relationship between cow and udder cleanliness scores and the risk of isolation of Klebsiella spp. from lower hind legs and teat ends, respectively. The distribution of Klebsiella species was compared among isolates
Schukken, Y. H. +11 more
core +1 more source
Epidemiologia molecolare di Klebsiella pneumoniae produttore di beta-lattamasi ad ampio spettro (ESBL) circolante in una Terapia Intensiva Neonatale [PDF]
The molecular epidemiology of extended-spectrum beta-lactamase (ESBL)-producing Klebsiella pneumoniae was investigated in the neonatal intensive care unit (NICU) of a university hospital in Italy from September 2002 to December 2004, when 233 ...
Bagattini, Maria
core +1 more source
Pre‐clinical development of two DNA vaccines encoding the MrkA fimbrial subunit of Klebsiella pneumoniae using different plasmid backbones: pVAX1 (commercial) and PLASMIVAX (with additional CpG motifs). Both DNA vaccine candidates expressed the antigen in eukaryotic cells but differed in their immunogenicity and protective efficacy against sepsis in ...
Marta Vicente‐Pazos +6 more
wiley +1 more source

