Results 11 to 20 of about 4,827 (166)
The pathogenicity of or aerobactin-positive in infected mice [PDF]
Objectives To investigate the pathogenicity of Klebsiella pneumoniae (KPN) possessing rmpA or the aerobactin gene in infected mice. Methods BALB/c mice were divided into four groups (nā=ā10 per group) and infected with: string test-positive and rmpA ...
Guili Li +3 more
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Aerobactin genes in Shigella spp [PDF]
Aerobactin, a hydroxamate iron transport compound, is synthesized by some, but not all, Shigella species. Conjugation and hybridization studies indicated that the genes for the synthesis and transport of aerobactin are linked and are found on the chromosome of Shigella flexneri, S. boydii, and S. sonnei. The genes were not found in S. dysenteriae.
K M, Lawlor, S M, Payne
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Production of the siderophore aerobactin by a halophilic pseudomonad [PDF]
A bacterial strain, isolated from a cyanobacterial culture, was identified as Pseudomonas sp. strain X40. Under iron-limiting conditions, the Pseudomonas sp. produced aerobactin, a dihydroxamate siderophore previously found only in the family Enterobacteriaceae. Aerobactin was identified by electrophoretic mobility, spectrophotometric titration, proton
J S, Buyer, V, de Lorenzo, J B, Neilands
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BackgroundThe incidence of hypervirulent (hv) carbapenem-resistant (CR) Klebsiella pneumoniae (Kp) is increasing globally among various clones and is also responsible for nosocomial infections.
Chaitra Shankar +8 more
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Novel Aerobactin Receptor in Klebsiella pneumoniae [PDF]
Several Klebsiella pneumoniae strains which produced enterochelin but not aerobactin were nevertheless sensitive to cloacin DF13. In contrast, a strain of serotype K1:O1 which produced both siderophores was cloacin-resistant. Loss by mutation of the O1 but not K1 antigen rendered this strain cloacin-sensitive, indicating that the O1 antigen prevented ...
P, Williams +4 more
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Aerobactin genes in clinical isolates of Escherichia coli [PDF]
The location of the aerobactin gene complex on either the chromosome or plasmid was determined in eight aerobactin-positive clinical isolates of Escherichia coli by Southern hybridization analysis, using as probes the cloned aerobactin genes from the ColV-K30 plasmid.
A, Bindereif, J B, Neilands
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Biochemical genetics of aerobactin biosynthesis in Escherichia coli [PDF]
Single-gene mutants of Escherichia coli defective in aerobactin biosynthesis were incubated under non-growing conditions for 2 h with radiolabelled lysine. Analysis of the intermediates produced suggested that acetylation of lysine may be the first step in aerobactin production.
Steven Ford +2 more
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Production of aerobactin by some species of the genus Yersinia [PDF]
Seventy-seven isolates of Yersinia species were examined for evidence of hydroxamate biosynthesis. A total of 7 of 12 Y. frederiksenii, 1 of 5 Y. kristensenii, and 5 of 5 Y. intermedia isolates synthesized an hydroxamate species which was chromatographically and electrophoretically identical to aerobactin. Proof that this material was indeed aerobactin
S J, Stuart +2 more
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Multidrug-resistant hypervirulent Klebsiella pneumoniae (MDR-hvKP) has been increasingly reported and is now recognized as a significant threat to public health; however, characterization of MDR-hvKP has not been systematically investigated.
Zhi-wei Lin +12 more
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Subcloning of the cloacin DF13/aerobactin receptor protein and identification of a pColV-K30-determined polypeptide involved in ferric-aerobactin uptake [PDF]
A plasmid containing a pColV-K30 fragment that encoded only for the cloacin DF13/aerobactin receptor protein was constructed. Escherichia coli cells harboring this plasmid were sensitive to cloacin DF13 but were unable to take up ferric-aerobactin. Another pColV-K30-determined polypeptide (molecular weight, 50,000), localized in the membrane fraction ...
W J, Krone +4 more
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