Results 101 to 110 of about 7,114 (212)

A promising bioconjugate vaccine against hypervirulent Klebsiella pneumoniae

Proceedings of the National Academy of Sciences, 2019
Significance Klebsiella pneumoniae is considered a nosocomial pathogen, usually infecting immunocompromised patients. However, a pathotype of K. pneumoniae , termed hypervirulent K. pneumoniae (hv Kp ), has emerged and is spreading throughout the ...
Mario F. Feldman, Anne E. Mayer Bridwell, Nichollas E. Scott, Evgeny Vinogradov, Samuel R. McKee, Sthefany M. Chavez, Joy Twentyman, Christina L. Stallings, David A. Rosen, Christian M. Harding   +9 more
openaire   +3 more sources

Hypervirulent Klebsiella pneumoniae: a new public health threat [PDF]

Expert Review of Anti-infective Therapy, 2018
Hypervirulent Klebsiella pneumoniae (hvKp) is an increasingly recognized pathotype of K. pneumoniae characterized clinically by its ability to cause organ- or life-threatening infections in healthy...
Candace M, Marr, Thomas A, Russo
openaire   +2 more sources

Genomic Evolution of the Increasing Prevalent Carbapenem‐Resistant Hypervirulent ST15 Klebsiella pneumoniae

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
Purpose ST15 Klebsiella pneumoniae (Kp) is increasingly prevalent in China and worldwide. Currently, the mechanisms underlying the acquisition of hypervirulence‐associated genes in sequence Type 15 (ST15) Kp are still not well studied. The global prevalence of ST15 Kp is increasing, alongside notable increases in both resistance and virulence.
Shuaihua Fan, Pengcheng Du, Yunfei Tang, Huaiqing Qi, Chao Liu, Jun Guo, Mohamed Salah Abbassi   +6 more
wiley   +1 more source

Carriage of hypervirulent and ESBL-producing Klebsiella pneumoniae complex among community-dwelling individuals in Japan

Applied and Environmental Microbiology
Despite the increasing number of reports on hypervirulent and extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae infections, data on the distribution of these pathogens in the community are limited.
Akiko Watanabe, Yukio Tawada, Makoto Moriyama, Yohei Doi, Masahiro Suzuki   +4 more
doaj   +1 more source

Antimicrobial Resistant Factors in Klebsiella pneumoniae Strains Isolated From Urinary Tract Infections, Wound Infections, Hospital Wastewater, and Cervical Cancers From Ghana, Togo, and Benin

International Journal of Genomics, Volume 2026, Issue 1, 2026.
Klebsiella pneumoniae is a Gram‐negative, facultatively anaerobic member of the Enterobacteriaceae that functions both as a gut commensal and a major opportunistic pathogen implicated in severe hospital and community‐acquired infections. The rapid global expansion of antimicrobial‐resistant K.
Biigba Yakubu, Santasree Banerjee
wiley   +1 more source

Retrospective cohort study of Gram-negative bacteraemia shows transmission of hypervirulent Klebsiella pneumoniae in a UK Intensive Care Unit during the Covid-19 pandemic

Infection Prevention in Practice
Background: The National incidence of bloodstream infection (BSI) caused by Klebsiella Pneumoniae increased during the Covid-19 pandemic in the United Kingdom, whilst we observed an increase in BSI caused by Gram-negative bacteria in our adult Intensive ...
Rachel Bousfield, Ruth Kappeler, Sumita Pai, Olly Allen, Kathy Randall, Jacqueline Keane, Stephen Baker   +6 more
doaj   +1 more source

An Outbreak of Carbapenem-Resistant and Hypervirulent Klebsiella pneumoniae in an Intensive Care Unit of a Major Teaching Hospital in Wenzhou, China [PDF]

, 2019
Carbapenem-resistant, hypervirulent Klebsiella pneumoniae (CR-hvKP) has recently emerged as a significant threat to public health. In this study, 29 K. pneumoniae isolates were isolated from eight patients admitted to the intensive care unit (ICU) of a ...
Bi, Wenzi, Cao, Jianming, Chen, Lijiang, Lin, Jie, Lithgow, Trevor, Liu, Haiyang, Rocker, Andrea, Strugnell, Richard A., Torres, Von Vergel L., Wang, Jiawei, Zhang, Siqin, Zhang, Xiucai, Zhang, Yizhi, Zhao, Yajie, Zhou, Tieli   +14 more
core   +2 more sources

Antimicrobial Resistance, Virulence, and Genomic Characteristics of Klebsiella pneumoniae Isolated From Four Host Sources in Northeast China

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Klebsiella pneumoniae is an important emerging pathogen leading to serious clinical outcomes as the multidrug‐resistant (MDR) isolates arise. While K. pneumoniae is a well‐known pathogen in human clinical settings, its risks in nonhuman hosts and potential for cross‐species transmission remain poorly understood. In this study, we performed whole‐genome
Qiu Xu, Cuilong Fan, Yaowei Liu, Xiaofeng Lu, Wei Song, Susu Du, Yao Zhu, Fang Xie, Wanjiang Zhang, Zhong Peng   +9 more
wiley   +1 more source

Neutrophil function in hypervirulent Klebsiella pneumoniae infection [PDF]

The Lancet Microbe, 2022
Guan Yang, Qi Xu, Sheng Chen
openaire   +3 more sources

Evolutionary Origins and Virulence Determinants of ST25 Hypervirulent Klebsiella pneumoniae in Swine: Genomic Insights and Functional Validation

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The global spread of multidrug‐resistant hypervirulent Klebsiella pneumoniae (MDR‐HvKp), among which carbapenem‐resistant strains are of major concern, poses a severe threat to public health due to its high mortality rate and extremely limited treatment options.
Zheng Chen, Yang Liu, Congyang Du, Shengguo Gao, Lufeng Zhai, Stefan Schwarz, Weicheng Liu, Qiong Li, Longyu Li, Runhao Yu, Yuzhe Zhao, Hong Yao, Lei Luo, Xue Liu, Chunyan Xu, Xiang-Dang Du, Zongfu Wu   +16 more
wiley   +1 more source