Results 1 to 10 of about 3,415 (115)

Convergence of carbapenem resistance and hypervirulence in a highly-transmissible ST11 clone of K. pneumoniae: An epidemiological, genomic and functional study

Virulence, 2021
Co-occurrence of hypervirulence and KPC-2 carbapenem resistant phenotypes in a highly-transmissible ST11 clone ofKlebsiella pneumoniae has elicited deep concerns from public health stand point.
Beiwen Zheng, Lizhang Liu, Zhijiang Xu   +2 more
exaly   +2 more sources

A global perspective on the convergence of hypervirulence and carbapenem resistance in Klebsiella pneumoniae

Journal of Global Antimicrobial Resistance, 2021
Hypervirulence and carbapenem resistance have emerged as two distinct evolutionary directions for Klebsiella pneumoniae, which pose a great threat in clinical settings.
Yan Jiang, Yunsong Yu
exaly   +3 more sources

The epidemiology and clinical characteristics of carbapenem-resistant Enterobacteriaceae (CRE) isolates from children in eastern China [PDF]

Frontiers in Microbiology
IntroductionCarbapenem-resistant Enterobacteriaceae (CRE) is the most common clinical pathogens. Investigating the antimicrobial resistance, hypervirulence and clinical characteristics of CRE isolated from children is helpful to guide for anti-infection ...
Yihan Zheng, Peng Mo, Dan Li, Lin Zhang, Yuqing Wang, Canhong Zhu, Yongdong Yan, Chuangli Hao, Xuejun Shao, Yang Li, Zhengrong Chen   +10 more
doaj   +2 more sources

Prevalence of multidrug-resistant hypervirulent Klebsiella pneumoniae without defined hypervirulent biomarkers in Anhui, China: a new dimension of hypervirulence

Frontiers in Microbiology, 2023
Klebsiella pneumoniae is an opportunistic pathogen that mainly causes nosocomial infections and hospital-associated pneumonia in elderly and immunocompromised people. However, multidrug-resistant hypervirulent K.
Yuanyuan Dai, Huaiwei Lu, Zhien He
exaly   +3 more sources

Mortality risk of carbapenem-resistant hypervirulent Klebsiella pneumoniae vs. classical CR-KP: a systematic review and meta-analysis [PDF]

Frontiers in Public Health
BackgroundCarbapenem-resistant Klebsiella pneumoniae (K. pneumoniae, CR-KP) and hypervirulent K. pneumoniae (hvKP) represent two major clinical threats, due to high antimicrobial resistance and enhanced pathogenicity, respectively.
Jialiang Chen, Yue Hou, Jingang Shi, Xiaoyi Gao, Guowei Liang   +4 more
doaj   +2 more sources

Ceftazidime-avibactam based combinations against carbapenemase producing Klebsiella pneumoniae harboring hypervirulence plasmids

Computational and Structural Biotechnology Journal, 2022
The combination of carbapenem resistance and hypervirulence in Klebsiella pneumoniae is an emerging and urgent threat due to its potential to resist common antibiotics and cause life-threatening infections in healthy hosts.
Zackery P. Bulman, Xing Tan, Ting-Yu Chu, Yanqin Huang, Amisha P. Rana, Nidhi Singh, Stephanie A. Flowers, Yasuhiro Kyono, Barry N. Kreiswirth, Liang Chen   +9 more
doaj   +1 more source

Epidemiological characteristics and molecular evolution mechanisms of carbapenem-resistant hypervirulent Klebsiella pneumoniae

Frontiers in Microbiology, 2022
Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP), a type of Klebsiella pneumoniae (KP) that exhibits hypervirulence and carbapenem resistance phenotypes, can cause severe infections, both hospital- and community-acquired infections.
Yu-Ling Han, Yu-Ling Han, Xu-Hui Wen, Xu-Hui Wen, Wen Zhao, Xi-Shan Cao, Jian-Xun Wen, Jun-Rui Wang, Zhi-De Hu, Wen-Qi Zheng, Wen-Qi Zheng   +10 more
doaj   +1 more source

Convergence of multiple resistance and hypervirulence in Klebsiella pneumoniae

Инфекция и иммунитет, 2022
Since 2018, Klebsiella pneumoniae isolates have been described in Russia, demonstrating the convergence of hypervirulent properties and multiple antibiotic resistance.
Vladimir A. Ageevets, I. V. Ageevets, S. V. Sidorenko   +2 more
doaj   +1 more source

Hypercapsule is the cornerstone of Klebsiella pneumoniae in inducing pyogenic liver abscess

Frontiers in Cellular and Infection Microbiology, 2023
PurposeTo investigate the mechanisms of Klebsiella pneumoniae-induced pyogenic liver abscess (PLA).MethodsForty-three K. pneumoniae strains from PLAs and 436 from non-PLAs were collected.
Dakang Hu, Wenjie Chen, Weiwen Wang, Dongxing Tian, Pan Fu, Pan Fu, Ping Ren, Qing Mu, Gang Li, Xiaofei Jiang   +9 more
doaj   +1 more source

Deciphering the Epidemiological Characteristics and Molecular Features of blaKPC–2- or blaNDM–1-Positive Klebsiella pneumoniae Isolates in a Newly Established Hospital

Frontiers in Microbiology, 2021
The emergence of hypervirulent carbapenem-resistant Klebsiella pneumoniae (hv-CRKP) was regarded as an emerging threat in clinical settings. Here, we investigated the prevalence of CRKP strains among inpatients in a new hospital over 1 year since its ...
Ruifei Chen, Ziyi Liu, Ziyi Liu, Poshi Xu, Xinkun Qi, Shangshang Qin, Zhiqiang Wang, Ruichao Li, Ruichao Li   +8 more
doaj   +1 more source