Results 71 to 80 of about 115,878 (208)

Carbapenem-Resistant Hypervirulent Klebsiella pneumoniae of Sequence Type 36

, 2018
Sequence type 36 (ST36) Klebsiella pneumoniae is distributed worldwide. We found an ST36 K. pneumoniae clinical isolate that was carbapenem resistant, carried bla KPC-2 ,
Zhiyong Zong, Yang Lu, Yu Feng, Zhihong Yao   +3 more
core   +1 more source

Arginine regulates the mucoid phenotype of hypervirulent Klebsiella pneumoniae. [PDF]

Nat Commun
Hypervirulent Klebsiella pneumoniae causes severe community-acquired infections, with its mucoid phenotype resulting from altered capsular polysaccharide chain length. While both environmental and genetic factors influence mucoidy, the cues regulating it remain unclear.
Ryan BE, Holmes CL, Stark DJ, Shepard GE, Mills EG, Khadka S, Van Tyne D, Bachman MA, Mike LA.   +8 more
europepmc   +3 more sources

Genomic Epidemiology of Multidrug‐Resistant Clinical Klebsiella pneumoniae From Pakistan

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Study design and bioinformatics workflow. Cohort selection and uniform workflow. ABSTRACT Background Antimicrobial‐resistant Klebsiella pneumoniae is a major clinical threat in Pakistan and the wider South Asian region, where genomic surveillance remains limited. We analyzed 122 publicly available human clinical K.
Hakeem Zada, Muhammad Qasim, Mubashir Hussain, Abdul Rehman, Hassan Naveed, Noor Bahadar, Najibullah Anwari   +6 more
wiley   +1 more source

Bacteriophages with depolymerase activity in the control of antibiotic resistant Klebsiella pneumoniae biofilms

Scientific Reports, 2023
Klebsiella pneumoniae is associated with a variety of infections, such as pneumonia, urogenital infection, liver abscess, and bloodstream infection. It is especially dangerous for patients in medical facilities, where it can cause ventilator-associated ...
Fedor Zurabov, Egor Glazunov, Tatiana Kochetova, Viktoria Uskevich, Valentina Popova   +4 more
doaj   +1 more source

Longitudinal Molecular Epidemiology and Genomic Surveillance of Carbapenem‐Resistant Klebsiella pneumoniae in the Gut of Healthy Individuals in China

MedComm, Volume 7, Issue 8, August 2026.
Using 16,040 stool samples from healthy individuals across 30 Chinese provinces (2016–2024), we performed longitudinal genomic surveillance of carbapenem‑resistant Klebsiella pneumoniae (CRKP) colonizing the gut. We reveal rising community CRKP prevalence, especially in southern China, a shift from blaKPC‐2 to plasmid‑borne blaNDM‐5 on IncHI2/IncHI2A ...
Zelin Yan, Yan Li, Yi Sun, Qiaoling Sun, Congcong Liu, Yanyan Zhang, Yuchen Wu, Hongwei Zhou, Shangshang Qin, Gongxiang Chen, Ruichao Li, Rong Zhang   +11 more
wiley   +1 more source

Metabolic Regulation of Macrophages in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
Extracellular metabolites drive metabolic rewiring of glucose, lipid, and amino acid pathways in macrophages, steering their polarization toward pro‐ or anti‐inflammatory phenotypes and shaping a wide range of disease processes. Macrophages from different tissues display distinct metabolic signatures, and therapeutic strategies that target these ...
Shan Huang, Yu Zhang, Jiali Min, Jiahui Yang, Yuchen Li, Hao Zhang, Shanshan Liu   +6 more
wiley   +1 more source

Thirteen‐year genomic analysis (2010–2022) reveals high‐risk ICU Pseudomonas aeruginosa in China

mLife, Volume 5, Issue 4, Page 459-472, August 2026.
Abstract Pseudomonas aeruginosa is a significant opportunistic pathogen, particularly prevalent in intensive care units (ICUs). Through a comprehensive genomic and phenotypic analysis of 518 ICU and healthy isolates collected over a 13‐year period (2010–2022), we found that ICU strains, despite reduced sequence type (ST) diversity, are dominated by ...
Jiadai Huang, Kaichao Chen, Miaomiao Xie, Weiyi Shen, Xiaoyang Ju, Yuchen Wu, Jiaping Li, Hongwei Zhou, Yonglu Huang, Yizhou Zhang, Yuanfeng Zhang, Tianmin Li, Letong Xu, Yue Sun, Fang Chen, Sheng Chen, Xin Deng, Rong Zhang, Yanyan Hu   +18 more
wiley   +1 more source

Tea-Residue-Derived Klebsiella pneumoniae CGMCC 31459: Genomic Insights and Antioxidant Activity of Its Exopolysaccharides

Biomolecules
Exopolysaccharides (EPSs) are important extracellular metabolites secreted by microorganisms. Klebsiella pneumoniae is an opportunistic pathogen widely distributed in the environment, host mucosal and intestinal surfaces, and EPS from Klebsiella ...
Yuanyuan Wang, Shengbo Shi, Mingchun Lin, Gangrui Zhang, Longyu Fang, Jinghua Li, Rui Geng, Yuanxue Zheng, Lujiang Hao   +8 more
doaj   +1 more source

Clinical and Molecular Characteristics of Carbapenem-Resistant Hypervirulent Klebsiella pneumoniae Isolates in a Tertiary Hospital in Shanghai, China

Infection and Drug Resistance, 2021
Cong Zhou,1 Qiang Wu,1 Leqi He,1 Hui Zhang,1 Maosuo Xu,1 Baoyu Yuan,2 Zhi Jin,3 Fang Shen1 1Department of Clinical Laboratory Medicine, Shanghai Fifth People’s Hospital, Fudan University, Shanghai, People’s Republic of China; 2Department of Clinical ...
Zhou C, Wu Q, He L, Zhang H, Xu M, Yuan B, Jin Z, Shen F   +7 more
doaj  

A 54‐year‐old healthy patient with meningitis and conjunctivitis

Journal of the American College of Emergency Physicians Open, 2021
We describe a case report of hypermucoviscous Klebsiella pneumoniae (KP) promptly diagnosed by blood and cerebrospinal fluid (CSF) culture with positive string test.
Gilles Troché, Amandine Henry, Florence Sarfati, Charles Hickel, Marlène Amara, Fabrice Bruneel   +5 more
doaj   +1 more source