Results 61 to 70 of about 93,738 (272)

High MBL-expressing genotypes are associated with deterioration in renal function in type 2 diabetes

Frontiers in Immunology, 2022
IntroductionAccumulating evidence support that mannan-binding lectin (MBL) is a promising prognostic biomarker for risk-stratification of diabetic micro- and macrovascular complications.
G. H. Dørflinger, G. H. Dørflinger, P. H. Høyem, E. Laugesen, J. A. Østergaard, J. A. Østergaard, K. L. Funck, K. L. Funck, R. Steffensen, P. L. Poulsen, P. L. Poulsen, T. K. Hansen, M. Bjerre   +12 more
doaj   +1 more source

#MarielleVive y el MBL

Virtualis, 2022
Este artículo analiza algunos de los espacios digitales del Movimento Brasil Livre (MBL), uno de los representantes de la llamada “nueva derecha” brasileña, centrándose en las acciones del grupo en la proliferación de noticias falsas con motivo del asesinato de la política brasileña Marielle Franco en marzo de 2018.
openaire   +1 more source

Cars2‐Mediated Cysteine Catabolism Drives Brown Fat Development and Thermogenesis Through Persulfidating EBF2

Advanced Science, EarlyView.
We demonstrate that Cars2, a cysteine catabolic enzyme in mouse iBAT, is critical for cold tolerance and brown adipocyte differentiation. Through its CPERS activity, Cars2 produces CysSSH/H2S to induce EBF2 persulfidation, promoting its interaction with PPARγ and BRG1 to enhance thermogenic gene expression.
Xin Peng, Hongyong Song, Yin Long, Kaimin Wu, Yinkun Fu, Wenkai Zhou, Wenyan Li, Zhe Shi, Xu‐Yun Zhao   +8 more
wiley   +1 more source

Antimicrobial peptide LL-37 and recombinant human mannose-binding lectin express distinct age- and pathogen-specific antimicrobial activity in human newborn cord blood in vitro [PDF]

, 2018
Background: There is a need to prevent and treat infection in newborns. One approach is administration of antimicrobial proteins and peptides (APPs) such as LL-37, a membrane-active cathelicidin antimicrobial peptide, and mannose-binding lectin (MBL), a ...
Borriello, Francesco, Jeffers, Carleen, Joshi, Sweta, Levy, Ofer, Li, Ning, Ozonoff, Al, Pettengill, Matthew, Scheid, Annette   +7 more
core   +1 more source

Distinct Pathways of Mannan-Binding Lectin (MBL)- and C1-Complex Autoactivation Revealed by Reconstitution of MBL with Recombinant MBL-Associated Serine Protease-2 [PDF]

The Journal of Immunology, 2000
Abstract Mannan-binding lectin (MBL) plays a pivotal role in innate immunity by activating complement after binding carbohydrate moieties on pathogenic bacteria and viruses. Structural similarities shared by MBL and C1 complexes and by the MBL- and C1q-associated serine proteases, MBL-associated serine protease (MASP)-1 and MASP-2, and ...
Vorup-Jensen, T, Petersen, Steen Vang, Hansen, A G, Poulsen, Knud, Schwaeble, W, Sim, R B, Reid, K B, Davis, S J, Thiel, S, Jensenius, J C   +9 more
openaire   +3 more sources

Multi‐scale Optimization on Interfacial Evaporative Cooling for Photovoltaic Performance Enhancement

Advanced Science, EarlyView.
This study presents a passive siphon‐driven interfacial evaporative cooling technology for photovoltaics. A multiscale multiphysics model is developed and validated experimentally. Results show that optimizing installation parameters reduces operating temperature by up to 22.3 °C and boosts power efficiency by 8.9%, offering a practical pathway for ...
Fuxiang Li, Haosheng Lin, Zengguang Sui, Yunren Sui, Zhixiong Ding, Wei Wu   +5 more
wiley   +1 more source

Prevalence of Extended-spectrum Beta-lactamase (ESBL), Metallo Beta-lactamase (MBL) and Carbapenemase Producing Acinetobacter Species Isolated from Various Clinical Samples in Tertiary Care Hospital

Journal of Pure and Applied Microbiology
Acinetobacter is an important nosocomial pathogen causing health care associated infections. It is highly antibiotic resistant gram-negative bacilli. The study was done to determine the prevalence of Acinetobacter species isolated from various clinical ...
Manasi Vikas Yadav, Geeta S. Karande, S.N. Karande, S.R. Patil, Shanu Sharma   +4 more
doaj   +1 more source

Constructing local integrals of motion in the many-body localized phase

, 2014
Many-body localization provides a generic mechanism of ergodicity breaking in quantum systems. In contrast to conventional ergodic systems, many-body localized (MBL) systems are characterized by extensively many local integrals of motion (LIOM), which ...
Abanin, Dmitry A., Chandran, Anushya, Kim, Isaac H., Vidal, Guifre   +3 more
core   +1 more source

Inhibition of Focal Adhesion Restricts Chemoresistance in Pancreatic Cancer by Targeting SLC7A11 Mediated Ferroptosis

Advanced Science, EarlyView.
FAK signaling drives chemoresistance and tumor evolution in pancreatic ductal adenocarcinoma. The FAK inhibitor IN10018 restores gemcitabine sensitivity by inducing SLC7A11‐mediated ferroptosis through the PI3K‐Akt pathway and remodeling the tumor microenvironment, reducing mesenchymal components while enhancing CD8+ T‐cell infiltration in preclinical ...
Yingjin Wang, Hui Yang, Baoyuan Zhang, Yongsu Ma, Kuangen Zhang, Peng Wang, Jiapeng Yang, Zaiqi Wang, Rong Liu, Xiaodong Tian, Ning Zhang, Yinmo Yang   +11 more
wiley   +1 more source

Detección Fenotípica de Carbapenemasas en Pseudomonas aeruginosa en Pacientes que acudieron al Hospital de Clínicas San Lorenzo de febrero a julio 2013

Memorias del Instituto de Investigaciones en Ciencias de la Salud, 2016
Pseudomonas aeruginosa es uno de los patógenos oportunistas más importantes, causante de infecciones, con alto índice de morbi-mortalidad. Los carbapenemes son antibióticos que poseen un amplio espectro de actividad y son altamente potentes, que los ...
Clotilde Ophelie Marie Molin Queste
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