Results 81 to 90 of about 4,353 (174)

Hypervirulent Klebsiella pneumoniae ST23: Hypervirulence Meets Antimicrobial Resistance

eMicrobe
Hypervirulent Klebsiella pneumoniae can cause community-acquired invasive infections such as pyogenic liver abscess and endophthalmitis in healthy individuals compared to the classical K. pneumoniae, causing opportunistic healthcare-associated infections. Globally, K.
Atsushi Togawa, L. Kristopher Siu
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Molecular epidemiology and clinical features of Klebsiella variicola bloodstream infection compared with infection with other Klebsiella pneumoniae species complex strains

Microbiology Spectrum
Klebsiella variicola is an emerging pathogen within the Klebsiella pneumoniae species complex, and its clinical and microbiological characteristics remain poorly understood.
Tatsuya Ohno, Sohei Harada, Hiroki Saito, Rimi Tanii, Kohji Komori, Miki Kurosawa, Haruaki Wakatake, Minoru Kanazawa, Uiri Ohki, Ayu Minoura, Mario Yamada, Satsuki Kaneko, Momoko Anzai, Yuto Tsutsui, Asuka Kuhara, Tadatomo Oyanagi, Yosuke Tanaka, Hiromu Takemura, Hiroaki Takeuchi, Hiroyuki Kunishima   +19 more
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Klebsiella pneumoniae capsular polysaccharide: Mechanism in regulation of synthesis, virulence, and pathogenicity

Virulence
Hypervirulent Klebsiella pneumoniae exhibits strong pathogenicity and can cause severe invasive infections but is historically recognized as antibiotic-susceptible. In recent years, the escalating global prevalence of antibiotic-resistant hypervirulent K.
Li Xu, Jiayang Li, Wenqi Wu, Xiuwen Wu, Jianan Ren   +4 more
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Predicting Antibiotic Tolerance in hvKP and cKP Respiratory Infections Through Biofilm Formation Analysis and Its Resistance Implications

Infection and Drug Resistance
Zhongwei Wen, Yiqiang Chen, Tangjuan Liu, Jiahui Han, Yuting Jiang, Ke Zhang Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, People’s Republic of ...
Wen Z, Chen Y, Liu T, Han J, Jiang Y, Zhang K   +5 more
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A Klebsiella-phage cocktail to broaden the host range and delay bacteriophage resistance both in vitro and in vivo

npj Biofilms and Microbiomes
Bacteriophages (phages), viruses capable of infecting and lysing bacteria, are a promising alternative for treating infections from hypervirulent, antibiotic-resistant pathogens like Klebsiella pneumoniae, though narrow host range and phage resistance ...
Huanchang Chen, Haifeng Liu, Yanchun Gong, Rhys A. Dunstan, Zhexiao Ma, Cui Zhou, Deyi Zhao, Miran Tang, Trevor Lithgow, Tieli Zhou   +9 more
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A capsule-dependent lytic phage for targeting multidrug-resistant and hypervirulent Klebsiella pneumoniae

Applied and Environmental Microbiology
As the threat of multidrug-resistant Klebsiella pneumoniae strains rises, the potential of phages as promising alternatives to antibiotics is increasingly being demonstrated.
Ziyan Tian, Lin Gan, Junxia Feng, Guanhua Xue, Bing Du, Jinghua Cui, Chao Yan, Hanqing Zhao, Yanling Feng, Zheng Fan, Tongtong Fu, Ziying Xu, Zihui Yu, Yang Yang, Ke Yuehua, Xiaohu Cui, Zhijie Tang, Jing Yuan   +17 more
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Treatment of liver abscess caused by Klebsiella pneumoniae with multi-site infection: a case report

Journal of Medical Case Reports
Background Pyogenic liver abscesses are a fatal condition often seen in emergency departments. The major clinical presentations include weakness, anorexia, fever, chills, ventosity and abdominal pain.
Yong-gang Gui, Song-tao Shou, Yi Jiang, Qiu-ling Wang   +3 more
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Mobile genetic elements encoding antibiotic resistance genes and virulence genes in Klebsiella pneumoniae: important pathways for the acquisition of virulence and resistance

Frontiers in Microbiology
Klebsiella pneumoniae is an opportunistic pathogen primarily associated with nosocomial infections, characterized by a propensity for multi-drug resistance and the potential evolution into hypervirulent strains.
Bin Han, Bin Han, Bin Han, Bin Han, Chunlin Feng, Chunlin Feng, Chunlin Feng, Yuan Jiang, Yuan Jiang, Yuan Jiang, Caihong Ye, Caihong Ye, Caihong Ye, Yueshuai Wei, Yueshuai Wei, Yueshuai Wei, Jinbo Liu, Jinbo Liu, Jinbo Liu, Jinbo Liu, Zhangrui Zeng, Zhangrui Zeng, Zhangrui Zeng   +22 more
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A novel depolymerase encoded by phage P5054 specifically degrades the K57-type capsular polysaccharide of Klebsiella pneumoniae

One Health Advances
Klebsiella pneumoniae is an important pathogen, especially hypervirulent and multidrug-resistant K. pneumoniae, which are increasingly becoming a serious threat to global public health.
Heyuan Lun, Juanjuan Wang, Huagen Chen, Heng Li, Ruijing Ma, Yuqing Pan, Tingting Qu, Aixi Wang, Kai He, Jingran Yu, Ping He   +10 more
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[Meningitis and myelitis by hypervirulent Klebsiella pneumoniae].

Medicina
Invasive liver abscess syndrome caused by hypervirulent Klebsiella. pneumoniae is a rare disease. This type of K. pneumoniae is aggressive and invasive, despite its sensitivity profile. We report the case of a 62-year-old man with diabetes mellitus, who was admitted to our hospital with meningeal syndrome.
María Vanesa, Durán, María Fernanda, Landaburu, Mariana, Scarabino, María José, López Furst   +3 more
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