Results 1 to 10 of about 4,765 (201)

A global perspective on the convergence of hypervirulence and carbapenem resistance in Klebsiella pneumoniae

Journal of Global Antimicrobial Resistance, 2021
Hypervirulence and carbapenem resistance have emerged as two distinct evolutionary directions for Klebsiella pneumoniae, which pose a great threat in clinical settings.
Peng Lan, Yan Jiang, Jiancang Zhou, Yunsong Yu   +3 more
doaj   +2 more sources

The epidemiology and clinical characteristics of carbapenem-resistant Enterobacteriaceae (CRE) isolates from children in eastern China [PDF]

Frontiers in Microbiology
IntroductionCarbapenem-resistant Enterobacteriaceae (CRE) is the most common clinical pathogens. Investigating the antimicrobial resistance, hypervirulence and clinical characteristics of CRE isolated from children is helpful to guide for anti-infection ...
Yihan Zheng, Peng Mo, Dan Li, Lin Zhang, Yuqing Wang, Canhong Zhu, Yongdong Yan, Chuangli Hao, Xuejun Shao, Yang Li, Zhengrong Chen   +10 more
doaj   +2 more sources

Analysis of virulence profiles in clinical isolates of Klebsiella pneumoniae from renal abscesses: clinical significance of hypervirulent isolates

Frontiers in Cellular and Infection Microbiology
IntroductionKlebsiella pneumoniae can cause a wide range of infections. Hypervirulent K. pneumoniae (hvKp), particularly associated with the K1 and K2 capsular types, is an increasingly significant microorganism with the potential to cause invasive ...
Jaehyeon Lee, Jaehyeon Lee, Jeong-Hwan Hwang, Jeong-Hwan Hwang, Ji Hyun Yeom, Ji Hyun Yeom, Sik Lee, Sik Lee, Joo-Hee Hwang, Joo-Hee Hwang   +9 more
doaj   +1 more source

Transcriptomic Analysis Reveals Molecular Mechanisms Underpinning Mycovirus-Mediated Hypervirulence in Beauveria bassiana Infecting Tenebrio molitor

Journal of Fungi
Mycoviral infection can either be asymptomatic or have marked effects on fungal hosts, influencing them either positively or negatively. To fully understand the effects of mycovirus infection on the fungal host, transcriptomic profiling of four Beauveria
Charalampos Filippou, Robert H. A. Coutts, Ioly Kotta-Loizou, Sam El-Kamand, Alexie Papanicolaou   +4 more
doaj   +1 more source

Prevalence and features of hypervirulent Klebsiella pneumoniae in respiratory specimens at a US hospital system

Infection and Immunity
Hypervirulent Klebsiella pneumoniae (hvKp) strains are considered to be relatively rare in the United States, but cases are increasingly reported. We prospectively and serially collected K. pneumoniae clinical isolates identified in respiratory specimens
Christi L. McElheny, Alina Iovleva, Nathalie Chen, Dominic Woods, Akansha Pradhan, Jonah L. Sonnabend, Aidan R. Matunis, Nathan J. Raabe, Janet S. Lee, Giraldina Trevejo-Nuñez, Daria Van Tyne, Yohei Doi   +11 more
doaj   +1 more source

The hypervirulent Type-1/Type-17 phenotype of Cryptococcus neoformans clinical isolates is specific to A/J mice

Infection and Immunity
Cryptococcus neoformans is a fungal pathogen that causes cryptococcal meningitis in immunocompromised individuals. Both host- and pathogen-specific factors are known to affect patient outcome, and recent studies showed that strain-specific differences in
Minna Ding, Katrina M. Jackson, Madeline Harris-Gordon, Thamotharampillai Dileepan, David B. Meya, Kirsten Nielsen   +5 more
doaj   +1 more source

Genomic analyses identify nosocomial transmission of ST23 carbapenem-resistant hypervirulent Klebsiella pneumoniae mediated by a conjugative IncFIIK2 NDM-1 plasmid

Virulence
The World Health Organization has identified ST23 carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) as a critical public health threat.
Tao Chen, Xueting Wang, Luying Xiong, Yan Geng, Hui Ding, Yunbo Chen, Ping Shen, Yonghong Xiao   +7 more
doaj   +1 more source

Emergence of KPC-2 and NDM-13-coproducing carbapenem-resistant hypervirulent Klebsiella pneumoniae with high-risk sequence type ST11

Frontiers in Microbiology
BackgroundCarbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKp) co-producing KPC and NDM poses serious threats to public health. This study aimed to elucidate the molecular mechanisms underlying the resistance and virulence of a clinical CR ...
Jia Tao, Jia Tao, Liru Wang, Liru Wang, Na Yang, Hui Fu, Hui Fu, Xinxin Hu, Xinxin Hu, Tingyu Lai, Jianning Jin, Gang Li, Gang Li   +12 more
doaj   +1 more source

Clinical and Microbiological Characteristics of Klebsiella pneumoniae Bloodstream Infection in a Chinese Hospital: Hypervirulent and Multiclonal

Infection and Drug Resistance, 2022
Zike Sheng,1,* Junjie Li,2,* Tingting Chen,3 Yan Zhu,4 Xueping Yu,5 Xiuhua He,5 Yijuan Zheng,5 Cuiping Ma,6 Minghui Zheng,5 Peiyun Wang,1 Ziqiang Li,1 Yumin Xu,7 Qing Xie,1 Zhijun Su,5 Sumei Chen5 1Department of Infectious Diseases, Ruijin ...
Sheng Z, Li J, Chen T, Zhu Y, Yu X, He X, Zheng Y, Ma C, Zheng M, Wang P, Li Z, Xu Y, Xie Q, Su Z, Chen S   +14 more
doaj  

Report of a Fatal Purulent Pericarditis Case Caused by ST11-K64 Carbapenem-Resistant Hypervirulent Klebsiella pneumoniae

Infection and Drug Resistance, 2022
Shiwei Liang,1,2,* Huijun Cao,1,* Fei Ying,1 Chenchen Zhang2 1Centre for Clinical Laboratories, the Affiliated Hospital of Guizhou Medical University, Guiyang, People’s Republic of China; 2School of Clinical Laboratory Science, Guizhou Medical ...
Liang S, Cao H, Ying F, Zhang C
doaj