Results 1 to 10 of about 3,631 (112)

Convergence of carbapenem resistance and hypervirulence in a highly-transmissible ST11 clone of K. pneumoniae: An epidemiological, genomic and functional study

Virulence, 2021
Co-occurrence of hypervirulence and KPC-2 carbapenem resistant phenotypes in a highly-transmissible ST11 clone ofKlebsiella pneumoniae has elicited deep concerns from public health stand point.
Youjun Feng, Man Huang, Beiwen Zheng
exaly   +2 more sources

Evaluation and analysis of multidrug resistance- and hypervirulence-associated genes in carbapenem-resistant Pseudomonas aeruginosa strains among children in an area of China for five consecutive years

Frontiers in Microbiology, 2023
IntroductionCarbapenem-resistant Pseudomonas aeruginosa (CRPA) is a growing threat. It is urgent to investigate the multidrug resistance and high virulence of CRPA to provide a basis for infection control and rational use of antibiotics.MethodsA ...
Xin Zhang, Xin Zhang, Xin Zhang, Yunfen Zhu, Yuanyuan Gao, Wei Li, Yunzhong Wang, Yunzhong Wang, Yang Li, Yang Li, Yang Li   +10 more
exaly   +3 more sources

Coexistence of carbapenemase and hypervirulence-associated genes among Klebsiella pneumoniae high-risk clones in Hungary [PDF]

Frontiers in Microbiology
IntroductionStrains of Klebsiella pneumoniae carrying hypervirulence and carbapenemase genes represent a rapidly emerging global public health threat.
Lilla Buzgó, Lilla Buzgó, Csongor Freytag, Dániel Göbhardter, Levente Laczkó, Levente Laczkó, László Miló, László Miló, Leila Holub, Adrienn Hanczvikkel, Erika Ungvári, László Majoros, Katalin Kamotsay, Katalin Papp, Katalin Kristóf, Gábor Kardos, Gábor Kardos, Ákos Tóth   +17 more
doaj   +2 more sources

Characteristics of Hypervirulent Klebsiella pneumoniae: Does Low Expression of rmpA Contribute to the Absence of Hypervirulence?

Frontiers in Microbiology, 2020
Multidrug-resistant hypervirulent Klebsiella pneumoniae (MDR-hvKP) has been increasingly reported and is now recognized as a significant threat to public health; however, characterization of MDR-hvKP has not been systematically investigated.
Zhi-wei Lin, Zhi-wei Lin, Jin-xin Zheng, Jin-xin Zheng, Bing Bai, Guang-jian Xu, Fo-jun Lin, Zhong Chen, Zhong Chen, Xiang Sun, Di Qu, Zhi-jian Yu, Qi-wen Deng   +12 more
exaly   +3 more sources

Prevalence of multidrug-resistant hypervirulent Klebsiella pneumoniae without defined hypervirulent biomarkers in Anhui, China: a new dimension of hypervirulence

Frontiers in Microbiology, 2023
Klebsiella pneumoniae is an opportunistic pathogen that mainly causes nosocomial infections and hospital-associated pneumonia in elderly and immunocompromised people. However, multidrug-resistant hypervirulent K.
Baolin Sun, Yujie Li, Zhien He
exaly   +3 more sources

The epidemiology and clinical characteristics of carbapenem-resistant Enterobacteriaceae (CRE) isolates from children in eastern China [PDF]

Frontiers in Microbiology
IntroductionCarbapenem-resistant Enterobacteriaceae (CRE) is the most common clinical pathogens. Investigating the antimicrobial resistance, hypervirulence and clinical characteristics of CRE isolated from children is helpful to guide for anti-infection ...
Yihan Zheng, Peng Mo, Dan Li, Lin Zhang, Yuqing Wang, Canhong Zhu, Yongdong Yan, Chuangli Hao, Xuejun Shao, Yang Li, Zhengrong Chen   +10 more
doaj   +2 more sources

Hypervirulence-associated pseudo-compound transposons as fundamental mobile units driving cross-species virulence dissemination in Enterobacteriaceae. [PDF]

PLoS Pathogens
BackgroundThe rapid global spread of hypervirulence in Enterobacteriaceae, particularly in carbapenem-resistant Klebsiella pneumoniae, poses a significant public health threat.
Shuaihua Fan, Lijun Wang, Chao Liu, Haoran Li, Huaiqing Qi, Pengcheng Du, Jun Guo   +6 more
doaj   +2 more sources

Global dissemination of conjugative virulence plasmids co-harboring hypervirulence and multidrug resistance genes in Klebsiella pneumoniae

MSystems
Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKp) has led to a high mortality rate in the clinical setting and garnered significant attention in the clinical and scientific communities.
Qi Xu, Chen Yang, Rong Zhang
exaly   +3 more sources

Ceftazidime-avibactam based combinations against carbapenemase producing Klebsiella pneumoniae harboring hypervirulence plasmids

Computational and Structural Biotechnology Journal, 2022
The combination of carbapenem resistance and hypervirulence in Klebsiella pneumoniae is an emerging and urgent threat due to its potential to resist common antibiotics and cause life-threatening infections in healthy hosts.
Zackery P. Bulman, Xing Tan, Ting-Yu Chu, Yanqin Huang, Amisha P. Rana, Nidhi Singh, Stephanie A. Flowers, Yasuhiro Kyono, Barry N. Kreiswirth, Liang Chen   +9 more
doaj   +1 more source

Epidemiological characteristics and molecular evolution mechanisms of carbapenem-resistant hypervirulent Klebsiella pneumoniae

Frontiers in Microbiology, 2022
Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP), a type of Klebsiella pneumoniae (KP) that exhibits hypervirulence and carbapenem resistance phenotypes, can cause severe infections, both hospital- and community-acquired infections.
Yu-Ling Han, Yu-Ling Han, Xu-Hui Wen, Xu-Hui Wen, Wen Zhao, Xi-Shan Cao, Jian-Xun Wen, Jun-Rui Wang, Zhi-De Hu, Wen-Qi Zheng, Wen-Qi Zheng   +10 more
doaj   +1 more source