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Hypervirulent Klebsiella pneumoniae
Hypervirulent Klebsiella pneumoniae (hvKP), especially multidrug-resistant hvKP (MDR-hvKP) infections, are distributed globally, and lead to several outbreaks with high pathogenicity and mortality in immunocompetent individuals. This is usually characterized by a rapidly metastatic spread resulting in multiple pyogenic tissue abscesses.
Junjun Chen, Huan Zhang, Xuelian Liao
openaire +5 more sources
Antimicrobial Resistance of Hypervirulent Klebsiella pneumoniae: Epidemiology, Hypervirulence-Associated Determinants, and Resistance Mechanisms [PDF]
Klebsiella pneumoniae is one of the most clinically relevant species in immunocompromised individuals responsible for community-acquired and nosocomial infections, including pneumonias, urinary tract infections, bacteremias, and liver abscesses. Since the mid-1980s, hypervirulent K. pneumoniae, generally associated with the hypermucoviscosity phenotype,
Chang-Ro Lee +7 more
openaire +4 more sources
The potential role of the bacterial persister formation gene <i>ptsH</i> in hypervirulence development in <i>Кlebsiella pneumoniae</i> [PDF]
Persistence – i.e., the ability to exist in a metabolically inactive form – allows bacteria to accumulate genetic advantages. The evolution of the pathogenic potential of Klebsiella pneumoniae has led to the emergence of strains simultaneously ...
A. V. Tutel'yan +8 more
core +2 more sources
The Occurence of Colistin-Resistant Hypervirulent Klebsiellapneumoniae in China [PDF]
Hypervirulent Klebsiella pneumoniae strains are usually susceptible to many antimicrobial agents including colistin. Here we report the isolation and characterization of several colistin-resistant hypervirulent K. pneumoniae clinical strains.
Yang Lu +9 more
doaj +3 more sources
Coexistence of carbapenemase and hypervirulence-associated genes among Klebsiella pneumoniae high-risk clones in Hungary [PDF]
IntroductionStrains of Klebsiella pneumoniae carrying hypervirulence and carbapenemase genes represent a rapidly emerging global public health threat.
Lilla Buzgó +17 more
doaj +2 more sources
The combination of carbapenem resistance and hypervirulence in Klebsiella pneumoniae is an emerging and urgent threat due to its potential to resist common antibiotics and cause life-threatening infections in healthy hosts.
Zackery P. Bulman +9 more
doaj +1 more source
Virulence Factors in Hypervirulent Klebsiella pneumoniae [PDF]
Hypervirulent Klebsiella pneumoniae (hvKP) has spread globally since first described in the Asian Pacific Rim. It is an invasive variant that differs from the classical K.
Jie Zhu +4 more
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Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP), a type of Klebsiella pneumoniae (KP) that exhibits hypervirulence and carbapenem resistance phenotypes, can cause severe infections, both hospital- and community-acquired infections.
Yu-Ling Han +10 more
doaj +1 more source
Hypervirulent Klebsiella pneumoniae [PDF]
Hypervirulent K. pneumoniae (hvKp) is an evolving pathotype that is more virulent than classical K. pneumoniae (cKp). hvKp usually infects individuals from the community, who are often healthy.
Thomas A, Russo, Candace M, Marr
openaire +2 more sources
IntroductionCarbapenem-resistant Pseudomonas aeruginosa (CRPA) is a growing threat. It is urgent to investigate the multidrug resistance and high virulence of CRPA to provide a basis for infection control and rational use of antibiotics.MethodsA ...
Xin Zhang +10 more
doaj +1 more source

