Results 41 to 50 of about 5,820 (182)

Hypervirulent Klebsiella pneumoniae in a South African tertiary hospital—Clinical profile, genetic determinants, and virulence in Caenorhabditis elegans

Frontiers in Microbiology
IntroductionA distinct strain of Klebsiella pneumoniae (K. pneumoniae) referred to as hypervirulent (hvKp) is associated with invasive infections such as pyogenic liver abscess in young and healthy individuals.
Likhona Dingiswayo, Olusesan Adeyemi Adelabu, Emmanuel Arko-Cobbah, Carolina Pohl, Nthabiseng Zelda Mokoena, Morne Du Plessis, Jolly Musoke, Jolly Musoke   +7 more
doaj   +1 more source

In vivo bioluminescence imaging of Escherichia coli O104:H4 and role of aerobactin during colonization of a mouse model of infection

BMC Microbiology, 2012
Background A major outbreak of bloody diarrhea associated with Shiga toxin-producing Escherichia coli O104:H4 occurred early in 2011, to which an unusual number of hemolytic uremic syndrome cases were linked.
Torres Alfredo G, Cieza Roberto J, Rojas-Lopez Maricarmen, Blumentritt Carla A, Souza Cristiane S, Johnston R, Strockbine Nancy, Kaper James B, Sbrana Elena, Popov Vsevolod L   +9 more
doaj   +1 more source

The iucC gene is a major contributor to the virulence of hypervirulent Klebsiella pneumoniae

Frontiers in Cellular and Infection Microbiology
BackgroundHypervirulent Klebsiella pneumoniae (hvKp) is a critical pathogen that causes highly lethal invasive infections with its virulence linked to that of aerobactin, the core siderophore system of hvKp.MethodsHere, 20 porcine-derived K.
Chong Chen, Li Wang, Shuo Zu, Hui Ning, Liran Song, Jianbao Dong, Changjiang Sun, Xin Feng, Wenyu Han, Wenyu Han, Yalu Ji, Jingmin Gu, Jingmin Gu   +12 more
doaj   +1 more source

Exploring Cervical Cancer‐Associated Vaginal and Cervical Microbiota via 16S rRNA Sequencing

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
This 16S sequencing study identified a dysbiotic cervical microbiota (increased diversity, reduced Lactobacillus, enriched Prevotella) specifically linked to high‐risk HPV infection. These microbial alterations, shaped by the HPV‐driven microenvironment, offer novel targets for biomarkers and mechanistic research in cervical carcinogenesis.
Guojiao Wang, Xiaotong Liu, Zimo Wang, Huadong Tian, Yan Li, Yuexi Luo   +5 more
wiley   +1 more source

Highly conserved composite transposon harbouring aerobactin iuc3 in Klebsiella pneumoniae from pigs [PDF]

, 2023
Klebsiella pneumoniae is an important opportunistic pathogen associated with severe invasive disease in humans. Hypervirulent K. pneumoniae, which are K.
Kaspersen, Håkon, Jiwakanon, Jatesada, Hetland, Marit, Urdahl, Anne Margrete, Löhr, Iren Høyland, Leangapichart, Thongpan, Franklin-Alming, Fiona, Sunde, Marianne, Bernhoff, Eva   +8 more
core   +1 more source

Identification of Potential Vaccine Strains of Escherichia coli Isolates From Diarrhoeic Calves

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
This study aimed to identify vaccine candidate Escherichia coli strains isolated from diarrheic calves. Faecal samples collected from 500 calves were analysed, and E. coli strains were isolated and characterized phenotypically and genotypically. Antibiotic resistance profiles, virulence‐associated genes and MLVA genotyping were used to select 20 ...
Yasemin Erdoğan, Ediz Kağan Özgen, Murat Özmen, Elif Karadeniz Pütür, Nebahat Polat, Ersan Pütür, Mücahit Harmancı, Ercan Atalay, Ahmet Temur, Meryem Güloğlu, Lütfullah Celep, Seyda Cengiz, Mehmet Cemal Adıgüzel, Cihan Öz, Timur Gülhan, Alper Çiftci, Erhan Çiftgül   +16 more
wiley   +1 more source

Expression of aerobactin genes by Shigella flexneri during extracellular and intracellular growth [PDF]

Infection and Immunity, 1997
The expression of the Shigella flexneri chromosomal aerobactin genes during growth of the bacterium within tissue culture cells was assayed. During intracellular growth, aerobactin promoter activity was repressed relative to the level observed in bacteria grown extracellularly, even when the bacteria had been starved for iron prior to infection ...
V, Headley, M, Hong, M, Galko, S M, Payne   +3 more
openaire   +2 more sources

Emergence of Ceftazidime‐Avibactam‐Induced KPC Variants (KPC‐25/127) in Intracranial Infection and Implications for Clinical Management

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Novel KPC‐25 and first‐reported KPC‐127 sequentially evolved in one patient under CAZ‐AVI pressure, distinct mutations remodel enzyme activity to drive differential multidrug resistance. ABSTRACT The emergence of novel Klebsiella pneumoniae carbapenemase (KPC) variants contributing to clinical treatment failure poses a substantial threat to public ...
Ke Lei, Ying Tian, Chaoliang Xiong, Jing Lei, Dong Chen, Xiangni Bai, Mohd H. Abdul‐Aziz, Jiao Xie, Zeshi Liu   +8 more
wiley   +1 more source

The aerobactin iron uptake system of plasmid ColV-K30 in Escherichia coli.

, 1985
Some strains of Escherichia coli possess an iron uptake system, first found on a ColV plasmid, which utilises the hydroxamate siderophore aerobactin and which significantly enhances the virulence of host bacteria in experimental infections of mice.
Nicholas Henry. Carbonetti (7699745)
core   +6 more sources

Comparative genomic analysis and characterization of incompatibility group FIB plasmid encoded virulence factors of Salmonella enterica isolated from food sources

BMC Genomics, 2017
Background The degree to which the chromosomal mediated iron acquisition system contributes to virulence of many bacterial pathogens is well defined.
Bijay K. Khajanchi, Nur A. Hasan, Seon Young Choi, Jing Han, Shaohua Zhao, Rita R. Colwell, Carl E. Cerniglia, Steven L. Foley   +7 more
doaj   +1 more source