Results 1 to 10 of about 107,974 (142)

A single chlamydial protein reshapes the plasma membrane and serves as recruiting platform for central endocytic effector proteins

open access: yesCommunications Biology, 2023
Uptake of obligate intracellular bacterial pathogens into mammalian epithelial cells is critically dependent on modulation of the host’s endocytic machinery.
Dominik Spona   +3 more
doaj   +1 more source

Visualization for genomics: the Microbial Genome Viewer [PDF]

open access: yesBioinformatics, 2004
Abstract Summary: A Web-based visualization tool, the Microbial Genome Viewer, is presented that allows the user to combine complex genomic data in a highly interactive way. This Web tool enables the interactive generation of chromosome wheels and linear genome maps from genome annotation data stored in a MySQL database.
Robert Kerkhoven   +4 more
openaire   +5 more sources

Pangenome analysis reveals genetic isolation in Campylobacter hyointestinalis subspecies adapted to different mammalian hosts

open access: yesScientific Reports, 2021
Campylobacter hyointestinalis is an emerging pathogen currently divided in two subspecies: C. hyointestinalis subsp. lawsonii which is predominantly recovered from pigs, and C. hyointestinalis subsp.
Daniela Costa   +6 more
doaj   +1 more source

The 4-α-Glucanotransferase AcbQ Is Involved in Acarbose Modification in Actinoplanes sp. SE50/110

open access: yesMicroorganisms, 2023
The pseudo-tetrasaccharide acarbose, produced by Actinoplanes sp. SE50/110, is a α-glucosidase inhibitor used for treatment of type 2 diabetes patients.
Sophia Nölting   +5 more
doaj   +1 more source

Human microbiota drives hospital-associated antimicrobial resistance dissemination in the urban environment and mirrors patient case rates

open access: yesMicrobiome, 2022
Background The microbial community composition of urban environments is primarily determined by human activity. The use of metagenomics to explore how microbial communities are shaped in a city provides a novel input that can improve decisions on public ...
Cecilia Salazar   +12 more
doaj   +1 more source

Genomic characterization of the C. tuberculostearicum species complex, a prominent member of the human skin microbiome

open access: yesmSystems, 2023
Corynebacterium is a predominant genus in the skin microbiome, yet its genetic diversity on the skin is incompletely characterized and underrepresented in public databases.
Nashwa Ahmed   +6 more
doaj   +1 more source

Microbial genomic taxonomy [PDF]

open access: yesBMC Genomics, 2013
A need for a genomic species definition is emerging from several independent studies worldwide. In this commentary paper, we discuss recent studies on the genomic taxonomy of diverse microbial groups and a unified species definition based on genomics. Accordingly, strains from the same microbial species share >95% Average Amino Acid Identity (AAI) and ...
Thompson, Cristiane C   +5 more
openaire   +3 more sources

Author Correction: The chromosomal organization of horizontal gene transfer in bacteria

open access: yesNature Communications, 2020
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Pedro H. Oliveira   +3 more
doaj   +1 more source

Adaptation to novel spatially-structured environments is driven by the capsule and alters virulence-associated traits

open access: yesNature Communications, 2022
Phenotypic and genotypic evolution in worrisome Klebsiella spp. is influenced by the capsule. Here the authors show that adaptation outside the host can impact virulence-associated traits, including de novo emergence of hypermucoviscosity.
Amandine Nucci   +2 more
doaj   +1 more source

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