Results 21 to 30 of about 5,988 (207)

SpxA1 and SpxA2 act coordinately to fine-tune stress responses and virulence in Streptococcus pyogenes [PDF]

open access: yes, 2017
SpxA is a unique transcriptional regulator highly conserved among members of the phylum Firmicutes that binds RNA polymerase and can act as an antiactivator. Why some Firmicutes members have two highly similar SpxA paralogs is not understood.
Gary C. Port   +4 more
core   +7 more sources

Bloodstream Infections Caused by Klebsiella pneumoniae Carbapenemase–Producing P. aeruginosa Sequence Type 463, Associated With High Mortality Rates in China: A Retrospective Cohort Study

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
ObjectivesRecently, KPC-producing P. aeruginosa has rapidly emerged and expanded in East China. Here we described the clinical impact and characteristics of bloodstream infections (BSIs) from the dominant KPC-producing CRPA belonging to Sequence Type (ST)
Hangbin Hu   +14 more
doaj   +1 more source

Acquisition of the Conjugative Virulence Plasmid From a CG23 Hypervirulent Klebsiella pneumoniae Strain Enhances Bacterial Virulence

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
The emergence of hypervirulent and carbapenem-resistant Klebsiella pneumoniae (hv-CRKP) has become a hot topic and confounding problem for clinicians and researchers alike.
Dongxing Tian   +7 more
doaj   +1 more source

String test of hypervirulent Klebsiella pneumonia [PDF]

open access: yesQJM, 2014
A 63-year-old woman with a history of type 1 diabetes mellitus and IgA nephropathy, on maintenance dialysis for 10 years, presented with exertional dyspnea of 1 week’s duration and bloody sputum since the previous day. On the day of admission, the patient had awoken with clouding of consciousness; she was brought to the emergency outpatient department
A, Kumabe, T, Kenzaka
openaire   +2 more sources

Antimicrobial Resistance of Hypervirulent Klebsiella pneumoniae: Epidemiology, Hypervirulence-Associated Determinants, and Resistance Mechanisms [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2017
Klebsiella pneumoniae is one of the most clinically relevant species in immunocompromised individuals responsible for community-acquired and nosocomial infections, including pneumonias, urinary tract infections, bacteremias, and liver abscesses. Since the mid-1980s, hypervirulent K. pneumoniae, generally associated with the hypermucoviscosity phenotype,
Chang-Ro Lee   +7 more
openaire   +3 more sources

The making of hypervirulent Klebsiella pneumoniae

open access: yesJournal of Clinical Laboratory Analysis, 2022
AbstractKlebsiella pneumoniae is a notorious bacterium in clinical practice. Virulence, carbapenem‐resistance and their convergence among K. pneumoniae are extensively discussed in this article. Hypervirulent K. pneumoniae (HvKP) has spread from the Asian Pacific Rim to the world, inducing various invasive infections, such as pyogenic liver abscess ...
Piaopiao Dai, Dakang Hu
openaire   +2 more sources

Role of glucose and CcpA in capsule expression and virulence of Streptococcus suis [PDF]

open access: yes, 2011
Streptococcus suis is one of the most important pathogens in pigs and is also an emerging zoonotic agent. After crossing the epithelial barrier, S. suis causes bacteraemia, resulting in meningitis, endocarditis and bronchopneumonia.
A. de Greeff   +14 more
core   +10 more sources

Molecular Characterization of the Convergent Carbapenem-Resistant and Hypervirulent Klebsiella pneumoniae Strain K1-ST23, Collected in Chile during the COVID-19 Pandemic

open access: yesMicrobiology Spectrum, 2023
The aim of this study was to investigate the genomic features of a carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKp) isolate (K-2157) collected in Chile.
Felipe Morales-León   +10 more
doaj   +1 more source

Pathogenesis of Hypervirulent Group A Streptococcus [PDF]

open access: yesJapan Journal of Medicine, 2018
Group A Streptococcus (GAS) causes common pharyngitis and skin infections and occasional severe invasive infections. This review describes the recent progress on the pathogenesis of hypervirulent GAS. CovRS mutations are frequent among invasive GAS isolates and lead to hypervirulence. GAS CovRS mutants can be selected in vivo by neutrophils.
Mengyao, Liu, Benfang, Lei
openaire   +2 more sources

Hypervirulent carbapenem-resistant Klebsiella pneumoniae causing highly fatal meningitis in southeastern China

open access: yesFrontiers in Public Health, 2022
Klebsiella pneumoniae (K. pneumoniae) is one of the most common causes of bacterial meningitis worldwide. The purpose of this study was to investigate the clinical and microbiological characteristics of K.
Na Huang   +11 more
doaj   +1 more source

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