Results 71 to 80 of about 4,827 (166)

Genome sequence of the hypervirulent ST65 Klebsiella pneumoniae isolate carrying mcr-8 from China

Journal of Global Antimicrobial Resistance
Objective: In this study we report the complete genome sequence of a hypervirulent ST65 Klebsiella pneumoniae isolate harbouring mcr-8 from China. The aim was to investigate its molecular characteristics and resistance mechanisms.
Weili Zhang, Hao Xu, Yaling Li, Ruishan Liu, Danfeng Lou   +4 more
doaj   +1 more source

The Frequency of Escherichia coli Strain Isolates Causing Urinary Tract Infections in the presence of Pathogenic Aerobactin Genes

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2015
BACKGROUND AND OBJECTIVE: Escherichia-coli is one of the major causes of urinary tract infection (UTI). The strains of this bacterium have a variety of virulence factors, such as iron acquisition systems, that provide the energy for iron transport ...
SM Mojabi, R Ranjbar
doaj  

Bio inspired microfluidic-based analysis of Klebsiella pneumoniae virulence factors and antimicrobial resistance

SLAS Technology
The objective of this research was to examine the antibiotic resistance and microbiological traits of Klebsiella pneumoniae isolates that were responsible for liver abscesses in Qingdao, China.
Xiaoping Song, Jun zhang, Weihong Hua, Yan Zheng, Xiaolin Liu, Yuanqi Zhu, Sun Bin, Jian Ding, Suling Sun   +8 more
doaj   +1 more source

Tracking key virulence loci encoding aerobactin and salmochelin siderophore synthesis in Klebsiella pneumoniae

Genome Medicine, 2018
Background Klebsiella pneumoniae is a recognised agent of multidrug-resistant (MDR) healthcare-associated infections; however, individual strains vary in their virulence potential due to the presence of mobile accessory genes.
Margaret M. C. Lam, Kelly L. Wyres, Louise M. Judd, Ryan R. Wick, Adam Jenney, Sylvain Brisse, Kathryn E. Holt   +6 more
doaj   +1 more source

NDM-1-Positive K. pneumoniae at a Teaching Hospital in Southwestern China: Clinical Characteristics, Antimicrobial Resistance, Molecular Characterization, Biofilm Assay, and Virulence

Canadian Journal of Infectious Diseases and Medical Microbiology, 2020
Background. The emergence of the NDM-1-positive Klebsiella pneumoniae (K. pneumoniae) strains has led to limited therapeutic options for clinical treatment.
Kai Yang, Shumin Liu, Huanqin Li, Na Du, Jing Yao, Qiuyue He, Yan Du   +6 more
doaj   +1 more source

Hypervirulent Klebsiella pneumoniae (hypermucoviscous and aerobactin positive) infection over 6 years in the elderly in China: antimicrobial resistance patterns, molecular epidemiology and risk factor

Annals of Clinical Microbiology and Antimicrobials, 2019
Background The definition of hypervirulent Klebsiella pneumoniae (hvKp), traditionally regarded as hypermucoviscosity, is controversial. However, data based on both phenotype (hypermucoviscous) and genetic (aerobactin) criteria are limited.
Chao Liu, Jun Guo
doaj   +1 more source

Analysis of the Type VI secretion system and microbiological characteristics of hypervirulent Klebsiella pneumoniae causing urinary tract infections

Journal of Infection in Developing Countries
Introduction: This study aimed to evaluate the Type VI secretion system (T6SS) and microbiological features in hypervirulent Klebsiella pneumoniae (hvKP) causing urinary tract infections (UTIs) in hospitalized adults.
Fei-Fei Li, Jing-Jing Li, Yin Zhang, Zhi-Yu Wu, Yuan-Hong Xu   +4 more
doaj   +3 more sources

Deciphering the relative importance of genetic elements in hypervirulent Klebsiella pneumoniae to guide countermeasure developmentResearch in context

EBioMedicine
Summary: Background: Quantitating the contribution of phenotype-responsible elements in hypervirulent Klebsiella pneumoniae is needed. Methods: Isogenic mutants of four hypervirulent clinical isolates that produced K1 (ST23), K2 (ST86), K20 (ST1544), or
Thomas A. Russo, Ulrike Carlino-MacDonald, Zachary J. Drayer, Connor J. Davies, Cassandra L. Alvarado, Alan Hutson, Ting L. Luo, Melissa J. Martin, Patrick T. McGann, Francois Lebreton   +9 more
doaj   +1 more source

Complete genome and comparative genomic analysis of cefpodoxime resistant Pantoea septica strain GABEPS69 isolated from saliva of a patient diagnosed with treatment resistant schizophrenia

International Journal of Medical Microbiology
Objectives: This study aims to generate the first complete genome of Pantoea septica and provide a thorough genomic characterisation of this under-documented species. The study seeks to enhance understanding of P. septica, clarifying features relevant to
Francesca McDonagh, Aneta Kovarova, Anna Tumeo, Andy O’Connor, Niamh McEvoy, Aneesa Mangalam Lonappan, Kasthuri Venkateswaran, Elaine K. Murray, Brian Hallahan, Georgios Miliotis   +9 more
doaj   +1 more source

Emergence of blaKPC-71 variant and loss of aerobactin-encoding genes (iucABCD-iutA) in ST11-K64 carbapenem-resistant Klebsiella pneumoniae during ceftazidime–avibactam treatment

Journal of Global Antimicrobial Resistance
Objective: To investigate the within-host evolutionary dynamics of resistance and virulence in carbapenem-resistant Klebsiella pneumoniae during ceftazidime-avibactam treatment. Methods: Three K.
Fang-ling Du, Dan-dan Wei, Yong-qing Guo, Peng Liu, Yan-fang Mei, Shan-shan Huang, Qi-sen Huang, Lin-Ping Fan, Yang Liu   +8 more
doaj   +1 more source