Results 41 to 50 of about 7,114 (212)

A global perspective on the convergence of hypervirulence and carbapenem resistance in Klebsiella pneumoniae

open access: yesJournal of Global Antimicrobial Resistance, 2021
Hypervirulence and carbapenem resistance have emerged as two distinct evolutionary directions for Klebsiella pneumoniae, which pose a great threat in clinical settings.
Peng Lan   +3 more
doaj   +1 more source

Exploring dangerous connections between Klebsiella pneumoniae biofilms and healthcare-associated infections [PDF]

open access: yes, 2014
Healthcare-associated infections (HAI) are a huge public health concern,particularly when the etiological agents are multidrug resistant. The ability of bacteria to develop biofilm is a helpful skill, both to persist within hospital units and to ...
Bandeira, Maria   +3 more
core   +2 more sources

Hypervirulent (hypermucoviscous)Klebsiella pneumoniae [PDF]

open access: yesVirulence, 2013
A new hypervirulent (hypermucoviscous) variant of Klebsiella pneumoniae has emerged. First described in the Asian Pacific Rim, it now increasingly recognized in Western countries. Defining clinical features are the ability to cause serious, life-threatening community-acquired infection in younger healthy hosts, including liver abscess, pneumonia ...
Shon, Alyssa S.   +2 more
openaire   +2 more sources

Community-acquired liver abscess caused by capsular genotype K2-ST375 hypervirulent Klebsiella pneumoniae isolates

open access: yesIDCases, 2019
Hypervirulent Klebsiella pneumoniae has been associated with community-acquired liver abscesses in relatively healthy subjects since the 1990s, occasionally accompanied by disseminated disease. While isolates of capsular genotype K1 belonging to sequence
Kosuke Hoashi   +6 more
doaj   +1 more source

Transmission of Nonconjugative Virulence or Resistance Plasmids Mediated by a Self-Transferable IncN3 Plasmid from Carbapenem-Resistant Klebsiella pneumoniae

open access: yesMicrobiology Spectrum, 2022
Klebsiella pneumoniae poses a critical challenge to clinical and public health. Along with conjugative plasmids, nonconjugative resistance or virulence plasmids associated with carbapenem-resistant K. pneumoniae (CRKP), hypervirulent K. pneumoniae (hvKP),
Xiaoli Wang   +10 more
doaj   +1 more source

Antimicrobial-resistant Gram-negative infections in neonates: burden of disease and challenges in treatment. [PDF]

open access: yes, 2017
PURPOSE OF REVIEW: This review summarizes the main challenges of antimicrobial resistance (AMR) in the neonatal population with a special focus on multidrug-resistant (MDR) Gram-negative pathogens.
Bielicki, J   +3 more
core   +1 more source

Whole genome sequencing reveals high-resolution epidemiological links between clinical and environmental Klebsiella pneumoniae. [PDF]

open access: yes, 2017
BACKGROUND: Klebsiella pneumoniae is a gram-negative bacterial species capable of occupying a broad range of environmental and clinical habitats. Known as an opportunistic pathogen, it has recently become a major causative agent of clinical infections ...
Anun, Suthatip   +8 more
core   +3 more sources

Phage-borne depolymerases decrease Klebsiella pneumoniae resistance to innate defense mechanisms [PDF]

open access: yes, 2018
Klebsiella pneumoniae produces capsular polysaccharides that are a crucial virulence factor protecting bacteria against innate response mechanisms of the infected host.
Agnieszka Latka   +7 more
core   +5 more sources

Characterization of hypervirulent Klebsiella pneumoniae isolates in Belgium

open access: yesEuropean Journal of Clinical Microbiology & Infectious Diseases, 2022
Hypervirulent Klebsiella pneumoniae (hvKp) raised concern worldwide. We studied 22 hvKp clinical invasive isolates referred to the Belgian national reference laboratory between 2014 and 2020. Sixty-four percent of the isolates expressed K2 capsular serotype and belonged to 7 different MLST lineages, while 32% expressed K1 (all belonging to ST23) and ...
Anantharajah, Ahalieyah   +12 more
openaire   +4 more sources

Structure, Genetics and Worldwide Spread of New Delhi Metallo-β-lactamase (NDM): a threat to public health [PDF]

open access: yes, 2017
Background: The emergence of carbapenemase producing bacteria, especially New Delhi metallo-β-lactamase (NDM-1) and its variants, worldwide, has raised amajor public health concern.
Khan, Asad U   +2 more
core   +1 more source

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