Results 21 to 30 of about 4,827 (166)

Activity and specificity of a mouse monoclonal antibody to ferric aerobactin [PDF]

Infection and Immunity, 1992
We isolated a monoclonal antibody directed against the ferric complex of aerobactin purified from Escherichia coli KH576. This antibody, which we designated MAb AERO1, was identified as an immunoglobulin G, subtype 2. A competitive enzyme-linked immunosorbent assay with MAb AERO1 had a limit of 10 nM for the detection of purified ferric aerobactin and ...
D, le Roy, D, Expert, A, Razafindratsita, A, Deroussent, J, Cosme, C, Bohuon, A, Andremont   +6 more
openaire   +2 more sources

Genomic insights into virulence factors affecting tissue-invasive Klebsiella pneumoniae infection

Annals of Clinical Microbiology and Antimicrobials, 2022
Background The key virulence factors responsible for hypervirulent Klebsiella pneumoniae (hvKp) infection remains elusive. Methods We analyzed K. pneumoniae isolates collected between 2017 and 2019 and defined hvKp as a pyogenic infection.
Takashi Matono, Masatomo Morita, Nodoka Nakao, Yuji Teshima, Makoto Ohnishi   +4 more
doaj   +1 more source

ShiF acts as an auxiliary factor of aerobactin secretion in meningitis Escherichia coli strain S88

BMC Microbiology, 2019
Background The neonatal meningitis E. coli (NMEC) strain S88 carries a ColV plasmid named pS88 which is involved in meningeal virulence. Transcriptional analysis of pS88 in human serum revealed a strong upregulation of an ORF of unknown function: shiF ...
Mathieu Genuini, Philippe Bidet, Jean-François Benoist, Dimitri Schlemmer, Chloé Lemaitre, André Birgy, Stéphane Bonacorsi   +6 more
doaj   +1 more source

Aerobactin synthesis genes iucA and iucC contribute to the pathogenicity of avian pathogenic Escherichia coli O2 strain E058. [PDF]

PLoS ONE, 2013
Aerobactin genes are known to be present in virulent strains and absent from avirulent strains, but contributions of iucC and iucA, which are involved in aerobactin synthesis, to the pathogenicity of avian pathogenic Escherichia coli (APEC) have not been
Jielu Ling, Haizhu Pan, Qingqing Gao, Liping Xiong, Yefei Zhou, Debao Zhang, Song Gao, Xiufan Liu   +7 more
doaj   +1 more source

Analysis of Plasmids of the Klebsiella pneumoniae Complex Carrying a Cluster of Aerobactin Synthesis Genes as Presented in International Databases

Антибиотики и Химиотерапия, 2023
Background. Currently, it is customary to distinguish two pathotypes of Klebsiella pneumoniae — classical and hypervirulent, which have the ability to cause community-acquired infections in healthy people.
V. V. Shapovalova, Р. S. Chulkova, V. A. Ageevets   +2 more
doaj   +1 more source

Cloning of the aerobactin-mediated iron assimilation system of plasmid ColV [PDF]

Journal of Bacteriology, 1983
The high-affinity iron assimilation system of plasmid ColV-K30 was cloned on the vector plasmid pPlac. Plasmid pABN1 was isolated by means of sensitivity to cloacin, a bacteriocin using the same outer membrane receptor as ferric aerobactin. Restriction maps were determined for this plasmid and for a subclone, pABN5. Plasmid pABN1 codes for the complete
A, Bindereif, J B, Neilands
openaire   +2 more sources

Hypermucoviscosity, rmpA, and aerobactin are associated with community-acquired Klebsiella pneumoniae bacteremic isolates causing liver abscess in Singapore

Journal of Microbiology, Immunology and Infection, 2019
Introduction: This retrospective study investigated the clinical etiology of community-acquired bacteremic Klebsiella pneumoniae infections, and characterized laboratory and genetic markers which may be associated with primary liver abscess (PLA ...
Thean Yen Tan, Melissa Ong, Yvonne Cheng, Lily Siew Yong Ng   +3 more
doaj   +1 more source

Proline-rich antimicrobial peptide Api137 is bactericidal in porcine blood infected ex vivo with a porcine or human Klebsiella pneumoniae strain

Journal of Global Antimicrobial Resistance, 2021
Objectives: Klebsiella pneumoniae is an emerging invasive pathogen in humans and pigs. Resistance against multiple antibiotics in this species is a major health concern and the development of new antibiotics is urgently needed.
Ann-Kathrin Krieger, Daniel Knappe, Sophie Öhlmann, Leonie Mayer, Ines B. Eder, Gábor Köller, Ralf Hoffmann, Karoline Rieckmann, Christoph Georg Baums   +8 more
doaj   +1 more source

Aerobactin production and plasmid distribution in Escherichia coli clinical isolates [PDF]

FEMS Microbiology Letters, 1989
The distribution of plasmids as a function of aerobactin production, antibiotic resistance and antimicrobial agents production was studied in 139 Escherichia coli strains obtained from clinical sources. Ninety eight per cent of the strains analyzed presented plasmids with a median value of 2.97 plasmids per cell.
J L, Martínez, E, Cercenado, F, Baquero
openaire   +2 more sources

Analysis of the aerobactin and ferric hydroxamate uptake systems of Yersinia pestis [PDF]

Microbiology, 2007
Yersinia pestis genomes contain genes homologous to the aerobactin receptor (iutA) and biosynthetic genes (iucABCD) as well as the ferric hydroxamate uptake system (fhuCDB) of Escherichia coli. However, iucA is disrupted by a frameshift mutation. An E. coli strain carrying the cloned Y.
Stanislav, Forman, Michal J, Nagiec, Jennifer, Abney, Robert D, Perry, Jacqueline D, Fetherston   +4 more
openaire   +2 more sources