Results 61 to 70 of about 4,827 (166)

Prevalence of Hypervirulent rmpA and magA Genes in Clinical Isolates of Klebsiella pneumoniae and their association with Drug Resistant Pattern: A Cross-sectional Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Hypervirulent Klebsiella pneumoniae (hvKp) has emerged as a pathogen of global concern that is hypermucoviscous, causing infections and rapidly acquiring Antimicrobial Resistance (AMR). HvKp is more virulent than classical K.
Kanimozhi Devanathan, Umadevi Sivaraman, Rajkumar Chinnadurai, Joshy M Easow, Vickneshwaran Vinayagam   +4 more
doaj   +1 more source

Genomic and Pathogenic Characterization of an Extensively Drug‐Resistant Avian Pathogenic Escherichia coli Strain

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Extensively drug‐resistant (XDR) avian pathogenic Escherichia coli (APEC) poses a global threat to poultry and public health. In this study, we isolated an APEC strain, SDLYRA415, from broilers in Shandong, China, during an outbreak with ~20% mortality.
Weishi Ni, Lijuan Chen, Hao Chen, Kejing Wang, Lumin Yu, Xinglin Zhang, Peikun Wang, Ganwu Li   +7 more
wiley   +1 more source

The Siderophore Synthetase IucA of the Aerobactin Biosynthetic Pathway Uses an Ordered Mechanism

Biochemistry, 2020
Biosynthesis of the hydroxamate siderophore aerobactin requires the activity of four proteins encoded within the iuc operon. Recently, we biochemically reconstituted the biosynthetic pathway and structurally characterized IucA and IucC, two enzymes that sequentially couple N6-acetyl-N6-hydroxylysine to the primary carboxylates of citrate. IucA and IucC
Lisa S. Mydy, Daniel C. Bailey, Ketan D. Patel, Matthew R. Rice, Andrew M. Gulick   +4 more
openaire   +3 more sources

Evolutionary Origins and Virulence Determinants of ST25 Hypervirulent Klebsiella pneumoniae in Swine: Genomic Insights and Functional Validation

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The global spread of multidrug‐resistant hypervirulent Klebsiella pneumoniae (MDR‐HvKp), among which carbapenem‐resistant strains are of major concern, poses a severe threat to public health due to its high mortality rate and extremely limited treatment options.
Zheng Chen, Yang Liu, Congyang Du, Shengguo Gao, Lufeng Zhai, Stefan Schwarz, Weicheng Liu, Qiong Li, Longyu Li, Runhao Yu, Yuzhe Zhao, Hong Yao, Lei Luo, Xue Liu, Chunyan Xu, Xiang-Dang Du, Zongfu Wu   +16 more
wiley   +1 more source

Antibacterial and Osteogenic Applications of Ti‐Cu Alloys: A Review of Current Research and Future Directions

Advanced Materials Interfaces, Volume 12, Issue 23, December 8, 2025.
Given the growing interest in antibiotic‐free implant strategies and the need for biocompatible solutions to combat peri‐implantitis and implant failure, this review gives a timely and comprehensive overview of Ti‐Cu alloys as next‐generation biomaterials.
Brandon Fields, Elliot Makhani, Benjamin Makhani, Justin Cortez, Vivek Verma, Alexander Dupuy, Hamoun Sabri, Hom‐Lay Wang, Alexander Groetsch   +8 more
wiley   +1 more source

Frequency evaluation of genes encoding siderophores and the effects of different concentrations of Fe ions on growth rate of uropathogenic Escherichia coli

Iranian Journal of Microbiology, 2017
Background and Objectives: Bacteria need iron for growth and most of them can actively acquire Fe ions using especial iron-chelating proteins which named siderophores.
Behnoush khasheii, Shaghayegh Anvari, Ailar Jamalli   +2 more
doaj  

Phenotypic and Genotypic Profile of Enterobacteriaceae Isolated at a Teaching Hospital in Ghana

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
This study identified a significant prevalence of antimicrobial resistance determinants within Enterobacteriaceae isolates, with particular emphasis on those producing extended‐spectrum β‐lactamases (ESBL). These isolates harbored diverse antibiotic resistance genes (ARGs), plasmid replicons, and virulence factors (VFs), highlighting the imperative for
Bismark Donkor, Richael Odarkor Mills, Philimon Mwintige, Alberta Bedford Moses, Abigail Asmah Brown, Faustina Halm‐Lai, Oheneba Charles Kofi Hagan   +6 more
wiley   +1 more source

Virulence Factors and Antibiotic Resistance of Klebsiella pneumoniae Strains Isolated From Neonates With Sepsis

Frontiers in Medicine, 2018
Introduction:Klebsiella pneumoniae is one of the most important infectious agents in neonates. There are “classic” and hypervirulent strains of K. pneumoniae. The “classic” non-virulent strain of K. pneumoniae, producing extended-spectrum beta-lactamases
Khalit S. Khaertynov, Vladimir A. Anokhin, Albert A. Rizvanov, Yuriy N. Davidyuk, Dina R. Semyenova, Sergey A. Lubin, Natalia N. Skvortsova   +6 more
doaj   +1 more source

Metagenomic Profiling and Genome‐Centric Analysis Reveal Iron Acquisition Systems in Cheese‐Associated Bacteria and Fungi

Environmental Microbiology, Volume 27, Issue 12, December 2025.
This study describes the diversity of iron acquisition systems in cheese microorganisms and provides information on the distribution of siderophore biosynthesis pathways in both bacteria and fungi, including poorly characterised species. ABSTRACT Cheese microbial communities are composed of diverse interacting microorganisms, including both inoculated ...
Sibylle Tabuteau, Vincent Hervé, Françoise Irlinger, Christophe Monnet   +3 more
wiley   +1 more source

Molecular Typing of Klebsiella pneumoniae Clinical Isolates by Enterobacterial Repetitive Intergenic Consensus Polymerase Chain Reaction

International Journal of Microbiology, 2020
Aim. Klebsiella pneumoniae is one of the most important causes of nosocomial infections, including pneumonia, sepsis, and urinary tract infection. Enterobacterial repetitive intergenic consensus polymerase chain reaction (ERIC-PCR) technique is a quick ...
Parinaz Sedighi, Omid Zarei, Kiana Karimi, Mohammad Taheri, Pezhman Karami, Leili Shokoohizadeh   +5 more
doaj   +1 more source