Hypervirulent Klebsiella pneumoniae has been associated with community-acquired liver abscesses in relatively healthy subjects since the 1990s, occasionally accompanied by disseminated disease. While isolates of capsular genotype K1 belonging to sequence
Kosuke Hoashi +6 more
doaj +2 more sources
First report of invasive liver abscess syndrome with endophthalmitis caused by a K2 serotype ST2398 hypervirulent Klebsiella pneumoniae in Germany, 2016 [PDF]
We report a case of severe infection with liver abscess and endophthalmitis caused by a hypervirulent Klebsiella pneumoniae strain in an immunocompetent German male patient without travel history to Asia.
C. Pichler +7 more
doaj +2 more sources
Characterization of hypervirulent Klebsiella pneumoniae isolates in Belgium.
Hypervirulent Klebsiella pneumoniae (hvKp) raised concern worldwide. We studied 22 hvKp clinical invasive isolates referred to the Belgian national reference laboratory between 2014 and 2020.
Hallin, Marie +28 more
core +4 more sources
What defines hypervirulent Klebsiella pneumoniae? [PDF]
Thomas D. Stanton, Kelly L. Wyres
doaj +4 more sources
Different gut microbiome dysbioses impact the evolutionary fate of hypervirulent Klebsiella pneumoniae [PDF]
Transient exposure to ampicillin results in restructuring of microbiota to favor oxygen‐tolerant bacteria, whereas osmotic laxative perturbation preserves Bacteriodota. Ampicillin‐ but not laxative‐exposed environment favors establishment of rmpA phase variants that lost hypermucoviscosity but short‐chain fatty acids present in the laxative‐exposed gut
Carey Lim +9 more
wiley +2 more sources
Genomic Analysis of Hypervirulent <i>Klebsiella pneumoniae</i> ST1-KL122. [PDF]
Hypervirulent Klebsiella pneumoniae (hvKp) is often characterized by hypervirulence and hypermucoviscosity, traits classically associated with the virulence regulators rmpA and rmpA2. However, some clinically virulent isolates lack these canonical regulators, suggesting the existence of non-canonical pathways driving hypervirulence.This study aimed to ...
Yang Y +7 more
europepmc +3 more sources
A Step Forward in Hypervirulent Klebsiella pneumoniae Diagnostics. [PDF]
Hypervirulent Klebsiella pneumoniae (hvKp) can cause life-threatening infections in healthy community members. HvKp infections often involve multiple sites, some of which are unusual for classical K. pneumoniae (cKp) infections, such as the central nervous system, eyes, and fascia.
Russo TA, Lebreton F, McGann PT.
europepmc +4 more sources
Arginine regulates the mucoid phenotype of hypervirulent Klebsiella pneumoniae. [PDF]
Hypervirulent Klebsiella pneumoniae causes severe community-acquired infections, with its mucoid phenotype resulting from altered capsular polysaccharide chain length. While both environmental and genetic factors influence mucoidy, the cues regulating it remain unclear.
Ryan BE +8 more
europepmc +3 more sources
Multiple metastatic infections due to hypervirulent <i>Klebsiella pneumoniae</i>. [PDF]
Hypervirulent Klebsiella pneumoniae (hvKp) was first identified in Taiwan in 1986, and has emerged as a leading cause of severe community-acquired infections, particularly in Asia. Its metastatic nature, often involving the liver and eyes, poses significant diagnostic challenges and is associated with substantial morbidity.A 47-year-old Taiwanese man ...
You TY, Kuo PC, Chen SY, Su SL, Ko WC.
europepmc +3 more sources
Case Study and Genomic Analysis of a Hypervirulent ST25 Klebsiella pneumoniae Strain in a Liver Cirrhosis Patient [PDF]
Yizhang Wang Department of Clinical Laboratory, Sanmen People’s Hospital, Sanmen, Zhejiang, People’s Republic of ChinaCorrespondence: Yizhang Wang, Department of Clinical Laboratory, Sanmen People’s Hospital, No.
Wang Y
doaj +1 more source

