Results 71 to 80 of about 128,077 (204)

Convergence of carbapenem resistance and hypervirulence leads to high mortality in patients with postoperative Klebsiella pneumoniae meningitis

Journal of Global Antimicrobial Resistance, 2021
: Objectives: The aims of this study were to investigate the characteristics of Klebsiella pneumoniae meningitis and the impact of convergence of carbapenem resistance and hypervirulence on patient mortality.Methods: Antimicrobial resistance and ...
Yuming Li, Dakang Hu, Xiaobo Ma, Dan Li, Dongxing Tian, Ye Gong, Xiaofei Jiang   +6 more
doaj   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source

Additional file 1: of Diversity of virulence level phenotype of hypervirulent Klebsiella pneumoniae from different sequence type lineage

, 2018
Figure S1. The density graph of LD50 of 56 hypervirulent Klebsiella pneumoniae isolates.
Xiaoting Hua (435699), Danyan Huang (5148011), Jiancang Zhou (3233460), Qiucheng Shi (3233457), Yunsong Yu (496103), Peng Lan (5699819), Yan Jiang (12139)   +6 more
core   +1 more source

Interpretation of Key Updates in the 36th Edition of Clinical and Laboratory Standards Institute M100 Standard

iLABMED, Volume 4, Issue 3, Page 133-138, September 2026.
ABSTRACT The Clinical and Laboratory Standards Institute M100 document serves as a cornerstone standard for clinical microbiology laboratories in China. Maintaining the scientific rigor of its predecessors, the 36th edition incorporates updated epidemiological cutoff values, pharmacokinetic/pharmacodynamic data, and clinical efficacy evidence to revise
Kanghong Xu, Qi Wang, Hui Wang
wiley   +1 more source

Genome assemblies: Horizontal transfer of pOXA-48 from a hypervirulent Klebsiella pneumoniae ST23/KL57 to Serratia marcescens

, 2023
Hypervirulent Klebsiella pneumonia isolates express a range of virulence factors, often encoded on virulence plasmids. Occasionally these hypervirulent lineages acquire antimicrobial resistance genes rendering them multidrug-resistant.
Maria-Anna Misiakou, Kristian Schønning, Henrik Hasman, Karen Leth Nielsen, Susanne Häussler, Marc Sørensen, Frederik Boëtius Hertz, Marie Helleberg   +7 more
core   +1 more source

Whole Genome Characterization of Klebsiella Strains in European Hedgehogs and Human Nosocomial Settings Identified Shared Sequence Types, Antimicrobial Resistance Genes and Plasmids

Zoonoses and Public Health, Volume 73, Issue 6, Page 516-527, September 2026.
ABSTRACT Introduction Klebsiella pneumoniae is a pathogen associated with healthcare‐acquired infections and antimicrobial resistance (AMR) to beta‐lactams and carbapenems. Although wild animals are not typically exposed to antibiotics, they can harbour resistant strains. The European hedgehog (Erinaceus europaeus) is increasingly found in urban areas,
Biel Garcias, Chiara Seminati, Carolin M. Kobras, Samuel K. Sheppard, Rafael A. Molina‐López, Laila Darwich   +5 more
wiley   +1 more source

Bacteriophages with depolymerase activity in the control of antibiotic resistant Klebsiella pneumoniae biofilms

Scientific Reports, 2023
Klebsiella pneumoniae is associated with a variety of infections, such as pneumonia, urogenital infection, liver abscess, and bloodstream infection. It is especially dangerous for patients in medical facilities, where it can cause ventilator-associated ...
Fedor Zurabov, Egor Glazunov, Tatiana Kochetova, Viktoria Uskevich, Valentina Popova   +4 more
doaj   +1 more source

Genomic Epidemiology of Multidrug‐Resistant Clinical Klebsiella pneumoniae From Pakistan

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Study design and bioinformatics workflow. Cohort selection and uniform workflow. ABSTRACT Background Antimicrobial‐resistant Klebsiella pneumoniae is a major clinical threat in Pakistan and the wider South Asian region, where genomic surveillance remains limited. We analyzed 122 publicly available human clinical K.
Hakeem Zada, Muhammad Qasim, Mubashir Hussain, Abdul Rehman, Hassan Naveed, Noor Bahadar, Najibullah Anwari   +6 more
wiley   +1 more source

Klebsiella pneumoniae in Singapore: Hypervirulent Infections and the Carbapenemase Threat [PDF]

Frontiers in Cellular and Infection Microbiology, 2017
Klebsiella pneumoniae remains a major pathogen responsible for localized infections such as cystitis and pneumonia, and disseminated infections that may result in severe sepsis and death. Invasive disease such as liver abscesses and endogenous endophthalmitis are associated with capsular serotypes K1 and K2.
Ka Lip Chew, Raymond T. P. Lin, Raymond T. P. Lin, Jeanette W. P. Teo   +3 more
openaire   +3 more sources

Emergence of carbapenem-resistant hypervirulent Klebsiella pneumoniae [PDF]

The Lancet Infectious Diseases, 2018
Pengcheng, Du, Yuanyuan, Zhang, Chen, Chen   +2 more
  +9 more sources