Results 21 to 30 of about 7,114 (212)

Sputum Gram stain of hypervirulent Klebsiella pneumoniae

Journal of General and Family Medicine, 2023
Hypervirulent Klebsiella pneumoniae has virulence genes relevant to capsule overproduction, which could lead to the finding of thick transparent area ("halo") in Gram stain. In sputum Gram stain, observation of a large Gram-negative rod with a thick capsule may not only indicate that it is K. pneumoniae but also that it is a highly virulent strain.
Yuji Nishihara, Takahito Nakamura, Yuki Suzuki, Kei Kasahara   +3 more
openaire   +3 more sources

Carbapenem Resistance Conferred by OXA-48 in K2-ST86 Hypervirulent Klebsiella pneumoniae, France

Emerging Infectious Diseases, 2020
We recovered 2 carbapenem-resistant K2-ST86 hypermucoviscous Klebsiella pneumoniae isolates from patients in France. The isolates had genetic attributes of hypervirulent K. pneumoniae but differed in ability to cause mouse lethality.
Racha Beyrouthy, Guillaume Dalmasso, Aurélien Birer, Frédéric Robin, Richard Bonnet   +4 more
doaj   +1 more source

Acquisition of regulator on virulence plasmid of hypervirulent Klebsiella allows bacterial lifestyle switch in response to iron

mBio, 2023
Hypervirulent Klebsiella pneumoniae causes liver abscess and potentially devastating metastatic complications. The majority of Klebsiella-induced liver abscess are caused by the CG23-I sublineage of hypervirulent Klebsiella pneumoniae.
Wilson H. W. Chu, Yi Han Tan, Si Yin Tan, Yahua Chen, Melvin Yong, David C. Lye, Shirin Kalimuddin, Sophia Archuleta, Yunn-Hwen Gan   +8 more
doaj   +1 more source

Unusual Hypermucoviscous Clinical Isolate of Klebsiella pneumoniae with No Known Determinants of Hypermucoviscosity

Microbiology Spectrum, 2022
Klebsiella pneumoniae can be broadly classified into classical strains that cause drug-resistant, hospital-associated infections and hypervirulent strains that cause invasive, community-acquired, drug-susceptible infections.
Tamal Dey, Ardhendu Chakrabortty, Aastha Kapoor, Anuja Warrier, Vijaya Lakshmi Nag, Karthikeyan Sivashanmugam, Manoharan Shankar   +6 more
doaj   +1 more source

Tracking key virulence loci encoding aerobactin and salmochelin siderophore synthesis in Klebsiella pneumoniae. [PDF]

, 2018
BACKGROUND: Klebsiella pneumoniae is a recognised agent of multidrug-resistant (MDR) healthcare-associated infections; however, individual strains vary in their virulence potential due to the presence of mobile accessory genes.
Brisse, Sylvain, Holt, Kathryn E, Jenney, Adam, Judd, Louise M, Lam, Margaret MC, Wick, Ryan R, Wyres, Kelly L   +6 more
core   +8 more sources

Molecular Epidemiology of Hypervirulent Carbapenemase-Producing Klebsiella pneumoniae [PDF]

Frontiers in Cellular and Infection Microbiology, 2021
ObjectiveTo investigate the overall distributions of key virulence genes in Klebsiella pneumoniae, especially the hypervirulent blaKPC-positive K. pneumoniae (Hv-blaKPC(+)-KP).MethodsA total of 521 complete genomes of K. pneumoniae from GenBank were collected and analyzed.
Dakang Hu, Yuming Li, Ping Ren, Dongxing Tian, Wenjie Chen, Pan Fu, Pan Fu, Weiwen Wang, Xiaobin Li, Xiaofei Jiang   +9 more
openaire   +3 more sources

Community-acquired invasive liver abscess syndrome caused by a K1 serotype Klebsiella pneumoniae isolate in Brazil: a case report of hypervirulent ST23 [PDF]

, 2014
Universidade Federal de São Paulo (UNIFESP) Departamento de MedicinaUniversidade Federal de São Paulo (UNIFESP) Departamento de Medicina Divisão de Doenças InfecciosasUNIFESP, Depto. de MedicinaUNIFESP, Depto.
Coutinho, Rosane L, Descio, Fernanda J, Furtado, Guilherme Hc, Gales, Ana Cristina, Nicoletti, Adriana Giannini, Pinto, Flavia Cl, Rodrigues-costa, Fernanda, Silva, Ana Carolina R da, Visconde, Marina F   +8 more
core   +3 more sources

Combing Immunoinformatics with Pangenome Analysis To Design a Multiepitope Subunit Vaccine against Klebsiella pneumoniae K1, K2, K47, and K64

Microbiology Spectrum, 2022
Klebsiella pneumoniae is an opportunistic Gram-negative bacterium that has become a leading causative agent of nosocomial infections, mainly infecting patients with immunosuppressive diseases.
Zhuohao Wang, Genglin Guo, Quan Li, Pei Li, Min Li, Lu Zhou, Zhongming Tan, Wei Zhang   +7 more
doaj   +1 more source

Characterization of a multidrug-resistant porcine Klebsiella pneumoniae sequence type 11 strain coharboring blaKPC-2 and fosA3 on two novel hybrid plasmids [PDF]

, 2019
The occurrence of carbapenemase-producing Enterobacteriaceae (CPE) poses a considerable risk for public health. The gene for Klebsiella pneumoniae carbapenemase-2 (KPC-2) has been reported in many countries worldwide, and KPC-2-producing strains are ...
Chen, Fuguang, Li, Ruichao, Liu, Siguo, Liu, Wenyu, Luan, Tian, Schwarz, Stefan, Wang, Changzhen, Zhang, Wanjiang, Zhang, Yanhe, Zhu, Yao   +9 more
core   +1 more source

Colonization, Infection, and the Accessory Genome of Klebsiella pneumoniae

Frontiers in Cellular and Infection Microbiology, 2018
Klebsiella pneumoniae is a Gram-negative pathogen that has a large accessory genome of plasmids and chromosomal gene loci. This accessory genome divides K. pneumoniae strains into opportunistic, hypervirulent, and multidrug-resistant groups and separates
Rebekah M. Martin, Michael A. Bachman
doaj   +1 more source