Results 21 to 30 of about 3,484 (175)

The making of hypervirulent Klebsiella pneumoniae

Journal of Clinical Laboratory Analysis, 2022
AbstractKlebsiella pneumoniae is a notorious bacterium in clinical practice. Virulence, carbapenem‐resistance and their convergence among K. pneumoniae are extensively discussed in this article. Hypervirulent K. pneumoniae (HvKP) has spread from the Asian Pacific Rim to the world, inducing various invasive infections, such as pyogenic liver abscess ...
Piaopiao Dai, Dakang Hu
openaire   +2 more sources

Bloodstream Infections Caused by Klebsiella pneumoniae Carbapenemase–Producing P. aeruginosa Sequence Type 463, Associated With High Mortality Rates in China: A Retrospective Cohort Study

Frontiers in Cellular and Infection Microbiology, 2021
ObjectivesRecently, KPC-producing P. aeruginosa has rapidly emerged and expanded in East China. Here we described the clinical impact and characteristics of bloodstream infections (BSIs) from the dominant KPC-producing CRPA belonging to Sequence Type (ST)
Hangbin Hu, Yan Zhang, Piaopiao Zhang, Jie Wang, Qing Yuan, Weixiao Shi, Sheng Zhang, Haiting Feng, Yunbo Chen, Meihong Yu, Hongchao Chen, Yan Jiang, Qing Yang, Tingting Qu, Tingting Qu   +14 more
doaj   +1 more source

Acquisition of the Conjugative Virulence Plasmid From a CG23 Hypervirulent Klebsiella pneumoniae Strain Enhances Bacterial Virulence

Frontiers in Cellular and Infection Microbiology, 2021
The emergence of hypervirulent and carbapenem-resistant Klebsiella pneumoniae (hv-CRKP) has become a hot topic and confounding problem for clinicians and researchers alike.
Dongxing Tian, Weiwen Wang, Meng Li, Wenjie Chen, Ying Zhou, Yunkun Huang, Zike Sheng, Xiaofei Jiang   +7 more
doaj   +1 more source

Molecular Characterization of the Convergent Carbapenem-Resistant and Hypervirulent Klebsiella pneumoniae Strain K1-ST23, Collected in Chile during the COVID-19 Pandemic

Microbiology Spectrum, 2023
The aim of this study was to investigate the genomic features of a carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKp) isolate (K-2157) collected in Chile.
Felipe Morales-León, Maximiliano Matus-Köhler, Pablo Araya-Vega, Felipe Aguilera, Ignacio Torres, Rodrigo Vera, Camila Ibarra, Sebastián Venegas, Helia Bello-Toledo, Gerardo González-Rocha, Andrés Opazo-Capurro   +10 more
doaj   +1 more source

Hypervirulent carbapenem-resistant Klebsiella pneumoniae causing highly fatal meningitis in southeastern China

Frontiers in Public Health, 2022
Klebsiella pneumoniae (K. pneumoniae) is one of the most common causes of bacterial meningitis worldwide. The purpose of this study was to investigate the clinical and microbiological characteristics of K.
Na Huang, Huaiyu Jia, Beibei Zhou, Cui Zhou, Jianming Cao, Wenli Liao, Shixing Liu, Lingbo Wang, Liqiong Chen, Lijiang Chen, Tieli Zhou, Jianzhong Ye   +11 more
doaj   +1 more source

Antimicrobial Resistance of Hypervirulent Klebsiella pneumoniae: Epidemiology, Hypervirulence-Associated Determinants, and Resistance Mechanisms [PDF]

Frontiers in Cellular and Infection Microbiology, 2017
Klebsiella pneumoniae is one of the most clinically relevant species in immunocompromised individuals responsible for community-acquired and nosocomial infections, including pneumonias, urinary tract infections, bacteremias, and liver abscesses. Since the mid-1980s, hypervirulent K. pneumoniae, generally associated with the hypermucoviscosity phenotype,
Chang-Ro Lee, Jung Hun Lee, Kwang Seung Park, Jeong Ho Jeon, Young Bae Kim, Chang-Jun Cha, Byeong Chul Jeong, Sang Hee Lee   +7 more
openaire   +3 more sources

Differential Virulence by Strains of Cucumber mosaic virus is Mediated by the 2b Gene

Molecular Plant-Microbe Interactions, 2002
The approximately 12-kDa 2b protein, encoded by all cucumoviruses, had been shown to play an important role in viral long-distance movement, hypervirulence, and suppression of post-transcriptional gene silencing.
Bu-Jun Shi, Peter Palukaitis, Robert H. Symons   +2 more
doaj   +1 more source

A Potential High-Risk Clone of Pseudomonas aeruginosa ST463

Frontiers in Microbiology, 2021
Pseudomonas aeruginosa is one of the most common opportunistic pathogens, which causes severe nosocomial infections because of its well-known multidrug-resistance and hypervirulence. It is critical to curate routinely the epidemic P.
Yanyan Hu, Wenjing Peng, Yifan Wu, Hui Li, Qi Wang, Huahua Yi, Rong Zhang, Bing Shao, Kui Zhu   +8 more
doaj   +1 more source

String test of hypervirulent Klebsiella pneumonia [PDF]

QJM, 2014
A 63-year-old woman with a history of type 1 diabetes mellitus and IgA nephropathy, on maintenance dialysis for 10 years, presented with exertional dyspnea of 1 week’s duration and bloody sputum since the previous day. On the day of admission, the patient had awoken with clouding of consciousness; she was brought to the emergency outpatient department
A, Kumabe, T, Kenzaka
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Evaluation and analysis of multidrug resistance- and hypervirulence-associated genes in carbapenem-resistant Pseudomonas aeruginosa strains among children in an area of China for five consecutive years

Frontiers in Microbiology, 2023
IntroductionCarbapenem-resistant Pseudomonas aeruginosa (CRPA) is a growing threat. It is urgent to investigate the multidrug resistance and high virulence of CRPA to provide a basis for infection control and rational use of antibiotics.MethodsA ...
Xin Zhang, Xin Zhang, Xin Zhang, Yunfen Zhu, Yuanyuan Gao, Wei Li, Yunzhong Wang, Yunzhong Wang, Yang Li, Yang Li, Yang Li   +10 more
doaj   +1 more source