Results 81 to 90 of about 5,820 (182)

Photoreactivity of Iron(III)−Aerobactin:  Photoproduct Structure and Iron(III) Coordination

, 2016
UV photolysis of the ferric aerobactin complex results in decarboxylation of the α-hydroxy carboxylic acid group of the central citrate moiety of aerobactin. The structure determination of the photooxidized ligand shows that decarboxylation occurs at the
Carl J. Carrano (1904941), Jens-Uwe Kuhn (2534470), Frithjof C. Küpper (142316), Alison Butler (469712)   +3 more
core   +1 more source

Genome sequence of the hypervirulent ST65 Klebsiella pneumoniae isolate carrying mcr-8 from China

Journal of Global Antimicrobial Resistance
Objective: In this study we report the complete genome sequence of a hypervirulent ST65 Klebsiella pneumoniae isolate harbouring mcr-8 from China. The aim was to investigate its molecular characteristics and resistance mechanisms.
Weili Zhang, Hao Xu, Yaling Li, Ruishan Liu, Danfeng Lou   +4 more
doaj   +1 more source

Molecular Typing of Klebsiella pneumoniae Clinical Isolates by Enterobacterial Repetitive Intergenic Consensus Polymerase Chain Reaction

International Journal of Microbiology, 2020
Aim. Klebsiella pneumoniae is one of the most important causes of nosocomial infections, including pneumonia, sepsis, and urinary tract infection. Enterobacterial repetitive intergenic consensus polymerase chain reaction (ERIC-PCR) technique is a quick ...
Parinaz Sedighi, Omid Zarei, Kiana Karimi, Mohammad Taheri, Pezhman Karami, Leili Shokoohizadeh   +5 more
doaj   +1 more source

Tracking key virulence loci encoding aerobactin and salmochelin siderophore synthesis in Klebsiella pneumoniae

Genome Medicine, 2018
Background Klebsiella pneumoniae is a recognised agent of multidrug-resistant (MDR) healthcare-associated infections; however, individual strains vary in their virulence potential due to the presence of mobile accessory genes.
Margaret M. C. Lam, Kelly L. Wyres, Louise M. Judd, Ryan R. Wick, Adam Jenney, Sylvain Brisse, Kathryn E. Holt   +6 more
doaj   +1 more source

The Frequency of Escherichia coli Strain Isolates Causing Urinary Tract Infections in the presence of Pathogenic Aerobactin Genes

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2015
BACKGROUND AND OBJECTIVE: Escherichia-coli is one of the major causes of urinary tract infection (UTI). The strains of this bacterium have a variety of virulence factors, such as iron acquisition systems, that provide the energy for iron transport ...
SM Mojabi, R Ranjbar
doaj  

Bio inspired microfluidic-based analysis of Klebsiella pneumoniae virulence factors and antimicrobial resistance

SLAS Technology
The objective of this research was to examine the antibiotic resistance and microbiological traits of Klebsiella pneumoniae isolates that were responsible for liver abscesses in Qingdao, China.
Xiaoping Song, Jun zhang, Weihong Hua, Yan Zheng, Xiaolin Liu, Yuanqi Zhu, Sun Bin, Jian Ding, Suling Sun   +8 more
doaj   +1 more source

Flanking and internal regions of chromosomal genes mediating aerobactin iron uptake systems in enteroinvasive Escherichia coli and Shigella flexneri

, 1987
We have investigated the presence of the aerobactin system and the location of the aerobactin genes in enteroinvasive strains of Escherichia coli.
Crosa, J H, Marolda, C L, Lawlor, K M, Valvano, M A; id_orcid, Payne, S M   +4 more
core   +2 more sources

Hypervirulent Klebsiella pneumoniae (hypermucoviscous and aerobactin positive) infection over 6 years in the elderly in China: antimicrobial resistance patterns, molecular epidemiology and risk factor

Annals of Clinical Microbiology and Antimicrobials, 2019
Background The definition of hypervirulent Klebsiella pneumoniae (hvKp), traditionally regarded as hypermucoviscosity, is controversial. However, data based on both phenotype (hypermucoviscous) and genetic (aerobactin) criteria are limited.
Chao Liu, Jun Guo
doaj   +1 more source

Deciphering the relative importance of genetic elements in hypervirulent Klebsiella pneumoniae to guide countermeasure developmentResearch in context

EBioMedicine
Summary: Background: Quantitating the contribution of phenotype-responsible elements in hypervirulent Klebsiella pneumoniae is needed. Methods: Isogenic mutants of four hypervirulent clinical isolates that produced K1 (ST23), K2 (ST86), K20 (ST1544), or
Thomas A. Russo, Ulrike Carlino-MacDonald, Zachary J. Drayer, Connor J. Davies, Cassandra L. Alvarado, Alan Hutson, Ting L. Luo, Melissa J. Martin, Patrick T. McGann, Francois Lebreton   +9 more
doaj   +1 more source

Occurrence of chromosome- or plasmid-mediated aerobactin iron transport systems and hemolysin production among clonal groups of human invasive strains of Escherichia coli K1

, 1986
The incidence of the aerobactin system and the genetic location of aerobactin genes were investigated in Escherichia coli K1 neonatal isolates belonging to different clonal groups. A functional aerobactin system was found in all members of the O7 MP3, O1
Crosa, J H, Silver, R P, Valvano, M A; id_orcid   +2 more
core   +2 more sources