Results 1 to 10 of about 5,988 (207)

Prevalence of multidrug-resistant hypervirulent Klebsiella pneumoniae without defined hypervirulent biomarkers in Anhui, China: a new dimension of hypervirulence

open access: yesFrontiers in Microbiology, 2023
Klebsiella pneumoniae is an opportunistic pathogen that mainly causes nosocomial infections and hospital-associated pneumonia in elderly and immunocompromised people. However, multidrug-resistant hypervirulent K.
Md Roushan Ali, Zhien He
exaly   +5 more sources

A global perspective on the convergence of hypervirulence and carbapenem resistance in Klebsiella pneumoniae

open access: yesJournal of Global Antimicrobial Resistance, 2021
Hypervirulence and carbapenem resistance have emerged as two distinct evolutionary directions for Klebsiella pneumoniae, which pose a great threat in clinical settings.
Yan Jiang, Yunsong Yu
exaly   +3 more sources

Identification, Molecular Characterization, and Biology of a Novel Quadrivirus Infecting the Phytopathogenic Fungus Leptosphaeria biglobosa [PDF]

open access: yesViruses, 2018
Here we report the molecular characterisation of a novel dsRNA virus isolated from the filamentous, plant pathogenic fungus Leptosphaeria biglobosa and known to cause significant alterations to fungal pigmentation and growth and to result in ...
Unnati A. Shah   +3 more
doaj   +4 more sources

The case for hypervirulence through gene deletion in Mycobacterium tuberculosis

open access: yesTrends in Microbiology, 2008
Deletion of genes in a pathogen is commonly associated with a reduction in its ability to cause disease. However, some rare cases have been described in the literature whereby deletion of a gene results in an increase in virulence.
Farahnaz Movahedzadeh   +2 more
exaly   +2 more sources

Susceptibility of hamsters to clostridium difficile isolates of differing toxinotype [PDF]

open access: yes, 2013
Clostridium difficile is the most commonly associated cause of antibiotic associated disease (AAD), which caused ~21,000 cases of AAD in 2011 in the U.K. alone.
A Buckley   +53 more
core   +25 more sources

Ceftazidime-avibactam based combinations against carbapenemase producing Klebsiella pneumoniae harboring hypervirulence plasmids

open access: yesComputational and Structural Biotechnology Journal, 2022
The combination of carbapenem resistance and hypervirulence in Klebsiella pneumoniae is an emerging and urgent threat due to its potential to resist common antibiotics and cause life-threatening infections in healthy hosts.
Zackery P. Bulman   +9 more
doaj   +1 more source

Epidemiological characteristics and molecular evolution mechanisms of carbapenem-resistant hypervirulent Klebsiella pneumoniae

open access: yesFrontiers in Microbiology, 2022
Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP), a type of Klebsiella pneumoniae (KP) that exhibits hypervirulence and carbapenem resistance phenotypes, can cause severe infections, both hospital- and community-acquired infections.
Yu-Ling Han   +10 more
doaj   +1 more source

Convergence of multiple resistance and hypervirulence in Klebsiella pneumoniae

open access: yesИнфекция и иммунитет, 2022
Since 2018, Klebsiella pneumoniae isolates have been described in Russia, demonstrating the convergence of hypervirulent properties and multiple antibiotic resistance.
Vladimir A. Ageevets   +2 more
doaj   +1 more source

Hypercapsule is the cornerstone of Klebsiella pneumoniae in inducing pyogenic liver abscess

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
PurposeTo investigate the mechanisms of Klebsiella pneumoniae-induced pyogenic liver abscess (PLA).MethodsForty-three K. pneumoniae strains from PLAs and 436 from non-PLAs were collected.
Dakang Hu   +9 more
doaj   +1 more source

Deciphering the Epidemiological Characteristics and Molecular Features of blaKPC–2- or blaNDM–1-Positive Klebsiella pneumoniae Isolates in a Newly Established Hospital

open access: yesFrontiers in Microbiology, 2021
The emergence of hypervirulent carbapenem-resistant Klebsiella pneumoniae (hv-CRKP) was regarded as an emerging threat in clinical settings. Here, we investigated the prevalence of CRKP strains among inpatients in a new hospital over 1 year since its ...
Ruifei Chen   +8 more
doaj   +1 more source

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