Results 21 to 30 of about 4,353 (174)

Acquisition of regulator on virulence plasmid of hypervirulent Klebsiella allows bacterial lifestyle switch in response to iron

mBio, 2023
Hypervirulent Klebsiella pneumoniae causes liver abscess and potentially devastating metastatic complications. The majority of Klebsiella-induced liver abscess are caused by the CG23-I sublineage of hypervirulent Klebsiella pneumoniae.
Wilson H. W. Chu, Yi Han Tan, Si Yin Tan, Yahua Chen, Melvin Yong, David C. Lye, Shirin Kalimuddin, Sophia Archuleta, Yunn-Hwen Gan   +8 more
doaj   +1 more source

Unusual Hypermucoviscous Clinical Isolate of Klebsiella pneumoniae with No Known Determinants of Hypermucoviscosity

Microbiology Spectrum, 2022
Klebsiella pneumoniae can be broadly classified into classical strains that cause drug-resistant, hospital-associated infections and hypervirulent strains that cause invasive, community-acquired, drug-susceptible infections.
Tamal Dey, Ardhendu Chakrabortty, Aastha Kapoor, Anuja Warrier, Vijaya Lakshmi Nag, Karthikeyan Sivashanmugam, Manoharan Shankar   +6 more
doaj   +1 more source

Characterization of hypervirulent Klebsiella pneumoniae isolates in Belgium

European Journal of Clinical Microbiology & Infectious Diseases, 2022
Hypervirulent Klebsiella pneumoniae (hvKp) raised concern worldwide. We studied 22 hvKp clinical invasive isolates referred to the Belgian national reference laboratory between 2014 and 2020. Sixty-four percent of the isolates expressed K2 capsular serotype and belonged to 7 different MLST lineages, while 32% expressed K1 (all belonging to ST23) and ...
Anantharajah, Ahalieyah, Deltombe, Matthieu, de Barsy, Marie, Evrard, Stephanie, Denis, Olivier, Bogaerts, Pierre, Hallin, Marie, Miendje Deyi, Véronique Yvette, Piérard, Denis, Bruynseels, Peggy, Boelens, Jerina, Glupczynski, Youri, Huang, Te-Din   +12 more
openaire   +4 more sources

Analysis of hypervirulent Klebsiella pneumoniae and classic Klebsiella pneumoniae infections in a Chinese hospital [PDF]

Journal of Applied Microbiology, 2022
Abstract Aims To evaluate the clinical and genetic virulence characteristics of critically ill patients with hypervirulent Klebsiella pneumoniae (hvKP) and classic KP (cKP) infection. Methods and Results The patients included in this ...
Dongjie Chen, Yingrui Zhang, Jiafang Wu, Jun Li, Han Chen, Xiaoguang Zhang, Xinlan Hu, Falin Chen, Rongguo Yu   +8 more
openaire   +2 more sources

Combing Immunoinformatics with Pangenome Analysis To Design a Multiepitope Subunit Vaccine against Klebsiella pneumoniae K1, K2, K47, and K64

Microbiology Spectrum, 2022
Klebsiella pneumoniae is an opportunistic Gram-negative bacterium that has become a leading causative agent of nosocomial infections, mainly infecting patients with immunosuppressive diseases.
Zhuohao Wang, Genglin Guo, Quan Li, Pei Li, Min Li, Lu Zhou, Zhongming Tan, Wei Zhang   +7 more
doaj   +1 more source

Colonization, Infection, and the Accessory Genome of Klebsiella pneumoniae

Frontiers in Cellular and Infection Microbiology, 2018
Klebsiella pneumoniae is a Gram-negative pathogen that has a large accessory genome of plasmids and chromosomal gene loci. This accessory genome divides K. pneumoniae strains into opportunistic, hypervirulent, and multidrug-resistant groups and separates
Rebekah M. Martin, Michael A. Bachman
doaj   +1 more source

First report of invasive liver abscess syndrome with endophthalmitis caused by a K2 serotype ST2398 hypervirulent Klebsiella pneumoniae in Germany, 2016

New Microbes and New Infections, 2017
We report a case of severe infection with liver abscess and endophthalmitis caused by a hypervirulent Klebsiella pneumoniae strain in an immunocompetent German male patient without travel history to Asia.
C. Pichler, M. Büchsel, J.W. Rossen, M. Vavra, S. Reuter, W.V. Kern, R. Thimme, A. Mischnik   +7 more
doaj   +1 more source

Hypervirulent Klebsiella pneumoniae K1 Liver Abscess. [PDF]

Intern Med
Homma Y, Yanagihara E, Harada S.
europepmc   +3 more sources

Sputum Gram stain of hypervirulent Klebsiella pneumoniae

Journal of General and Family Medicine, 2023
Hypervirulent Klebsiella pneumoniae has virulence genes relevant to capsule overproduction, which could lead to the finding of thick transparent area ("halo") in Gram stain. In sputum Gram stain, observation of a large Gram-negative rod with a thick capsule may not only indicate that it is K. pneumoniae but also that it is a highly virulent strain.
Yuji Nishihara, Takahito Nakamura, Yuki Suzuki, Kei Kasahara   +3 more
openaire   +3 more sources

Effects of gallic acid on capsular polysaccharide biosynthesis in Klebsiella pneumoniae

Journal of Microbiology, Immunology and Infection, 2022
Background: Klebsiella pneumoniae is a gram-negative opportunistic pathogen that causes diseases mostly in immunocompromised individuals. Recently, hypervirulent K. pneumoniae strains also cause severe disease in healthy individuals.
Tien-Huang Lin, Chien-Chen Wu, Cheng-Yin Tseng, Jing-Han Fang, Ching-Ting Lin   +4 more
doaj   +1 more source