Prevalence of Multidrug-Resistant Hypervirulent Klebsiella pneumoniae Without Defined Hypervirulent Biomarkers in Anhui, China: A New Dimension of Hypervirulence [PDF]
Klebsiella pneumoniae is an opportunistic pathogen that mainly causes nosocomial infections and hospital-associated pneumonia in elderly and immunocompromised people. However, multidrug-resistant hypervirulent K.
Baolin Sun, Md Roushan Ali, Zhien He
exaly +6 more sources
Hypervirulence-associated pseudo-compound transposons as fundamental mobile units driving cross-species virulence dissemination in Enterobacteriaceae. [PDF]
BackgroundThe rapid global spread of hypervirulence in Enterobacteriaceae, particularly in carbapenem-resistant Klebsiella pneumoniae, poses a significant public health threat.
Shuaihua Fan +6 more
doaj +3 more sources
Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKp) has led to a high mortality rate in the clinical setting and garnered significant attention in the clinical and scientific communities.
Qi Xu, Chen Yang, Rong Zhang
exaly +4 more sources
Molecular Insights Into Hypervirulent Klebsiella pneumoniae: Identification and Correlation of Virulence Determinant [PDF]
Klebsiella pneumoniae is an increasingly important opportunistic pathogen worldwide, particularly due to the emergence and spread of hypervirulent K. pneumoniae (hvKP), a clinically significant pathotype first identified in Taiwan.
Fathy M. Elkady +8 more
doaj +3 more sources
CRISPR/Cas diagnostics for Klebsiella pneumoniae: from resistance and hypervirulence markers to clinically interpretable risk reporting [PDF]
Klebsiella pneumoniae (Kp) is a major cause of healthcare-associated and community-onset invasive infections. The emergence of carbapenem-resistant Kp (CRKP), hypervirulent Kp (hvKp), and resistance–hypervirulence convergence has increased the need for ...
Weijia Yi +7 more
doaj +2 more sources
Co-occurrence of hypervirulence and KPC-2 carbapenem resistant phenotypes in a highly-transmissible ST11 clone ofKlebsiella pneumoniae has elicited deep concerns from public health stand point.
Youjun Feng, Man Huang, Beiwen Zheng
exaly +2 more sources
Convergence of Multiple Resistance and Hypervirulence in Klebsiella pneumoniae
Since 2018, Klebsiella pneumoniae isolates have been described in Russia, demonstrating the convergence of hypervirulent properties and multiple antibiotic resistance.
Vladimir Ageevets, Sergey Sidorenko
exaly +3 more sources
Identification of a hypervirulent extensively drug-resistant ST383 Klebsiella pneumoniae sub-lineage carrying ICEKp5 in Lebanon [PDF]
Klebsiella pneumoniae ST383 has emerged as a high-risk clone, characterized by carbapenem resistance and increasing detection of hypervirulence determinants. We describe a phylogenetically distinct ST383 sub-lineage in Lebanon, defined by the acquisition
Martine Abboud +15 more
doaj +2 more sources
Characteristics of Hypervirulent Klebsiella pneumoniae: Does Low Expression of rmpA Contribute to the Absence of Hypervirulence? [PDF]
Multidrug-resistant hypervirulent Klebsiella pneumoniae (MDR-hvKP) has been increasingly reported and is now recognized as a significant threat to public health; however, characterization of MDR-hvKP has not been systematically investigated.
Zhi-wei Lin +12 more
doaj +3 more sources
Differential Virulence by Strains of Cucumber mosaic virus is Mediated by the 2b Gene
The approximately 12-kDa 2b protein, encoded by all cucumoviruses, had been shown to play an important role in viral long-distance movement, hypervirulence, and suppression of post-transcriptional gene silencing.
Bu-Jun Shi +2 more
doaj +2 more sources

