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Hypervirulent Klebsiella pneumoniae

open access: yesInfection and Drug Resistance, 2023
Hypervirulent Klebsiella pneumoniae (hvKP), especially multidrug-resistant hvKP (MDR-hvKP) infections, are distributed globally, and lead to several outbreaks with high pathogenicity and mortality in immunocompetent individuals. This is usually characterized by a rapidly metastatic spread resulting in multiple pyogenic tissue abscesses.
Junjun Chen, Huan Zhang, Xuelian Liao
openaire   +5 more sources

Antimicrobial Resistance of Hypervirulent Klebsiella pneumoniae: Epidemiology, Hypervirulence-Associated Determinants, and Resistance Mechanisms [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2017
Klebsiella pneumoniae is one of the most clinically relevant species in immunocompromised individuals responsible for community-acquired and nosocomial infections, including pneumonias, urinary tract infections, bacteremias, and liver abscesses. Since the mid-1980s, hypervirulent K. pneumoniae, generally associated with the hypermucoviscosity phenotype,
Chang-Ro Lee   +7 more
openaire   +4 more sources

The potential role of the bacterial persister formation gene <i>ptsH</i> in hypervirulence development in <i>Кlebsiella pneumoniae</i> [PDF]

open access: yesActa Naturae
Persistence – i.e., the ability to exist in a metabolically inactive form – allows bacteria to accumulate genetic advantages. The evolution of the pathogenic potential of Klebsiella pneumoniae has led to the emergence of strains simultaneously ...
A. V. Tutel'yan   +8 more
core   +2 more sources

The Occurence of Colistin-Resistant Hypervirulent Klebsiellapneumoniae in China [PDF]

open access: yesFrontiers in Microbiology, 2018
Hypervirulent Klebsiella pneumoniae strains are usually susceptible to many antimicrobial agents including colistin. Here we report the isolation and characterization of several colistin-resistant hypervirulent K. pneumoniae clinical strains.
Yang Lu   +9 more
doaj   +3 more sources

Coexistence of carbapenemase and hypervirulence-associated genes among Klebsiella pneumoniae high-risk clones in Hungary [PDF]

open access: yesFrontiers in Microbiology
IntroductionStrains of Klebsiella pneumoniae carrying hypervirulence and carbapenemase genes represent a rapidly emerging global public health threat.
Lilla Buzgó   +17 more
doaj   +2 more sources

Ceftazidime-avibactam based combinations against carbapenemase producing Klebsiella pneumoniae harboring hypervirulence plasmids

open access: yesComputational and Structural Biotechnology Journal, 2022
The combination of carbapenem resistance and hypervirulence in Klebsiella pneumoniae is an emerging and urgent threat due to its potential to resist common antibiotics and cause life-threatening infections in healthy hosts.
Zackery P. Bulman   +9 more
doaj   +1 more source

Virulence Factors in Hypervirulent Klebsiella pneumoniae [PDF]

open access: yesFrontiers in Microbiology, 2021
Hypervirulent Klebsiella pneumoniae (hvKP) has spread globally since first described in the Asian Pacific Rim. It is an invasive variant that differs from the classical K.
Jie Zhu   +4 more
openaire   +3 more sources

Epidemiological characteristics and molecular evolution mechanisms of carbapenem-resistant hypervirulent Klebsiella pneumoniae

open access: yesFrontiers in Microbiology, 2022
Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP), a type of Klebsiella pneumoniae (KP) that exhibits hypervirulence and carbapenem resistance phenotypes, can cause severe infections, both hospital- and community-acquired infections.
Yu-Ling Han   +10 more
doaj   +1 more source

Hypervirulent Klebsiella pneumoniae [PDF]

open access: yesClinical Microbiology Reviews, 2019
Hypervirulent K. pneumoniae (hvKp) is an evolving pathotype that is more virulent than classical K. pneumoniae (cKp). hvKp usually infects individuals from the community, who are often healthy.
Thomas A, Russo, Candace M, Marr
openaire   +2 more sources

Evaluation and analysis of multidrug resistance- and hypervirulence-associated genes in carbapenem-resistant Pseudomonas aeruginosa strains among children in an area of China for five consecutive years

open access: yesFrontiers in Microbiology, 2023
IntroductionCarbapenem-resistant Pseudomonas aeruginosa (CRPA) is a growing threat. It is urgent to investigate the multidrug resistance and high virulence of CRPA to provide a basis for infection control and rational use of antibiotics.MethodsA ...
Xin Zhang   +10 more
doaj   +1 more source

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